NCT03813147 2025-04-13Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic SyndromeNational Cancer Institute (NCI)Phase 1 Completed12 enrolled 16 charts
NCT03814005 2024-09-05A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver ProblemsTakedaPhase 1 Completed17 enrolled 33 charts
NCT02782468 2023-11-03A Study of Pevonedistat in Adult East Asian ParticipantsTakedaPhase 1 Completed23 enrolled 23 charts
NCT04712942 2023-08-21Treatment of MDS/AML Patients With an Impending Hematological Relapse With AZA or ATA and PevonedistatUniversity of LeipzigPhase 2 Completed14 enrolled
NCT02610777 2022-09-19An Efficacy and Safety Study of Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine in Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML) and Low-Blast Acute Myelogenous Leukemia (AML)TakedaPhase 2 Completed120 enrolled 39 charts
NCT00911066 2013-12-05MLN4924 for the Treatment of Acute Myelogenous Leukemia, Myelodysplastic Syndrome, and Acute Lymphoblastic LeukemiaMillennium Pharmaceuticals, Inc.Phase 1 Completed72 enrolled