Clinical Trials Browser

Urogenital Diseases, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Prostatic Diseases, Prostatic Neoplasms, Urogenital Neoplasms, Male Urogenital Diseases

NCT06178614 2026-03-13

A Study of JNJ-87890387 for Advanced Solid Tumors

Phase 1 Recruiting

200 enrolled

Tumor-Agnostic

Neoplasms

NCT03366116 2026-03-09

5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

Phase 1 Recruiting

65 enrolled

Tumor-Agnostic

Neoplasms

NCT06533059 2026-03-09

A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors

Phase 1 Recruiting

110 enrolled

BreastGenitourinaryGynecologic

Breast Neoplasms, Uterine Cervical Neoplasms, Genital Neoplasms, Female, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06835569 2026-03-09

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

Phase 1 Recruiting

188 enrolled

GastrointestinalThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06555744 2026-03-06

A Study of ZW191 in Participants With Solid Tumors

Phase 1 Recruiting

145 enrolled

Tumor-Agnostic

Neoplasms

NCT07371104 2026-03-05

Bioequivalence Study of DWZ2501 in Patients With Advanced BRCA-mutated High-grade Ovarian Cancer

Phase 1 Recruiting

40 enrolled

Gynecologic

Neoplasms, Ovarian Neoplasms

NCT05538130 2026-03-04

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

Phase 1 Recruiting

124 enrolled

CNSDermatologicHead & NeckThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioma, Melanoma, Neoplasms, Thyroid Neoplasms

NCT06713369 2026-03-04

AZD5305

Phase 1 Recruiting

8 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT07447856 2026-03-04

A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain

Phase 1 Recruiting

150 enrolled

Cancer Pain, Neoplasms, Pain

NCT03391778 2026-03-03

Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

Phase 1 Recruiting

250 enrolled

Tumor-Agnostic

Neoplasms

NCT05873686 2026-03-03

A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

Phase 1 Recruiting

140 enrolled

GenitourinaryOther solid neoplasmThoracic

Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Kidney Neoplasms, Mesothelioma, Neoplasms

NCT07046559 2026-03-03

A Single- and Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY4066708 in Healthy Participants

Phase 1 Recruiting

104 enrolled

Tumor-Agnostic

Neoplasms

NCT07321106 2026-03-03

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

Phase 1 Recruiting

80 enrolled

Gastrointestinal

Colonic Neoplasms, Neoplasms, Colorectal Neoplasms

NCT05382559 2026-03-02

A Study of ASP3082 in Adults With Advanced Solid Tumors

Phase 1 Recruiting

681 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT06657144 2026-03-02

A Study of CHS-114 in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

Phase 1 Recruiting

154 enrolled

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT06884618 2026-03-02

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

Phase 1 Recruiting

345 enrolled

Tumor-Agnostic

Neoplasms

NCT06910657 2026-03-02

IDOV-Immune for Advanced Solid Tumors

Phase 1 Recruiting

78 enrolled

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Adrenal Gland Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Vaccinia, Colorectal Neoplasms

NCT03830320 2026-02-27

Positron Emission Tomography (PET) Imaging of Thrombosis

Phase 1 Recruiting

165 enrolled

COVID-19, Atrial Fibrillation, Neoplasms, Thrombosis

NCT06759649 2026-02-27

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

Phase 1 Recruiting

200 enrolled

Tumor-Agnostic

Neoplasms

NCT07382817 2026-02-27

Phase 1 Study of JV-394 Autologous Anti-CD94 CAR T for r/r CD94+ T/NK Cell Neoplasms

Phase 1 Recruiting

33 enrolled

Lymphoid

Neoplasms, Lymphoma, T-Cell, Lymphoma, Extranodal NK-T-Cell

NCT06104488 2026-02-25

A Study of Avutometinib for People With Solid Tumor Cancers

Phase 1 Recruiting

23 enrolled

CNS

Brain Neoplasms, Neoplasms, Neuroblastoma, Central Nervous System Neoplasms, Neurofibroma, Plexiform

NCT07156136 2026-02-25

Study of IMC-P115C in Advanced PRAME-Positive Cancers

Phase 1 Recruiting

140 enrolled

Tumor-Agnostic

Neoplasms

NCT07094204 2026-02-23

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Phase 1 Recruiting

364 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT05647122 2026-02-20

EGRET

Phase 1 Recruiting

403 enrolled

GastrointestinalHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Neoplasms, Colorectal Neoplasms

NCT06959706 2026-02-20

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors

Phase 1 Recruiting

50 enrolled

Tumor-Agnostic

Carcinoma, Neoplasms

NCT06333951 2026-02-19

AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).

Phase 1 Recruiting

500 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT04485013 2026-02-18

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

Phase 1 Recruiting

240 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06524570 2026-02-18

iFOCUS

Phase 1 Recruiting

24 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT07197554 2026-02-18

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

Phase 1 Recruiting

171 enrolled

GastrointestinalGynecologicSarcoma

Biliary Tract Neoplasms, Carcinoma, Hepatocellular, Neoplasms, Sarcoma, Ewing, Endometrial Neoplasms

NCT03911388 2026-02-17

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Phase 1 Recruiting

24 enrolled

CNSSarcoma

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT06885697 2026-02-17

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Phase 1 Recruiting

100 enrolled

GastrointestinalGynecologicOther solid neoplasmThoracic

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

NCT07238075 2026-02-17

ADCX-020 for the Treatment of Patients With Locally Advanced or Metastatic Cancers

Phase 1 Recruiting

290 enrolled

Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT06311578 2026-02-13

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

Phase 1 Recruiting

96 enrolled

Tumor-Agnostic

Neoplasms

NCT05618028 2026-02-12

Study to Evaluate Adverse Events and Change in Disease Activity in Adult Participants With B-Cell Malignancies Receiving Oral ABBV-525 Tablets

Phase 1 Recruiting

150 enrolled

LymphoidOther hematologic neoplasm

Lymphoma, Non-Hodgkin, Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse

NCT05650632 2026-02-12

A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

Phase 1 Recruiting

210 enrolled

Plasma cell

Multiple Myeloma, Neoplasms

NCT06360354 2026-02-12

MTAPESTRY 103

Phase 1 Recruiting

350 enrolled

Gastrointestinal

Neoplasms, Pancreatic Neoplasms

NCT06440005 2026-02-11

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Phase 1 Recruiting

80 enrolled

BreastGastrointestinalGenitourinarySarcoma

Breast Neoplasms, Hemangiosarcoma, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT06607939 2026-02-10

OR2-01

Phase 1 Recruiting

36 enrolled

Tumor-Agnostic

Neoplasms

NCT07258836 2026-02-10

A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer

Phase 1 Recruiting

41 enrolled

Tumor-Agnostic

Neoplasms

NCT06487624 2026-02-05

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

Phase 1 Recruiting

50 enrolled

Lymphoid

Camurati-Engelmann Syndrome, Hodgkin Disease, Neoplasms

Clinical Trials

KEYNOTE-E12

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

A Study of ASP1002 in Adults for Treatment of Solid Tumors

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

PNOC028

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

MK-8294-001

STRIKE-001

A Study of JNJ-87890387 for Advanced Solid Tumors

5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

A Study of ZW191 in Participants With Solid Tumors

Bioequivalence Study of DWZ2501 in Patients With Advanced BRCA-mutated High-grade Ovarian Cancer

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

AZD5305

A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain

Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

A Single- and Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY4066708 in Healthy Participants

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

A Study of ASP3082 in Adults With Advanced Solid Tumors

A Study of CHS-114 in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

IDOV-Immune for Advanced Solid Tumors

Positron Emission Tomography (PET) Imaging of Thrombosis

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

Phase 1 Study of JV-394 Autologous Anti-CD94 CAR T for r/r CD94+ T/NK Cell Neoplasms

A Study of Avutometinib for People With Solid Tumor Cancers

Study of IMC-P115C in Advanced PRAME-Positive Cancers

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

EGRET

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors

AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

iFOCUS

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

ADCX-020 for the Treatment of Patients With Locally Advanced or Metastatic Cancers

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

Study to Evaluate Adverse Events and Change in Disease Activity in Adult Participants With B-Cell Malignancies Receiving Oral ABBV-525 Tablets

A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

MTAPESTRY 103

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

OR2-01

A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors