Clinical Trials Browser

Interventional × Neoplasm Metastasis × bintrafusp alfa protein, human × Clear all

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Hematologic Neoplasms, Triple Negative Breast Neoplasms

NCT04874311 2025-08-13

TRUST

Phase 2 Recruiting

80 enrolled

Sarcoma

Tertiary Lymphoid Structures, Neoplasm Metastasis, Sarcoma

NCT04574583 2025-02-03

Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)

Phase 1/2 Completed

12 enrolled 17 charts

Tumor-Agnostic

Neoplasm Metastasis

NCT03436563 2024-11-27

M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability

Phase 1/2 Completed

4 enrolled 7 charts

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms, Microsatellite Instability

NCT04396886 2024-05-09

Bintrafusp Alfa in Previously Treated Patients With R/M Non-keratinizing NPC

Phase 2 Completed

38 enrolled

Head & Neck

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

Clinical Trials

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

TRUST

Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)

M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability

Bintrafusp Alfa in Previously Treated Patients With R/M Non-keratinizing NPC