NCT03785249 2025-09-30
Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1
Mirati Therapeutics Inc.
Phase 1/2 Active not recruiting
Clinical Trials
16 trialsNCT00748709 2025-02-11
Phase II Trial of BIBW 2992 (Afatinib) in Genetically Pre-screened Cancers With EGFR and/or HER2 Gene Amplification.
Boehringer Ingelheim
Phase 2 Terminated
NCT01214616 2025-02-07
BIBW 2992 (Afatinib) and Vinorelbine in Japanese Patients With Advanced Solid Tumours
Boehringer Ingelheim
Phase 1 Completed
NCT02171650 2025-01-23
BIBW 2992 in Patients With Advanced Solid Tumors
Boehringer Ingelheim
Phase 1 Completed
NCT01206816 2019-02-01
An Open Label Phase I Dose Escalation Trial of Intravenous BI 6727 (Volasertib)in Combination With Oral BIBW 2992 (Afatinib) in Patients With Advanced Solid Tumours
Boehringer Ingelheim
Phase 1 Completed
NCT02020577 2017-06-22
Trial of Afatinib (BIBW 2992) + Cetuximab in Advanced Solid Tumours
Boehringer Ingelheim
Phase 1 Completed
NCT00809133 2016-03-14
Trial Exploring Afatinib (BIBW 2992) + Paclitaxel (Part A), Afatinib + Paclitaxel + Bevacizumab (Part B), Afatinib + Carboplatin (Part C) and Afatinib+ Paclitaxel +Carboplatin(Part D) in Patients With Advanced Solid Tumours
Boehringer Ingelheim
Phase 1 Completed
NCT02171663 2015-01-28
Dose Escalation Study of BIBW 2992 in Patients With Advanced Solid Tumors
Boehringer Ingelheim
Phase 1 Completed
NCT02171637 2014-06-24
Dose Escalation Study of Oral Treatment With BIBW 2992 in Patients With Advanced Solid Tumors
Boehringer Ingelheim
Phase 1 Completed
NCT02171676 2014-06-24
BIBW 2992 After Administration of Docetaxel in Patients With Advanced Solid Tumors
Boehringer Ingelheim
Phase 1 Completed
NCT02171702 2014-06-24
Dose Escalation Study of Oral Treatment With BIBW 2992 in Patients With Advanced Solid Tumours
Boehringer Ingelheim
Phase 1 Completed
NCT02171728 2014-06-24
Dose Escalation Study of Continuous Once-daily Oral Treatment With BIBW 2992 in Patients With Advanced Solid Tumors
Boehringer Ingelheim
Phase 1 Completed
NCT02171741 2014-06-24
Dose Escalation Trial of BIBW 2992 Administration in Combination With Docetaxel in Patients With Advanced Solid Tumors
Boehringer Ingelheim
Phase 1 Completed
NCT01169675 2014-06-09
BIBW 2992 (Afatinib) in Combination With Pemetrexed in Advanced Solid Tumours
Boehringer Ingelheim
Phase 1 Completed
NCT00875433 2013-12-30
Afatinib (BIBW 2992) QTcF Trial in Patients With Relapsed or Refractory Solid Tumours
Boehringer Ingelheim
Phase 2 Completed
NCT00730821 2009-08-21
Phase I of BIBW 2992/BIBF 1120 Combination Therapy in Solid Tumors
Boehringer Ingelheim
Phase 1 Completed