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Rasmussen subacute encephalitis, Autoimmune Diseases, Myasthenia Gravis, Neuromyelitis Optica, Lambert-Eaton Myasthenic Syndrome, Stiff-Person Syndrome, Autoimmune Diseases of the Nervous System, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating, Vasculitis, Central Nervous System, Opsoclonus-Myoclonus Syndrome

NCT07392528 2026-02-11

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/ BCMA（QT-019C） in Patients With r/ r Neurological Autoimmune Diseases

Phase EARLY_PHASE1 Not yet recruiting

15 enrolled

Multiple Sclerosis, Myasthenia Gravis, Neuromyelitis Optica

NCT06939166 2025-12-15

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/B Cell Maturation Antigen （CD19/BCMA） in Patients With r/r Neurological Autoimmune Diseases

Phase EARLY_PHASE1 Recruiting

12 enrolled

Multiple Sclerosis, Myasthenia Gravis, Neuromyelitis Optica, Autoimmune Diseases of the Nervous System, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT07022197 2025-06-15

Safety and Efficacy of BAFF-R CART for Refractory Neuroimmune Diseases

Phase 1/2 Recruiting

27 enrolled

Myasthenia Gravis, Myositis, Neuromyelitis Optica, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT06485232 2025-01-01

Universal CAR-T Cells in Patients with Refractory Autoimmune Diseases of the Nervous System.

Phase EARLY_PHASE1 Not yet recruiting

25 enrolled

Multiple Sclerosis, Myasthenia Gravis, Neuromyelitis Optica, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT04561557 2024-10-30

CARTinNS

Phase EARLY_PHASE1 Recruiting

36 enrolled

Plasma cell

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease, Autoimmune Diseases, Multiple Sclerosis, Myasthenia Gravis, Myositis, Neuromyelitis Optica, POEMS Syndrome, Autoimmune Diseases of the Nervous System, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT00304291 2020-12-28

A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic's Disease)

Phase 4 Completed

5 enrolled

Myelitis, Transverse, Neuromyelitis Optica, Autoimmune Diseases of the Nervous System, Demyelinating Autoimmune Diseases, CNS

NCT02276963 2019-06-06

Ublituximab for Acute Neuromyelitis Optica (NMO) Relapses

Phase 1 Completed

6 enrolled 9 charts

Myelitis, Transverse, Neuromyelitis Optica, Optic Neuritis

NCT02398994 2016-07-20

STRIVE

Phase 3 Terminated

2 enrolled

Myelitis, Transverse, Neuromyelitis Optica

NCT00501748 2011-09-27

Safety and Tolerability of Rituximab in Neuromyelitis Optica