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Recent Start date Enrollment

Neoplasms, Unknown Primary × cobimetinib × 1 year × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Tumor-Agnostic 1

Conditions

Melanoma 8 Neoplasms 6 Carcinoma, Non-Small-Cell Lung 5 Multiple Myeloma 3 Thyroid Carcinoma, Anaplastic 2 Thyroid Cancer, Papillary 2 Pancreatic Neoplasms 2 Ovarian Neoplasms 2 Neoplasms by Site 2 Neoplasms by Histologic Type 2 Lymphoma, Non-Hodgkin 2 Lung Neoplasms 2 Hematologic Neoplasms 2 Erdheim-Chester Disease 2 Xanthogranuloma, Juvenile 1 Thyroid Neoplasms 1 Skin Neoplasms 1 Pancreatic Adenocarcinoma 1 Neoplasms, Unknown Primary 1 Neoplasm Metastasis 1 Microsatellite Unstable Colorectal Cancer 1 Lymphoproliferative Disorders 1 Leukemia, Myelomonocytic, Chronic 1 Leukemia, Myeloid, Acute 1 Laryngeal Neoplasms 1 Inflammatory Breast Neoplasms 1 Histiocytosis, Sinus 1 Histiocytosis, Langerhans-Cell 1 Histiocytic Sarcoma 1 Histiocytic Disorders, Malignant 1

Interventions

pembrolizumab 2 atezolizumab 2 zenocutuzumab 1 sintilimab 1 pertuzumab 1 pemigatinib 1 olaparib 1 ivosidenib 1 ipatasertib 1 entrectinib 1 cobimetinib 1 alectinib 1 Whole Genome Sequencing 1 Vemurafenib 1 Transurethral Resection of Prostate 1 Specimen Handling 1 Sequence Analysis, RNA 1 Radiosurgery 1 Paclitaxel 1 Magnetic Resonance Spectroscopy 1 HhAntag691 1 Genetic Testing 1 Genetic Profile 1 Gemcitabine 1 Fluorodeoxyglucose F18 1 FAPI-46 1 Erlotinib Hydrochloride 1 Cisplatin 1 Carboplatin 1 Bevacizumab 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03498521 2025-11-19

CUPISCO

Hoffmann-La Roche

Phase 2 Completed

529 enrolled 16 charts

Neoplasms, Unknown Primary

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