Clinical Trials Browser

Interventional × Nervous System Diseases × Clear all

Alzheimer Disease, Mental Disorders, Brain Diseases, Central Nervous System Diseases, Dementia, Inflammation, Nervous System Diseases, Neurodegenerative Diseases, Neurocognitive Disorders, Tauopathies

NCT03911388 2026-02-17

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Phase 1 Recruiting

24 enrolled

CNSSarcoma

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT05443321 2026-01-23

Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes

Phase NA Enrolling by invitation

1,006 enrolled

GastrointestinalGenitourinary

Arrhythmias, Cardiac, Asthma, Cardiovascular Diseases, Gastrointestinal Diseases, Heart Failure, Hematologic Diseases, Infections, Kidney Diseases, Nervous System Diseases, Rheumatic Diseases, Shock, Urologic Diseases, Critical Illness, Renal Insufficiency

NCT07343297 2026-01-15

ASQ-CT

Phase NA Not yet recruiting

293 enrolled

Heart Diseases, Neoplasms, Nervous System Diseases

NCT06468176 2025-12-19

FREEDOME

Phase NA Recruiting

187 enrolled

CNS

Glioma, Neoplasms, Nervous System Diseases

NCT00690196 2025-11-10

Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms

Phase NA Active not recruiting

90 enrolled

Mental Disorders, Sleep Initiation and Maintenance Disorders, Nervous System Diseases, Sleep Wake Disorders, Dyssomnias

NCT07098806 2025-08-01

CA2024-LM-001

Phase 1 Recruiting

24 enrolled

CNS

Meningeal Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Nervous System Diseases, Nervous System Neoplasms, Pathologic Processes, Central Nervous System Neoplasms, Meningeal Carcinomatosis

NCT04865679 2025-05-02

REPOSE-XL℠

Phase NA Active not recruiting

15 enrolled

Nervous System Diseases, Neuralgia, Neuroma, Peripheral Nervous System Diseases, Trauma, Nervous System, Peripheral Nerve Injuries

NCT03150862 2025-02-04

A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma

Phase 1/2 Completed

116 enrolled 31 charts

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Nervous System Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Gliosarcoma

NCT04796935 2024-06-11

A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control

Phase NA Completed

95 enrolled 25 charts

CNS

Central Nervous System Infections, Neoplasms, Nervous System Diseases, Pseudotumor Cerebri, Post-Dural Puncture Headache

NCT06406127 2024-05-09

Effect of Alpha Lipoic Acid on Chemotherapy Induced Neurological Changes in Breast Cancer Patients

Phase 4 Recruiting

92 enrolled

Breast

Breast Neoplasms, Nervous System Diseases

NCT06330298 2024-04-16

T-ScEmo4ALL

Phase NA Recruiting

84 enrolled

CNS

Brain Neoplasms, Multiple Sclerosis, Nervous System Diseases, Social Behavior, Stroke

NCT05321498 2023-09-28

Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation

Phase 2 Withdrawn

CNS

Alzheimer Disease, Mental Disorders, Brain Diseases, Central Nervous System Diseases, Dementia, Inflammation, Nervous System Diseases, Neurodegenerative Diseases, Tauopathies, Cognitive Dysfunction

NCT01290692 2023-07-03

Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma

Phase 2 Completed

14 enrolled 11 charts

CNS

Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Glioblastoma, Glioma, Neoplasms, Nervous System Diseases, Nervous System Neoplasms, Central Nervous System Neoplasms

NCT01081223 2023-06-01

Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma

Phase 1/2 Completed

12 enrolled 11 charts

CNS

Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Glioblastoma, Glioma, Neoplasms, Nervous System Diseases, Nervous System Neoplasms, Central Nervous System Neoplasms

NCT02798406 2021-07-15

CAPTIVE

Phase 2 Completed

49 enrolled

CNSSarcoma

Brain Neoplasms, Disease, Glioblastoma, Glioma, Neoplasms, Neoplasms, Nerve Tissue, Nervous System Diseases, Neuroectodermal Tumors, Neoplasms, Neuroepithelial, Gliosarcoma

NCT03650452 2021-02-18

ELEKTRA

Phase 2 Completed

141 enrolled 24 charts

CNS

CDKL5 deficiency disorder, Brain Diseases, Central Nervous System Diseases, Epilepsy, Epilepsies, Myoclonic, Nervous System Diseases, Seizures, Spasms, Infantile, Tuberous Sclerosis, Hypoxia-Ischemia, Brain, Malformations of Cortical Development, Lennox Gastaut Syndrome

NCT01386580 2015-01-22

An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.

Phase 1/2 Completed

84 enrolled

BreastCNSDermatologicThoracic

Brain Diseases, Brain Neoplasms, Breast Neoplasms, Central Nervous System Diseases, Glioma, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Neoplastic Processes, Nervous System Diseases, Nervous System Neoplasms, Pathologic Processes, Central Nervous System Neoplasms

NCT01210716 2013-09-23

Evaluation of Therapeutic Plasma Exchange (TPE) Procedure Using the AMICUS Device

Phase 3 Completed

37 enrolled 7 charts

Genitourinary

Autoimmune Diseases, Hematologic Diseases, Kidney Diseases, Nervous System Diseases, Paraproteinemias

NCT00643890 2012-02-22

Study of AAV-GAD Gene Transfer Into the Subthalamic Nucleus for Parkinson's Disease

Phase 2 Terminated

44 enrolled

CNS

Basal Ganglia Diseases, Brain Diseases, Central Nervous System Diseases, Movement Disorders, Nervous System Diseases, Parkinson Disease, Neurodegenerative Diseases, Parkinsonian Disorders, Ganglion Cysts

Clinical Trials

An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes

ASQ-CT

FREEDOME

Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms

CA2024-LM-001

REPOSE-XL℠

A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma

A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control

Effect of Alpha Lipoic Acid on Chemotherapy Induced Neurological Changes in Breast Cancer Patients

T-ScEmo4ALL

Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation

Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma

Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma

CAPTIVE

ELEKTRA

An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.

Evaluation of Therapeutic Plasma Exchange (TPE) Procedure Using the AMICUS Device

Study of AAV-GAD Gene Transfer Into the Subthalamic Nucleus for Parkinson's Disease