Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1
Completed
17 enrolled
Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)
Completed
313 enrolled
Precision Medicine for Neurocutaneous Syndromes in Western China
Completed
1,200 enrolled
Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing
Phase NA Completed
228 enrolled
Evaluating Genetic Modifiers of Cutaneous Neurofibromas in Adults With Neurofibromatosis Type 1
Completed
1,046 enrolled
Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas
Phase 1 Completed
13 enrolled
NEF-1
Completed
30 enrolled
NF1NAC
Phase 2 Completed
5 enrolled 10 charts
Neurobiology and Treatment of Reading Disability in NF-1
Phase NA Completed
184 enrolled 10 charts
Evaluating Mitochondrial Dysfunction in Patients With Neurofibromatosis Type 1
Completed
55 enrolled 19 charts
NF108-BINI
Phase 2 Completed
45 enrolled 8 charts
Innovation in the Treatment of Persistent Pain in Adults With NF1: Implementation of the iCanCope Mobile Application- Clinical Trial
Phase NA Completed
122 enrolled 21 charts
Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1
Phase NA Completed
54 enrolled
Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas
Phase 1 Completed
34 enrolled
Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas
Phase 1 Completed
20 enrolled
Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma
Phase 2 Completed
75 enrolled 17 charts
MicroRNAs in Patients With Neurofibromatosis Type 1
Completed
9 enrolled
Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery
Phase 1 Completed
9 enrolled
Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)
Completed
296 enrolled
Analysis of Data Collected From Individuals Administered Neurobehavioral Assessments
Completed
598 enrolled
DPCP to Treat Cutaneous Neurofibromas Associated With NF1
Phase 1 Completed
17 enrolled
Systematically Assessing Changes in Plexiform Neurofibroma Related Disfigurement From Photographs of Subjects With Neurofibromatosis Type 1 on a Phase 2 Clinical Trial
Completed
52 enrolled
SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors
Phase 2 Completed
21 enrolled
DCLNF1
Phase 2 Completed
24 enrolled 4 charts
Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma
Phase 2 Completed
11 enrolled 11 charts
OPTIMAL-SSI
Phase NA Completed
38 enrolled
Medical Treatment of "High-Risk" Neurofibromas
Phase 2 Completed
9 enrolled 9 charts
Frameshift Peptides of Children With NF1
Completed
60 enrolled
NFX-179 Topical Gel Treatment in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)
Phase 2 Completed
48 enrolled 14 charts
Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain
Phase 3 Completed
66 enrolled 17 charts
Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors
Phase 1 Completed
29 enrolled
COGTRAIN
Phase NA Completed
103 enrolled
Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1
Phase NA Completed
31 enrolled
ASD/NF1inhib
Phase NA Completed
16 enrolled
Effects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1
Phase NA Completed
36 enrolled
A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)
Phase NA Completed
33 enrolled
Whole-body Vibration in Children With Neurofibromatosis Type 1
Phase NA Completed
30 enrolled
Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas
Phase 2 Completed
50 enrolled 13 charts
Eligibility Screening for a NCI Pediatric Oncology Branch Research Study
Completed
1,720 enrolled
Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I
Completed
645 enrolled
Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas
Phase 1 Completed
9 enrolled
Genetic Evaluation of NF1 and Scoliosis Patients
Completed
59 enrolled
NF1TD
Completed
395 enrolled
Multi-center Project: Spinal Abnormalities in Neurofibromatosis Type1 (NF1) Patients
Completed
300 enrolled
Internet Support Group for Parents of a Child With Neurofibromatosis Type 1
Completed
33 enrolled
MEK Inhibitor
Phase 2 Completed
19 enrolled 14 charts
A Study to Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male Participants
Phase 1 Completed
24 enrolled
Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors
Phase 2 Completed
48 enrolled 10 charts
Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas
Phase 2 Completed
23 enrolled 9 charts
Spine
Completed
112 enrolled