Clinical Trials

93 enrolled

Neoplasm Metastasis, Recurrence

NCT05415475 2024-01-05

Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced Malignant Solid Tumors

Esophageal Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Recurrence, Stomach Neoplasms, Colorectal Neoplasms

NCT04987112 2023-12-22

Intratumoral CAN1012(Selective TLR7 Agonist) in Subjects With Solid Tumors

Neoplasm Metastasis

NCT06087770 2023-12-18

Clinical Study of SM3321 With Solid Tumors

48 enrolled

Neoplasm Metastasis

NCT06117371 2023-11-07

Study of BEBT-607 Tablets in The Treatment of Advanced or Metastatic Solid Tumors With KRAS G12C Mutation

126 enrolled

Neoplasm Metastasis

NCT05094804 2023-11-02

A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents

DermatologicHead & NeckSarcomaThoracic

172 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Leiomyosarcoma, Liposarcoma, Melanoma, Neoplasm Metastasis, Neoplasms

NCT03129139 2023-10-18

Minnelide 101

66 enrolled

BreastGastrointestinal

Breast Neoplasms, Colonic Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Stomach Neoplasms

NCT05420519 2023-08-18

Clinical Study of CD70-targeted CAR-T Therapy for Advanced/Advanced Renal Cancer

24 enrolled

Genitourinary

Carcinoma, Renal Cell, Neoplasm Metastasis

NCT05420545 2023-08-18

A Clinical Study of CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors

GenitourinaryGynecologic

Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms

NCT05468190 2023-08-18

A Clinical Research About CD70-positive Advanced/Metastatic Solid Tumors Treated by CD70-targeted CAR-T

48 enrolled

GenitourinaryGynecologic

Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms

NCT04033354 2023-08-08

A Randomized, Double-blind, Placebo Controlled Phase III Study to Investigate Efficacy and Safety of First-Line Treatment With HLX10 + Chemotherapy (Carboplatin-Nanoparticle Albumin Bound (Nab) Paclitaxel) in Patients With Stage IIIB/IIIC or IV NSCLC

537 enrolled

Neoplasm Metastasis

NCT05390528 2023-08-08

HLX301

30 enrolled

Lymphoid

Lymphoma, Neoplasm Metastasis

NCT03284502 2023-08-01

HM95573 in Combination With Either Cobimetinib or Cetuximab in Patients With Locally Advanced or Metastatic Solid Tumors

148 enrolled

Neoplasm Metastasis

NCT05268666 2023-06-15

A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors

126 enrolled

Neoplasm Metastasis

NCT03567720 2023-06-01

Tavo and Pembrolizumab With or Without Chemotherapy in Patients With Inoperable Locally Advanced or Metastatic TNBC

Phase 2 Unknown

65 enrolled

Breast

Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT03797391 2023-05-31

A Dose Escalation With Expansion Study of EMB-01 in Participants With Advanced/Metastatic Solid Tumors

186 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms

NCT05769075 2023-04-24

A Study of TY-2136b in Patients With Advanced Solid Tumors Harboring ALK, ROS1 or NTRK1-3 Alterations

282 enrolled

Neoplasm Metastasis

NCT04614740 2022-12-13

The Phase I/Phase II Clinical Study of VC004 in Patients With Localized Advanced/Metastatic Solid Tumors

115 enrolled

Neoplasm Metastasis

NCT03774979 2022-11-08

SHR-1701 in Subjects With Metastatic or Locally Advanced Solid Tumors

193 enrolled

Neoplasm Metastasis

NCT03491631 2022-11-04

Phase I Study of SHR9146 + SHR-1210 +/- Apatinib in Patients With Advanced Solid Tumors

23 enrolled

Neoplasm Metastasis, Neoplasms

NCT00986661 2022-11-02

A Study to Assess PV-10 Chemoablation of Cancer of the Liver

BreastDermatologicEndocrineGastrointestinalThoracic

78 enrolled

Uveal Melanoma, Breast Neoplasms, Carcinoid Tumor, Colonic Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT05150457 2022-09-27

Safety and Preliminary Efficacy of BNA035 in Patients With Advanced Solid Tumors

48 enrolled

Neoplasm Metastasis, Neoplasms, Recurrence

NCT04801095 2022-09-16

A Phase I Study of WM-S1-030 in Patients With Advanced Solid Tumors

GastrointestinalHead & NeckThoracic

100 enrolled

Head and Neck Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT02076646 2022-04-14

A Phase I/II Dose Escalation Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Dacarbazine for Patients With Metastatic Melanoma

96 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis

NCT03646071 2022-04-13

A Study of RX108 in Patients With Locally Advanced or Metastatic Solid Tumors

80 enrolled

Neoplasm Metastasis

NCT05315180 2022-04-07

A Phase 1，Open-label Study of BPI-421286 in Subjects With Advanced Solid Tumors

80 enrolled

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT05189717 2022-04-05

A Trial of HRS-8080 Tablets in Metastatic or Local Advanced Breast Cancer of Adults

156 enrolled

Neoplasm Metastasis

NCT03835949 2022-04-01

Study of TJ004309 in Combination With Atezolizumab (Tecentriq®) in Patients With Advanced or Metastatic Cancer

Neoplasm Metastasis

NCT05302843 2022-03-31

A Phase 1 Study of BPI-28592 in Subjects With Advanced Solid Tumors

40 enrolled

Neoplasm Metastasis

NCT05200273 2022-01-20

A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK114

30 enrolled

Neoplasm Metastasis, Neoplasms

NCT03710265 2021-11-22

SHR-1701 in Metastatic or Locally Advanced Solid Tumors

206 enrolled

Neoplasm Metastasis

NCT04859777 2021-09-16

A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors

70 enrolled

Neoplasm Metastasis, Neoplasms

NCT05028478 2021-08-31

A Study of CN202 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors or Hematologic Malignancies

Other hematologic neoplasm

164 enrolled

Neoplasm Metastasis, Hematologic Neoplasms

NCT04906733 2021-08-13

Cetuximab Sensitivity Correlation Between Patient-Derived Organoids and Clinical Response in Colon Cancer Patients.

Unknown

80 enrolled

Phase EARLY_PHASE1 Unknown

Colonic Neoplasms, Neoplasm Metastasis

NCT04674488 2020-12-19

TILs for Treatment of Metastatic or Recurrent Cervical Cancer

15 enrolled

Gynecologic

Uterine Cervical Neoplasms, Neoplasm Metastasis

NCT03896958 2020-12-04

PIONEER

Unknown

1,000 enrolled

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Adenocarcinoma of Lung, Adrenal Gland Neoplasms, Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Neoplasms, Unknown Primary, Neurologic Manifestations, Oligodendroglioma, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Uterine Neoplasms, Vulvar Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Thyroid Carcinoma, Anaplastic

NCT03468751 2020-06-01

Phase 1 Study of HLX10, a Monoclonal Antibody Targeting Programmed Death-1 (PD-1) in Patients With Advanced Solid Tumors

30 enrolled

Neoplasm Metastasis, Neoplasms

NCT04071184 2019-09-26

Study of Alofanib in Patients With Metastatic Gastric Cancer

50 enrolled

Neoplasm Metastasis, Stomach Neoplasms

NCT02077868 2019-09-10

IMPALA

540 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT03058809 2018-05-31

Evaluation of Viatar™ Oncopheresis System in Removing CTC From Whole Blood

100 enrolled

Neoplasm Metastasis

NCT01304797 2017-01-06

Safety and Pharmacokinetic Study of MM-302 in Patients With Advanced Breast Cancer

75 enrolled

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT02882659 2016-08-30

Dendritic Killer Cell-based Immunotherapy for Solid Tumors

18 enrolled

Carcinoma, Hepatocellular, Neoplasm Metastasis, Colorectal Neoplasms

NCT02352571 2016-07-06

Safety Study of GC1118 (Recombinant Human Anti-EGFR Antibody) in Patients With Advanced Solid Cancer

72 enrolled

Neoplasm Metastasis, Stomach Neoplasms, Colorectal Neoplasms

NCT01630733 2016-07-01

A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer

700 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00477906 2015-12-03

M-Vax + Low Dose Interleukin-2 Versus Placebo Vaccine in Metastatic Melanoma in Patients With Stage IV Melanoma

387 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis

NCT00688116 2014-09-18

Study of STA-9090, Administered Twice-Weekly in Patients With Solid Tumors

45 enrolled

Neoplasm Metastasis

NCT01140763 2010-08-30

Clinical Evaluation of Tissue Sampling Bias in Histologic Evaluation of Sentinel Lymph Nodes in Breast Cancer

Unknown

75 enrolled

Breast

Breast Diseases, Breast Neoplasms, Neoplasm Metastasis

NCT00787982 2010-01-01

Magnetic Resonance Imaging-Guided Laser Induced Thermal Therapy for Treatment of Metastatic Brain Tumors

20 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00448734 2009-01-21

A Study of Picoplatin and Docetaxel in Subjects With Prostate Cancer