Clinical Trials Browser

Brain Neoplasms, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT07390539 2026-02-05

B7-H3.CD28Z.CART in CNS Neoplasms

Brain Neoplasms, Ependymoma, Medulloblastoma, Meningeal Neoplasms, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT03025256 2026-01-08

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

Phase 1 Active not recruiting

71 enrolled

DermatologicThoracic

Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Meningeal Neoplasms, Nevus

NCT05809752 2026-01-08

A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)

Phase 1 Recruiting

18 enrolled

Breast

Meningeal Neoplasms, Triple Negative Breast Neoplasms

NCT05112549 2025-04-03

IT-PD1

Phase 1 Recruiting

46 enrolled

Meningeal Neoplasms

NCT03711422 2022-06-14

Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC

Phase 1 Terminated

2 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Meningeal Neoplasms

NCT00062881 2020-03-04

Intrathecal Mafosfamide

Phase 1 Completed

65 enrolled

LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Meningeal Neoplasms, Neoplasms

NCT00512460 2016-05-16

RTA 744 Injection in Patients With Leptomeningeal Disease

Phase 1 Terminated

7 enrolled

CNSLymphoidOther hematologic neoplasm

Brain Neoplasms, Leukemia, Lymphoma, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT00515788 2012-03-12

DepoCyt Plus Temozolomide in Patients With Neoplastic Meningitis

Phase 1 Terminated

11 enrolled

CNS

Meningeal Neoplasms, Meningeal Carcinomatosis

Clinical Trials

Avelumab With Radiotherapy in Patients With Leptomeningeal Disease

B7-H3.CD28Z.CART in CNS Neoplasms

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)

IT-PD1

Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC

Intrathecal Mafosfamide

RTA 744 Injection in Patients With Leptomeningeal Disease

DepoCyt Plus Temozolomide in Patients With Neoplastic Meningitis