Clinical Trials Browser

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Stomach Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Small Cell Lung Carcinoma

NCT03336606 2025-07-10

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

Phase 1 Active not recruiting

35 enrolled

DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Squamous Cell

NCT03935893 2025-07-10

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Phase 2 Recruiting

240 enrolled

DermatologicEndocrineGastrointestinalNETOther solid neoplasmSarcomaThoracic

Turcot syndrome, Mesothelioma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Neuroendocrine Tumors, Microsatellite Instability

NCT00076310 2025-06-26

OSI-774/Cisplatin/Taxotere in Head & Neck Squamous Cell Cancer

Phase 2 Active not recruiting

50 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT04908111 2025-06-13

A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1

Phase 1/2 Suspended

15 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Lung Neoplasms, Neoplasms, Neoplasms, Squamous Cell

NCT04496674 2025-04-23

2019-004849-32

Phase 1/2 Terminated

3 enrolled

Neoplasms, Squamous Cell

NCT04357873 2025-02-19

PEVOsq

Phase 2 Completed

112 enrolled

GastrointestinalGenitourinaryGynecologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Penile Neoplasms, Vulvar Neoplasms, Neoplasms, Squamous Cell

NCT05761132 2023-03-09

Apollo

Phase 2 Unknown

40 enrolled

Gynecologic

Vulvar Neoplasms, Neoplasms, Squamous Cell

NCT05252078 2022-12-16

ALTER-E005

Phase 2 Recruiting

30 enrolled

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Carcinoma, Squamous Cell, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Squamous Cell

NCT02837042 2022-06-21

Trial of Pembrolizumab for Advanced Penile Squamous Cell Carcinoma

Phase 2 Terminated

6 enrolled 10 charts

Genitourinary

Penile Neoplasms, Neoplasms, Squamous Cell

NCT02526953 2021-02-09

Efficacy Study of Chemoradiotherapy With or Without Paclitaxel in Squamous-cell Anal Carcinoma Patients

Phase 3 Unknown

314 enrolled

Gastrointestinal

Anus Diseases, Anus Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Neoplasms, Neoplasms, Squamous Cell

NCT04435938 2020-12-02

SHINE

Phase 2 Unknown

38 enrolled

Head & Neck

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT01111058 2020-04-07

Everolimus Versus Placebo in Head and Neck Cancer

Phase 2 Terminated

52 enrolled 13 charts

Head & Neck

Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT01581970 2019-09-11

Potentiation of Cetuximab by Tregs Depletion With CSA in Advanced Head & Neck Cancer

Phase 2 Completed

7 enrolled 9 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT01016769 2019-06-26

Temsirolimus + Weekly Paclitaxel + Carboplatin for Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)

Phase 1/2 Completed

48 enrolled 15 charts

Head & Neck

Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT00661427 2018-01-11

Cetuximab at Either 500 or 750 mg/m2 Every Other Week for Recurrent or Metastatic Head and Neck Squamous Cell Cancer

Phase 2 Completed

61 enrolled 8 charts

Head & Neck

Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT01721525 2017-10-25

Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)

Phase 1 Completed

10 enrolled

Head & Neck

Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT00591149 2017-06-14

Oxaliplatin and Docetaxel Followed by Cetuximab for Head and Neck Cancer

Phase 2 Terminated

16 enrolled 5 charts

Head & Neck

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasms, Neoplasms, Squamous Cell

NCT00815295 2014-12-08

Study of Sorafenib/Cetuximab in Head and Neck Cancer

Phase 1/2 Completed

31 enrolled 11 charts

Neoplasms, Squamous Cell

NCT00363441 2012-01-19

A Study of Conventional 3D Radiation vs. Intensity-Modulated Radiation in Squamous Cell Cancer of the Head and Neck

Phase 2/3 Withdrawn

Head & Neck

Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT00507858 2011-09-23

Pemetrexed (Alimta) in Patients With Head and Neck Squamous Cell Cancer

Phase 1 Completed

36 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

Clinical Trials

Cetuximab & Nivolumab in Patients With Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

Safety and Feasibility of Nivolumab-IRDye800CW in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC)

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial)

Using MC1R Genotype to Impact Melanoma Risk Behavior

AM-003

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

OSI-774/Cisplatin/Taxotere in Head & Neck Squamous Cell Cancer

A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1

2019-004849-32

PEVOsq

Apollo

ALTER-E005

Trial of Pembrolizumab for Advanced Penile Squamous Cell Carcinoma

Efficacy Study of Chemoradiotherapy With or Without Paclitaxel in Squamous-cell Anal Carcinoma Patients

SHINE

Everolimus Versus Placebo in Head and Neck Cancer

Potentiation of Cetuximab by Tregs Depletion With CSA in Advanced Head & Neck Cancer

Temsirolimus + Weekly Paclitaxel + Carboplatin for Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)

Cetuximab at Either 500 or 750 mg/m2 Every Other Week for Recurrent or Metastatic Head and Neck Squamous Cell Cancer

Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)

Oxaliplatin and Docetaxel Followed by Cetuximab for Head and Neck Cancer

Study of Sorafenib/Cetuximab in Head and Neck Cancer

A Study of Conventional 3D Radiation vs. Intensity-Modulated Radiation in Squamous Cell Cancer of the Head and Neck

Pemetrexed (Alimta) in Patients With Head and Neck Squamous Cell Cancer