Clinical Trials

80 trials
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NCT04806620 2026-01-22

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Brain Inflammation Collaborative

Recruiting
10,000 enrolled

Pediatric acute-onset neuropsychiatric syndrome, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections, Brain Injuries, Traumatic, Phobia, Social, Post-Lyme Disease Syndrome, Avoidant Restrictive Food Intake Disorder, Mast Cell Activation Syndrome, Neuroinflammatory Diseases, Psychological Well-Being, Post-Acute COVID-19 Syndrome, Generalized Anxiety Disorder, Anorexia Nervosa, Anxiety Disorders, Arthritis, Juvenile, Autoimmune Diseases, Autonomic Nervous System Diseases, Mental Disorders, Celiac Disease, Colitis, Ulcerative, Combat Disorders, Crohn Disease, Depression, Ehlers-Danlos Syndrome, Encephalitis, Endometriosis, Fatigue, Mental Fatigue, Fibromyalgia, Tourette Syndrome, Migraine Disorders, Multiple Sclerosis, Myasthenia Gravis, Narcolepsy, Obsessive-Compulsive Disorder, Psoriasis, Rheumatic Fever, Spondylitis, Ankylosing, Stress Disorders, Post-Traumatic, Inflammatory Bowel Diseases, Arthritis, Psoriatic, Fatigue Syndrome, Chronic, Mood Disorders, Autoimmune Diseases of the Nervous System, Bulimia Nervosa, Postural Orthostatic Tachycardia Syndrome

NCT04031469 2025-07-31

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

ProgenaBiome

Suspended
1,000 enrolled
GastrointestinalOtherOther solid neoplasmThoracic

Autism Spectrum Disorder, Bipolar and Related Disorders, Post-Lyme Disease Syndrome, Generalized Anxiety Disorder, Acne Vulgaris, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Anxiety Disorders, Arthritis, Rheumatoid, Autistic Disorder, Bipolar Disorder, Celiac Disease, Colitis, Ulcerative, Colonic Neoplasms, Compulsive Personality Disorder, Constipation, Crohn Disease, Depression, Depressive Disorder, Major, Diabetes Mellitus, Eczema, Epidermolysis Bullosa, Gout, Hypercholesterolemia, Lyme Disease, Mesothelioma, Migraine Disorders, Multiple Sclerosis, Myasthenia Gravis, Neoplasms, Obsessive-Compulsive Disorder, Parkinson Disease, Psoriasis, Colorectal Neoplasms, Fatigue Syndrome, Chronic, Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Relapsing-Remitting, Lyme Neuroborreliosis, Irritable Bowel Syndrome

NCT01793168 2025-05-29

CoRDS

Sanford Health

Recruiting
20,000 enrolled
Classical hematologyDermatologicEndocrineGastrointestinalHead & NeckMyeloidSarcoma

Leukoencephalopathy Brain Calcifications and Cysts, Aniridia, Partial, with Unilateral Renal Agenesis and Psychomotor Retardation, Recurrent respiratory papillomatosis, Cerebellar ataxia ectodermal dysplasia, CAPOS syndrome, Chromosome 1p36 Deletion Syndrome, Ataxia with vitamin E deficiency, Chronic recurrent multifocal osteomyelitis, Episodic Ataxia, Type 2, Harding ataxia, Axenfeld-Rieger syndrome, Emanuel syndrome, Erythrokeratodermia with ataxia, Eosinophilic enteropathy, Achalasia Addisonianism Alacrimia syndrome, Maternally Inherited Leigh Syndrome, Nicolaides Baraitser syndrome, Trimethylaminuria, Warburg Sjo Fledelius syndrome, Spastic ataxia Charlevoix-Saguenay type, Turcot syndrome, KBG syndrome, Spinocerebellar ataxia 13, Spinocerebellar ataxia 14, Sensorimotor neuropathy with ataxia, autosomal dominant, Spinocerebellar ataxia 20, Spinocerebellar ataxia 21, Spinocerebellar ataxia 23, Spinocerebellar ataxia 25, Spinocerebellar ataxia 26, Spinocerebellar ataxia 27, Spinocerebellar ataxia 28, Sacral defect and anterior sacral meningocele, Spinocerebellar ataxia 8, Spinocerebellar ataxia, autosomal recessive 1, Spinocerebellar ataxia, autosomal recessive 3, Spinocerebellar ataxia, X-linked, 3, Spinocerebellar ataxia, X-linked, 4, Neuropathy ataxia and retinitis pigmentosa, Pitt-Hopkins syndrome, Bohring syndrome, Stickler syndrome, type 1, Stickler syndrome, type 2, Jansen type metaphyseal chondrodysplasia, Growth mental deficiency syndrome of Myhre, Kabuki syndrome, Laryngeal papillomatosis, Peters anomaly, Early-onset ataxia with oculomotor apraxia and hypoalbuminemia, Sucrase-isomaltase deficiency, congenital, Blau syndrome, Acrodysostosis, Cataract ataxia deafness, Potocki-Shaffer syndrome, Hypophosphatasia, Childhood, Hypophosphatasia, Adult, Cystinosis, Late-Onset Juvenile or Adolescent Nephropathic Type, Muscular Atrophy, Ataxia, Retinitis Pigmentosa, and Diabetes Mellitus, Episodic Ataxia, Type 1, Cerebellar Ataxia, Cayman Type, Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dementia, Olivopontocerebellar Atrophy V, Myoclonus, Cerebellar Ataxia, and Deafness, Spinocerebellar Ataxia, Autosomal Recessive 7, Fragile X Tremor Ataxia Syndrome, Odontohypophosphatasia, Spinocerebellar Ataxia with Epilepsy, Spinocerebellar Ataxia 15, Episodic Ataxia, Type 3, Episodic Ataxia, Type 4, Spastic Ataxia, Spinocerebellar Ataxia, Autosomal Recessive 8, Dimethylglycine Dehydrogenase Deficiency, Growth Deficiency and Mental Retardation with Facial Dysmorphism, Cystinosis, Infantile Nephropathic, 3-Methylglutaconic Aciduria, Type V, Spinocerebellar Ataxia 11, Ataxia Telangiectasia Like Disorder, Spinocerebellar Ataxia 12, Cerebellar Ataxia and Hypogonadotropic Hypogonadism, Spinocerebellar Ataxia 31, Brachydactyly-Nystagmus-Cerebellar Ataxia, Ataxia, Spastic, with Congenital Miosis, Aniridia and Absent Patella, Hereditary Myopathy with Early Respiratory Failure, Episodic Ataxia, Type 5, Sacral Agenesis Syndrome, Paroxysmal Tonic Upgaze, Benign Childhood, With Ataxia, Ataxia-Telangiectasia Variant, Spinocerebellar Ataxia 10, Ataxia, Spastic, 3, Autosomal Recessive, Multiple Endocrine Neoplasia, Type IV, Hypophosphatasia, Perinatal Lethal, Polyneuropathy, Hearing Loss, Ataxia, Retinitis Pigmentosa, And Cataract, Episodic Ataxia, Type 6, Episodic Ataxia, Type 7, Spinocerebellar ataxia 30, Ataxia Neuropathy Spectrum, Hereditary Sensory and Autonomic Neuropathy Type Ie, Cauda Equina Syndrome, Olivary Degeneration, Addison Disease, Ataxia, Ataxia Telangiectasia, Beckwith-Wiedemann Syndrome, Biliary Atresia, Cockayne Syndrome, Cystinosis, De Lange Syndrome, Deafness, Esophageal Achalasia, Friedreich Ataxia, Glycogen Storage Disease, Halitosis, Hirschsprung Disease, Disorders of Excessive Somnolence, Hypophosphatasia, Infections, Intestinal Pseudo-Obstruction, Klippel-Feil Syndrome, Leigh Disease, Leiomyosarcoma, Leukodystrophy, Metachromatic, Liver Cirrhosis, Biliary, Lyme Disease, Meningitis, Viral, Moyamoya Disease, Mucocutaneous Lymph Node Syndrome, Mucolipidoses, Muscle Spasticity, Myasthenia Gravis, Myoclonus, Narcolepsy, Multiple Endocrine Neoplasia, Neuronal Ceroid-Lipofuscinoses, Hereditary Sensory and Autonomic Neuropathies, Oculocerebrorenal Syndrome, Hyperacusis, Rectal Fistula, Refsum Disease, Retinitis Pigmentosa, Scheuermann Disease, Short Bowel Syndrome, Spinocerebellar Degenerations, Syndrome, Pyruvate Dehydrogenase Complex Deficiency Disease, Lambert-Eaton Myasthenic Syndrome, Aniridia, Alagille Syndrome, Kleine-Levin Syndrome, WAGR Syndrome, Machado-Joseph Disease, Multiple Endocrine Neoplasia Type 1, Multiple Endocrine Neoplasia Type 2a, Multiple Endocrine Neoplasia Type 2b, Williams Syndrome, Multiple System Atrophy, Hyperglycinemia, Nonketotic, Hyperargininemia, Idiopathic Hypersomnia, Amnesia, Transient Global, Spinocerebellar Ataxias, Myasthenia Gravis, Neonatal, Mitochondrial Diseases, Optic Atrophy, Autosomal Dominant, Denys-Drash Syndrome, Rare Diseases, Coffin-Lowry Syndrome, Muscular Dystrophy, Oculopharyngeal, beta-Mannosidosis, Scleroderma, Diffuse, Lymphohistiocytosis, Hemophagocytic, Frasier Syndrome, Wolf-Hirschhorn Syndrome, Bulbo-Spinal Atrophy, X-Linked, Alstrom Syndrome, Leber Congenital Amaurosis, Frontotemporal Dementia, Neglected Diseases, Atypical Hemolytic Uremic Syndrome

NCT06539169 2024-11-14

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

xCures

Recruiting
1,000 enrolled
Classical hematologyOtherPlasma cell

Alzheimer Disease, Amyloidosis, Amyotrophic Lateral Sclerosis, Anemia, Sickle Cell, Cystic Fibrosis, Ehlers-Danlos Syndrome, Gaucher Disease, Glycogen Storage Disease Type II, Huntington Disease, Myasthenia Gravis, Gangliosidosis, GM1, alpha-Thalassemia, beta-Thalassemia, Muscular Dystrophy, Duchenne, Insomnia, Fatal Familial, Rare Diseases

NCT05635266 2024-05-07

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Sanguine Biosciences

Recruiting
20,000 enrolled
Classical hematologyGenitourinaryHead & NeckLymphoidOther hematologic neoplasmPlasma cell

red meat allergy, Alopecia Areata, Alzheimer Disease, Amyloidosis, Anemia, Sickle Cell, Arthritis, Asthma, Autistic Disorder, Behcet Syndrome, Celiac Disease, Colitis, Ulcerative, Crohn Disease, Cystic Fibrosis, Dermatitis, Atopic, Diabetes Mellitus, Epilepsies, Myoclonic, Fibrosis, Fibromyalgia, Graves Disease, Heart Diseases, Hepatitis, Hypersensitivity, Kidney Diseases, Leukemia, Lupus Erythematosus, Systemic, Lymphoma, Macular Degeneration, Multiple Sclerosis, Myasthenia Gravis, Neoplasms, Parkinson Disease, Pemphigus, Psoriasis, Schizophrenia, Spondylitis, Ankylosing, Thyroid Diseases, Vasculitis, Vitiligo, beta-Thalassemia, Hidradenitis Suppurativa, Hepatitis, Autoimmune, Stroke, Pulmonary Disease, Chronic Obstructive, Scleroderma, Diffuse