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NCT06680037 2026-02-27

A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

Phase 1 Recruiting

32 enrolled

Multiple Sclerosis, Myasthenia Gravis, Neuromyelitis Optica, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT06939166 2025-12-15

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/B Cell Maturation Antigen （CD19/BCMA） in Patients With r/r Neurological Autoimmune Diseases

Phase EARLY_PHASE1 Recruiting

12 enrolled

Multiple Sclerosis, Myasthenia Gravis, Neuromyelitis Optica, Autoimmune Diseases of the Nervous System, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT07022197 2025-06-15

Safety and Efficacy of BAFF-R CART for Refractory Neuroimmune Diseases

Phase 1/2 Recruiting

27 enrolled

Myasthenia Gravis, Myositis, Neuromyelitis Optica, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT06941584 2025-04-24

NAD-AIRE

Recruiting

40 enrolled

Myasthenia Gravis, Neuromyelitis Optica, Polyendocrinopathies, Autoimmune, Autoimmune Diseases of the Nervous System, Isaacs Syndrome

NCT05017142 2024-12-16

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Recruiting

500 enrolled

CNS

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease, Encephalitis, Encephalomyelitis, Acute Disseminated, Multiple Sclerosis, Myelitis, Transverse, Neuromyelitis Optica, Optic Neuritis, Autoimmune Diseases of the Nervous System, Vasculitis, Central Nervous System, Lupus Vasculitis, Central Nervous System, Anti-N-Methyl-D-Aspartate Receptor Encephalitis

NCT06502015 2024-11-20

Biomarkers in Autoimmune Disease of Nervous System

Recruiting

50,000 enrolled

Autoimmune Diseases, Encephalomyelitis, Acute Disseminated, Multiple Sclerosis, Myasthenia Gravis, Myositis, Neuromyelitis Optica, Stiff-Person Syndrome, Autoimmune Diseases of the Nervous System, Guillain-Barre Syndrome, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating