Clinical Trials Browser

Phase 2 × Neoplasms, Germ Cell and Embryonal × 1 year × Clear all

Brain Neoplasms, Carcinoma, Ependymoma, Histiocytosis, Langerhans-Cell, Medulloblastoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Neuroblastoma, Pinealoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT03158064 2026-01-28

Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors

Phase 2 Active not recruiting

30 enrolled

Nonseminomatous germ cell tumor, Dysgerminoma, Neoplasms, Germ Cell and Embryonal, Germinoma, Seminoma

NCT04876456 2026-01-15

A Phase II Trial of Cabozantinib With Patients With Refractory GCTs

Phase 2 Active not recruiting

50 enrolled

Nonseminomatous germ cell tumor, Neoplasms, Germ Cell and Embryonal, Seminoma

NCT05634785 2026-01-09

CD30 CAR for CD30+ NSGCT

Phase 2 Completed

2 enrolled

Nonseminomatous germ cell tumor, Neoplasms, Germ Cell and Embryonal

NCT07188441 2025-09-23

Treatment of Newly Diagnosed Central Malignant Germ Cell Tumor People With Teniposide Injection Combined With Cisplatin.

Phase 2 Recruiting

40 enrolled

Neoplasms, Germ Cell and Embryonal

NCT06470464 2025-09-18

Thalidomide Combined With Chemotherapy in the Treatment of Relapsed or Refractory Yolk Sac Tumor

Phase 2 Completed

20 enrolled

Neoplasms, Germ Cell and Embryonal, Recurrence, Endodermal Sinus Tumor

NCT07121322 2025-08-13

DACT-GCT

Phase 2 Recruiting

33 enrolled

Neoplasms, Germ Cell and Embryonal

NCT06418789 2025-08-03

GERMAN

Phase 2 Recruiting

25 enrolled

Nonseminomatous germ cell tumor, Choriocarcinoma, Neoplasms, Germ Cell and Embryonal, Teratoma, Germinoma, Seminoma, Endodermal Sinus Tumor

NCT01873326 2025-07-03

Paclitaxel, Ifosfamide and Cisplatin (TIP) Versus Bleomycin, Etoposide and Cisplatin (BEP) for Patients With Previously Untreated Intermediate- and Poor-risk Germ Cell Tumors

Phase 2 Active not recruiting

92 enrolled

Neoplasms, Germ Cell and Embryonal

NCT06940804 2025-07-02

AVENTURINE

Phase 2 Withdrawn

Genitourinary

Testicular Germ Cell Tumor, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT04743310 2025-06-13

Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System

Phase 2 Completed

50 enrolled

CNS

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Neuroma, Acoustic, Pinealoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT04804007 2025-04-18

Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT

Phase 2 Recruiting

64 enrolled

Nonseminomatous germ cell tumor, Neoplasms, Germ Cell and Embryonal

Clinical Trials

AflacST1502

Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors

A Phase II Trial of Cabozantinib With Patients With Refractory GCTs

CD30 CAR for CD30+ NSGCT

Treatment of Newly Diagnosed Central Malignant Germ Cell Tumor People With Teniposide Injection Combined With Cisplatin.

Thalidomide Combined With Chemotherapy in the Treatment of Relapsed or Refractory Yolk Sac Tumor

DACT-GCT

GERMAN

Paclitaxel, Ifosfamide and Cisplatin (TIP) Versus Bleomycin, Etoposide and Cisplatin (BEP) for Patients With Previously Untreated Intermediate- and Poor-risk Germ Cell Tumors

AVENTURINE

Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System

Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT