Clinical Trials Browser

OTHER × Interventional × Neurofibromatosis 1 × Clear all

NCT06188741 2026-03-12

NF114

Phase 2 Recruiting

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT06502171 2026-03-12

NF113

Phase 1 Not yet recruiting

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT06934928 2026-03-05

Assessing the Efficacy of Repeat, Monthly Treatments of Alexandrite Laser for NF1-associated Cutaneous Neurofibromas (cNFs)

Phase NA Suspended

Neurofibromatosis 1, Neurofibromatoses

NCT07233408 2026-02-27

Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy

Phase NA Recruiting

Neurofibromatosis 1, Neurofibromatoses

NCT07102394 2026-02-17

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

Phase 1 Recruiting

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT05253131 2026-02-11

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

Phase 2 Not yet recruiting

Neurofibromatosis 1, Sarcoma, Neurofibrosarcoma

NCT05363267 2026-01-13

NF-1, Nutraceutical Intervention

Phase 1 Active not recruiting

Neurofibromatosis 1

NCT03406208 2025-12-24

Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing

Phase NA Completed

Schwannomatosis, Behavior, Neurofibromatosis 1, Neurofibromatosis 2, Neurofibromatoses

NCT06132165 2025-11-21

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Phase 1 Completed

Neurofibromatosis 1

NCT06300502 2025-11-20

Assessing the Efficacy of Repeat, Monthly Treatments of Deoxycholate for NF1 Associated Cutaneous Neurofibromas (cNFs)

Phase 1 Enrolling by invitation

Neurofibroma, Neurofibromatosis 1

NCT06262113 2025-10-03

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

Phase NA Recruiting

Neurofibromatosis 1, Neurofibromatoses

NCT04763109 2025-09-09

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence

Phase NA Recruiting

Neurofibromatosis 1

NCT04481035 2025-07-31

NF1NAC

Phase 2 Completed

5 enrolled 10 charts

Neurofibromatosis 1

NCT05735717 2025-07-24

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Phase 2 Recruiting

CNSClassical hematologyLymphoidOther hematologic neoplasm

Chromosome 7, monosomy, Anemia, Refractory, with Excess of Blasts, Chromosome Aberrations, Influenza, Human, Neurofibromatosis 1, Leukemia, Myeloid, Acute, beta-Thalassemia, Neoplasm, Residual, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

NCT07077408 2025-07-22

iCanCope With NF: Innovating an Efficacious Digital Self-management and Transitional Care Program for Adolescents With Neurofibromatosis

Phase NA Not yet recruiting

Neurofibromatosis 1

NCT00624234 2025-07-08

Neurobiology and Treatment of Reading Disability in NF-1

Phase NA Completed

184 enrolled 10 charts

Dyslexia, Learning Disabilities, Neurofibromatosis 1

NCT06735820 2025-07-03

MEKMDM2

Phase 1/2 Not yet recruiting

Neurofibromatosis 1, Neurofibrosarcoma

NCT02964884 2025-06-24

Interventions for Reading Disabilities in NF1

Phase 2 Active not recruiting

Dyslexia, Learning Disabilities, Neurofibromatosis 1

NCT02728388 2025-05-08

Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II

Phase 2 Recruiting

Neurofibroma, Neurofibromatosis 1

NCT03231306 2025-05-02

NF108-BINI

Phase 2 Completed

45 enrolled 8 charts

Neurofibroma, Neurofibromatosis 1, Peripheral Nervous System Neoplasms, Neurofibromatoses, Neurofibroma, Plexiform

NCT04561765 2025-03-30

Innovation in the Treatment of Persistent Pain in Adults With NF1: Implementation of the iCanCope Mobile Application- Clinical Trial

Phase NA Completed

122 enrolled 21 charts

Neurofibromatosis 1, Chronic Pain

NCT05196854 2025-02-24

Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1

Phase NA Completed

Hypertension, Neurofibromatosis 1, Neurofibromatoses

NCT04730583 2025-02-21

Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

Phase 1 Completed

Neurofibromatosis 1

NCT06120036 2025-02-21

Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Phase 1 Completed

Neurofibromatosis 1

NCT06763315 2025-01-08

LS-NF1PNs

Phase 2 Not yet recruiting

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT05849662 2024-11-12

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Phase 1/2 Recruiting

CNSOther hematologic neoplasm

Neurofibromatosis 1, Leukemia, Myelomonocytic, Juvenile

NCT04481048 2024-10-09

DoDNAC

Phase 2 Active not recruiting

Neurofibromatosis 1

NCT06620354 2024-10-01

Clinical Study on the Treatment of Type I Neurofibromatosis With Smeitinib Hydrosulfate Capsule

Phase 2 Not yet recruiting

Neurofibromatosis 1

NCT06621082 2024-10-01

The Clinical Study of the Treatment of Patients With Type I Neurofibromatosis With Smetinib Hydrosulfate Capsule

Phase 2 Not yet recruiting

Neurofibromatosis 1

NCT02700230 2024-09-27

Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery

Phase 1 Completed

Neurofibromatosis 1, Neurofibrosarcoma

NCT05438290 2024-05-06

DPCP to Treat Cutaneous Neurofibromas Associated With NF1

Phase 1 Completed

Neurofibromatosis 1, Neurofibromatoses

NCT03741101 2024-04-11

plexifpc

Phase 2 Active not recruiting

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT03433183 2023-12-26

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Phase 2 Completed

Neurofibromatosis 1, Neurofibrosarcoma

NCT02332902 2023-12-20

DCLNF1

Phase 2 Completed

24 enrolled 4 charts

Neurofibroma, Neurofibromatosis 1

NCT03504501 2023-11-30

SynCoRAS

Phase 2 Terminated

Cognition Disorders, Neurofibromatosis 1, Noonan Syndrome

NCT03363217 2023-11-27

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

Phase 2 Active not recruiting

Brain Neoplasms, Glioma, Neurofibromatosis 1, Neurofibroma, Plexiform

NCT05377008 2023-09-22

OPTIMAL-SSI

Phase NA Completed

Neurofibromatosis 1, Neurofibromatoses

NCT00846430 2023-08-30

Medical Treatment of "High-Risk" Neurofibromas

Phase 2 Completed

9 enrolled 9 charts

Neurofibroma, Neurofibromatosis 1

NCT01968590 2022-05-25

VitDBoneNF1

Phase 2 Terminated

Neurofibromatosis 1

NCT02944032 2022-03-03

COGTRAIN

Phase NA Completed

Neurofibromatosis 1

NCT04991428 2021-08-05

Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1

Phase NA Completed

Neurofibromatosis 1

NCT04856514 2021-04-27

Open Trial of Telehealth Group for Improving Peer Relationships (PEERS) in NF1

Phase NA Unknown

Neurofibromatosis 1, Social Skills

NCT04860362 2021-04-26

Pilot Randomized Control Trial of Telehealth Group for Improving Peer Relationships (PEERS) in NF1

Phase NA Unknown

Neurofibromatosis 1, Social Skills

NCT03826940 2021-04-02

ASD/NF1inhib

Phase NA Completed

Autism Spectrum Disorder, Inhibition, Psychological, Neurofibromatosis 1

NCT01058330 2021-03-23

Effects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1

Phase NA Completed

Neurofibromatosis 1

NCT03672838 2021-03-18

A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)

Phase NA Completed

Neurofibromatosis 1, Neurofibromatosis 2

NCT03820778 2021-03-02

Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1

Phase NA Active not recruiting

Neurofibromatosis, type 4, of Riccardi, Neurofibroma, Neurofibromatosis 1, Neurofibroma, Plexiform

NCT01125046 2021-01-22

Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas

Phase 2 Completed

50 enrolled 13 charts

Brain Neoplasms, Ependymoma, Meningioma, Neurofibromatosis 1, Neuroma, Acoustic, Neurofibromatosis 2

NCT02387840 2021-01-12

Feasibility and Clinically Application of Magnetic Resonance Fingerprinting

Phase NA Terminated

35 enrolled 15 charts

Brain Neoplasms, Glioma, Neoplasms, Neurofibromatosis 1

NCT03981510 2020-11-25

Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation

Phase NA Unknown

CNSLymphoidOtherOther hematologic neoplasm

Constipation, Neurofibromatosis 1, Precursor Cell Lymphoblastic Leukemia-Lymphoma