Clinical Trials Browser

Neoplasm Metastasis × Radiotherapy × Clear all

NCT05124912 2026-02-20

REMASTer: REcurrent Brain Metastases After SRS Trial

Phase NA Recruiting

Brain Neoplasms, Neoplasm Metastasis, Recurrence

NCT05039632 2026-02-06

Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies

Phase 1/2 Recruiting

Neoplasm Metastasis

NCT02560636 2026-01-06

PLUMMB

Phase 1 Active not recruiting

Neoplasm Metastasis

NCT00929214 2025-12-17

Aggressive Local Therapy for Limited Bone-Only Metastasis to Improve Progression-Free Survival in Breast Cancer Patients

Phase 2 Active not recruiting

Breast Neoplasms, Neoplasm Metastasis

NCT07274774 2025-12-10

SBRT Plus Systemic Therapy vs Systemic Therapy Alone in BCLC C Hepatocellular Carcinoma

Phase 2 Recruiting

Gastrointestinal

Carcinoma, Hepatocellular, Neoplasm Metastasis

NCT02639026 2025-11-25

Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic Cancers

Phase 1 Completed

BreastDermatologicGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT03217747 2025-10-23

Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies

Phase 1/2 Active not recruiting

173 enrolled 28 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT07111104 2025-08-08

ARIS

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT07043608 2025-07-02

ZAMBONI

Phase 2 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Neoplasm Metastasis

NCT05555342 2025-05-14

A Novel Method for Treating Lung Met w/Combo of Electric Fields & Rad Therapy: A Single-Arm

Phase EARLY_PHASE1 Completed

Lung Neoplasms, Neoplasm Metastasis

NCT06306924 2025-05-01

UNC Metastatic Cancer Radiation Therapy Registry

Neoplasm Metastasis, Neoplasms

NCT03705403 2025-01-30

IMMUNOSABR2

Phase 2 Terminated

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT03824366 2025-01-10

MAP-RT

Phase NA Completed

20 enrolled 8 charts

Gastrointestinal

Hemoptysis, Gastrointestinal Hemorrhage, Mediastinal Diseases, Neoplasm Metastasis, Neoplasms, Superior Vena Cava Syndrome

NCT05352178 2024-07-03

SPARKLE

Phase 3 Recruiting

Neoplasm Metastasis, Prostatic Neoplasms

NCT00080912 2023-08-21

Single vs Multiple-Fraction Therapy in Treating Patients With Previously Irradiated Painful Bone Metastases

Phase NA Completed

850 enrolled 8 charts

Neoplasm Metastasis, Pain

NCT00080938 2023-06-29

Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer

Phase 2 Completed

26 enrolled 8 charts

Adenocarcinoma of Lung, Brain Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT01751438 2023-04-27

Best Systemic Therapy or Best Systemic Therapy (BST) Plus Definitive Treatment (Radiation or Surgery)

Phase 2 Completed

Neoplasm Metastasis, Prostatic Neoplasms

NCT05755009 2023-03-07

ST-CR01

Phase NA Unknown

Neoplasm Metastasis

NCT03453892 2023-02-16

ST-ICI

Neoplasm Metastasis

NCT00377156 2022-09-16

Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Phase 3 Completed

213 enrolled 16 charts

BreastCNSGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms, Breast Neoplasms, Male

NCT01759238 2022-07-01

OLGA

Phase 2 Terminated

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT05334459 2022-04-26

Preoperative Radiotherapy and Systemic Therapy Following Surgery in 'de Novo' Metastatic Breast Cancer

Breast Neoplasms, Neoplasm Metastasis

NCT02499367 2022-03-22

TONIC

Phase 2 Unknown

Breast Neoplasms, Neoplasm Metastasis

NCT00005887 2021-08-23

Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases

Phase 3 Completed

Brain Neoplasms, Neoplasm Metastasis

NCT01461252 2021-07-16

Safety and Efficacy of Cryoablation Combined With Radiation Therapy for the Palliation of Painful Bone Metastases

Phase 1 Withdrawn

Bone Neoplasms, Neoplasm Metastasis, Pain

NCT04873440 2021-05-05

An Open-label, Phase I/II Study of Manganese Plus Radiotherapy in Patients With Metastatic Solid Tumors or Lymphoma

Phase 1/2 Unknown

Lymphoma, Neoplasm Metastasis

NCT00031967 2020-10-22

Melatonin and Radiation Therapy in Treating Patients With Brain Metastases

Phase 2 Completed

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries

NCT02221739 2020-05-11

Study of Combined Ionizing Radiation and Ipilimumab in Metastatic Non-small Cell Lung Cancer (NSCLC)

Phase 1/2 Completed

39 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Neoplasms

NCT03022734 2020-01-13

Short Course Radiotherapy, Unresectable Rectal Cancer, Liver Metastasis

Phase 2 Unknown

Gastrointestinal

Neoplasm Metastasis, Rectal Neoplasms

NCT03543696 2019-07-23

OLIGO

Phase NA Unknown

Neoplasm Metastasis

NCT00540969 2018-11-21

Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases

Phase 3 Terminated

3 enrolled 1 chart

DermatologicGenitourinary

Carcinoma, Renal Cell, Kidney Neoplasms, Melanoma, Neoplasm Metastasis, Pain

NCT00769990 2017-12-13

Genistein in Treating Patients Undergoing External-Beam Radiation Therapy for Bone Metastases

Phase 1/2 Withdrawn

BreastDermatologicGenitourinaryThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pain, Prostatic Neoplasms, Small Cell Lung Carcinoma

NCT00946673 2017-10-06

Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

Phase 1 Completed

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT02474186 2017-08-03

Phase II Study for Solid Metastatic Tumors

Phase 2 Completed

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00280748 2017-06-23

NRR

Phase 2 Terminated

10 enrolled 14 charts

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00983359 2017-06-06

Stereotactic Radiation Therapy in Treating Patients With Brain Metastases

Phase NA Completed

40 enrolled 11 charts

Brain Neoplasms, Neoplasm Metastasis

NCT00328575 2016-10-21

Using Intensity Modulated Radiation Therapy (IMRT) for Brain Metastases

Phase 1 Completed

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00030628 2016-07-07

Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Phase 3 Completed

Brain Neoplasms, Neoplasm Metastasis

NCT00003162 2015-11-17

Radiation Therapy in Treating Patients With Bone Metastases From Breast or Prostate Cancer

Phase 3 Completed

BreastGenitourinary

Breast Neoplasms, Neoplasm Metastasis, Pain, Prostatic Neoplasms

NCT00255814 2015-11-17

Radiation Therapy in Treating Patients With Liver Metastases

Phase 1 Completed

Neoplasm Metastasis

NCT01427322 2015-07-08

Randomized RT +/- Lapatinib for Advanced Solid Tumor Cancer Patients Receiving Radiation Therapy for Metastatic Disease

Phase EARLY_PHASE1 Terminated

Neoplasm Metastasis

NCT00002708 2013-11-19

Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases

Phase 3 Completed

Brain Neoplasms, Neoplasm Metastasis

NCT00403065 2013-08-26

Dexamethasone and Supportive Care With or Without Whole-Brain Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer That Has Spread to the Brain and Cannot Be Removed By Surgery

Phase 3 Completed

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00020839 2012-09-24

Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That Is Metastatic to the Brain

Phase 3 Terminated

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT00002899 2012-07-02

Adjuvant Radiation Therapy in Treating Patients With Brain Metastases

Phase 3 Terminated

Brain Neoplasms, Neoplasm Metastasis

NCT00238251 2012-06-05

Radiation Therapy Combined With Either Gefitinib or Temozolomide in Pats With NSCLC and Brain Metastases

Phase 2 Completed

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00918593 2011-09-27

Palliative Treatment of Ulcerated Cutaneous Metastases: Trial Between Electrochemotherapy and Radiotherapy

Phase 2 Withdrawn

Neoplasm Metastasis, Ulcer

NCT00875355 2009-08-26

Radiation Therapy With or Without Temozolomide in Treating Women With Brain Metastases and Breast Cancer

Phase 2 Unknown

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis