Clinical Trials Browser

Rasmussen subacute encephalitis, Autoimmune Diseases, Myasthenia Gravis, Neuromyelitis Optica, Lambert-Eaton Myasthenic Syndrome, Stiff-Person Syndrome, Autoimmune Diseases of the Nervous System, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating, Vasculitis, Central Nervous System, Opsoclonus-Myoclonus Syndrome

NCT07392528 2026-02-11

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/ BCMA（QT-019C） in Patients With r/ r Neurological Autoimmune Diseases

Phase EARLY_PHASE1 Not yet recruiting

15 enrolled

Multiple Sclerosis, Myasthenia Gravis, Neuromyelitis Optica

NCT07333196 2026-01-21

Tongji NADs Cohort

Not yet recruiting

1,550 enrolled

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease, Multiple Sclerosis, Myasthenia Gravis, Myositis, Neuromyelitis Optica, Autoimmune Diseases of the Nervous System, Guillain-Barre Syndrome, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT01623076 2026-01-06

The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders

Active not recruiting

150 enrolled

Myelitis, Transverse, Neuromyelitis Optica, Optic Neuritis

NCT06939166 2025-12-15

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/B Cell Maturation Antigen （CD19/BCMA） in Patients With r/r Neurological Autoimmune Diseases

Phase EARLY_PHASE1 Recruiting

12 enrolled

Multiple Sclerosis, Myasthenia Gravis, Neuromyelitis Optica, Autoimmune Diseases of the Nervous System, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT00445367 2025-10-02

Biobank For MS And Other Demyelinating Diseases

Active not recruiting

3,226 enrolled

Encephalomyelitis, Acute Disseminated, Multiple Sclerosis, Myelitis, Transverse, Neuromyelitis Optica, Optic Neuritis

NCT07022197 2025-06-15

Safety and Efficacy of BAFF-R CART for Refractory Neuroimmune Diseases

Phase 1/2 Recruiting

27 enrolled

Myasthenia Gravis, Myositis, Neuromyelitis Optica, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT06941584 2025-04-24

NAD-AIRE

Recruiting

40 enrolled

Myasthenia Gravis, Neuromyelitis Optica, Polyendocrinopathies, Autoimmune, Autoimmune Diseases of the Nervous System, Isaacs Syndrome

NCT06485232 2025-01-01

Universal CAR-T Cells in Patients with Refractory Autoimmune Diseases of the Nervous System.

Phase EARLY_PHASE1 Not yet recruiting

25 enrolled

Multiple Sclerosis, Myasthenia Gravis, Neuromyelitis Optica, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT05017142 2024-12-16

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Recruiting

500 enrolled

CNS

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease, Encephalitis, Encephalomyelitis, Acute Disseminated, Multiple Sclerosis, Myelitis, Transverse, Neuromyelitis Optica, Optic Neuritis, Autoimmune Diseases of the Nervous System, Vasculitis, Central Nervous System, Lupus Vasculitis, Central Nervous System, Anti-N-Methyl-D-Aspartate Receptor Encephalitis

NCT06502015 2024-11-20

Biomarkers in Autoimmune Disease of Nervous System

Recruiting

50,000 enrolled

Autoimmune Diseases, Encephalomyelitis, Acute Disseminated, Multiple Sclerosis, Myasthenia Gravis, Myositis, Neuromyelitis Optica, Stiff-Person Syndrome, Autoimmune Diseases of the Nervous System, Guillain-Barre Syndrome, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT03942952 2023-09-05

SONICS

Completed

49 enrolled

Encephalomyelitis, Acute Disseminated, Multiple Sclerosis, Myelitis, Transverse, Neuromyelitis Optica, Multiple Sclerosis, Relapsing-Remitting

NCT05245344 2022-02-17

Effects of Ozanimod on Immune-mediated Mechanisms of Neurodegeneration in Multiple Sclerosis - a Preclinical Study

Unknown

154 enrolled

Neuromyelitis Optica, Epstein-Barr Virus Infections, Multiple Sclerosis, Relapsing-Remitting

NCT00304291 2020-12-28

A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic's Disease)

Phase 4 Completed

5 enrolled

Myelitis, Transverse, Neuromyelitis Optica, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS

NCT02276963 2019-06-06

Ublituximab for Acute Neuromyelitis Optica (NMO) Relapses

Phase 1 Completed

6 enrolled 9 charts

Myelitis, Transverse, Neuromyelitis Optica, Optic Neuritis

NCT02398994 2016-07-20

STRIVE

Phase 3 Terminated

2 enrolled

Myelitis, Transverse, Neuromyelitis Optica

NCT00501748 2011-09-27

Safety and Tolerability of Rituximab in Neuromyelitis Optica

Phase 1 Completed

20 enrolled

Myelitis, Transverse, Neuromyelitis Optica

Clinical Trials

Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/ BCMA（QT-019C） in Patients With r/ r Neurological Autoimmune Diseases

Tongji NADs Cohort

The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/B Cell Maturation Antigen （CD19/BCMA） in Patients With r/r Neurological Autoimmune Diseases

Biobank For MS And Other Demyelinating Diseases

Safety and Efficacy of BAFF-R CART for Refractory Neuroimmune Diseases

NAD-AIRE

Universal CAR-T Cells in Patients with Refractory Autoimmune Diseases of the Nervous System.

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Biomarkers in Autoimmune Disease of Nervous System

SONICS

Effects of Ozanimod on Immune-mediated Mechanisms of Neurodegeneration in Multiple Sclerosis - a Preclinical Study

A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic's Disease)

Ublituximab for Acute Neuromyelitis Optica (NMO) Relapses

STRIVE

Safety and Tolerability of Rituximab in Neuromyelitis Optica