Clinical Trials

170 enrolled

Classical hematologyDermatologicSarcoma

Neoplasms

NCT05256225 2026-03-18

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Phase 3 Recruiting

360 enrolled

Gynecologic

Neoplasms, Endometrial Neoplasms

NCT07005297 2026-03-18

Clinical Genetics Branch Eligibility Screening Survey

Not yet recruiting

1,000 enrolled

Cardiofaciocutaneous syndrome, Legius syndrome, Congenital Bone Marrow Failure Syndromes, Melanoma, Cutaneous Malignant, Chordoma, Fanconi Anemia, Melanoma, Neoplasms, Li-Fraumeni Syndrome, Pulmonary Blastoma, Costello Syndrome

NCT07416188 2026-03-18

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

Phase 1/2 Not yet recruiting

40 enrolled

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Nerve Tissue, Recurrence, Central Nervous System Neoplasms

NCT05026138 2026-03-16

Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)

850 enrolled

Infections, Neoplasms

NCT05588141 2026-03-13

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Phase 1/2 Recruiting

96 enrolled

Brain Neoplasms, Glioma, Neoplasms, Recurrence

NCT05909202 2026-03-13

A Nature-Based Virtual Reality (VR) Intervention in Family Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

Phase NA Recruiting

218 enrolled

Neoplasms

NCT04442425 2026-03-12

Machine Learning to Analyze Facial Imaging, Voice and Spoken Language for the Capture and Classification of Cancer/Tumor Pain

83 enrolled

Neoplasms

NCT00001163 2026-03-11

Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer

5,201 enrolled

Neoplasms

NCT00001823 2026-03-11

Evaluation for NCI Surgery Branch Clinical Research Protocols

DermatologicGastrointestinalGenitourinaryThoracic

7,000 enrolled

Urinary Bladder Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Colorectal Neoplasms

NCT00068003 2026-03-11

Harvesting Cells for Experimental Cancer Treatments

Enrolling by invitation

7,000 enrolled

BreastDermatologicGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms

NCT00092222 2026-03-11

Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

Phase 2 Active not recruiting

75 enrolled

Lymphoid

Multi-centric Castleman's Disease, Macular dystrophy, corneal type 1, Lymphadenopathy, Lymphoproliferative Disorders, Neoplasms, HIV Infections

NCT00341276 2026-03-11

Esophageal Cancer Genetics Studies

7,705 enrolled

Gastrointestinal

Esophageal Neoplasms, Neoplasms

NCT01109394 2026-03-11

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

CNSGenitourinaryOther solid neoplasmSarcoma

6,035 enrolled

Kidney Neoplasms, Neoplasms, Neuroblastoma, Retinoblastoma, Sarcoma

NCT02639325 2026-03-11

Tumor Related Epilepsy

100 enrolled

Brain Neoplasms, Epilepsy, Neoplasms, Seizures

NCT02851706 2026-03-11

Natural History of and Specimen Banking for People With Tumors of the Central Nervous System

1,214 enrolled

Astrocytoma, Brain Neoplasms, Glioma, Neoplasms, Spinal Cord Neoplasms

NCT03952624 2026-03-11

Patient-Centered Assessment of Symptoms and Outcomes

692 enrolled

Fatigue, Neoplasms, Fatigue Syndrome, Chronic

NCT04609072 2026-03-11

Connect for Cancer Prevention Study (Connect)

200,000 enrolled

Neoplasms

NCT00026884 2026-03-10

Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

5,950 enrolled

Genitourinary

Urinary Bladder Neoplasms, Kidney Neoplasms, Neoplasms, Neoplastic Syndromes, Hereditary

NCT00026650 2026-03-09

Evaluation of Late Effects and Natural History of Disease in Patients Treated With Radiotherapy

700 enrolled

Neoplasms

NCT00027326 2026-03-09

Collection of Blood and Urine From Patients Undergoing Radiation Therapy

Enrolling by invitation

1,000 enrolled

Carcinoma, Neoplasms

NCT01443468 2026-03-09

Clinical and Genetic Studies of Li-Fraumeni Syndrome

5,000 enrolled

Neoplasms, Li-Fraumeni Syndrome

NCT03366116 2026-03-09

5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

Phase 1 Recruiting

65 enrolled

Neoplasms

NCT04449549 2026-03-09

Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Phase 2 Recruiting

82 enrolled

Neoplasms

NCT00001186 2026-03-06

Psychological Benefits of a Normalized Camping Experience for Children With Cancer

5,000 enrolled

Neoplasms

NCT00033137 2026-03-06

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

950 enrolled

Genitourinary

Kidney Neoplasms, Neoplasms, Pneumothorax

NCT00339495 2026-03-06

Prostate Lung Colorectal and Ovarian (PLCO) Cancer Screening Trial

154,900 enrolled

Death, Neoplasms

NCT00352924 2026-03-06

Agriculture Health Study

GenitourinaryLymphoidPlasma cell

89,655 enrolled

Lymphoma, Multiple Myeloma, Neoplasms, Prostatic Neoplasms

NCT01441089 2026-03-06

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

BreastGenitourinaryGynecologicLymphoidThoracic

1,100 enrolled

Breast Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms

NCT01445483 2026-03-06

Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain Metastases

35 enrolled

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT02423057 2026-03-06

Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors

Phase 1 Completed

27 enrolled

Neoplasms

NCT04450927 2026-03-06

Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors

Enrolling by invitation

10,000 enrolled

Hematologic Diseases, Neoplasms

NCT05350761 2026-03-06

Rare Tumors and Cancer Predisposition in Individuals and Families

500 enrolled

Neoplasms

NCT04267861 2026-03-04

M7824 Related Adverse Effects in Adults With Cancer

232 enrolled

Dermatologic

Neoplasms, Skin Neoplasms

NCT00006518 2026-02-25

Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer