Clinical Trials Browser

Phase 3 × Interventional × Neurotoxicity Syndromes × Clear all

NCT07320950 2026-01-06

Neuroprotective Effect of Neurotropin on Chronic OXA-induced Neurotoxicity in Stage II and Stage III CRC Patients

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00978458 2025-09-08

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Phase 3 Active not recruiting

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT06950190 2025-08-12

(ECCPC)

Phase 3 Enrolling by invitation

Chemotherapy-Related Cognitive Impairment, Neurotoxicity Syndromes, Cognitive Dysfunction

NCT00660842 2023-03-24

MITO-7

Phase 3 Unknown

Ovarian Neoplasms, Neurotoxicity Syndromes

NCT01372774 2022-09-16

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Phase 3 Completed

194 enrolled 11 charts

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries, Neurotoxicity Syndromes

NCT00039780 2022-07-13

Evaluation of BNP7787 for the Prevention of Neurotoxicity in Metastatic Breast Cancer Patients Receiving Weekly Paclitaxel

Phase 3 Completed

Breast Diseases, Breast Neoplasms, Neoplasm Metastasis, Neoplasms, Paresthesia, Neurotoxicity Syndromes

NCT00369564 2021-08-11

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

Phase 3 Completed

250 enrolled 10 charts

GenitourinaryLymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Kidney Neoplasms, Leukemia, Lymphoma, Wilms Tumor, Peripheral Nervous System Diseases, Sarcoma, Lymphoma, Large B-Cell, Diffuse, Neurotoxicity Syndromes, Dendritic Cell Sarcoma, Interdigitating

NCT00807768 2019-03-20

Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer

Phase 3 Unknown

601 enrolled 13 charts

Fatigue, Obesity, Neurotoxicity Syndromes

NCT00068445 2018-05-04

Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Phase 3 Completed

131 enrolled 14 charts

Pain, Neurotoxicity Syndromes

NCT01279681 2017-12-08

Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer

Phase 3 Terminated

32 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00516503 2017-08-24

Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Phase 3 Completed

208 enrolled 12 charts

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Leukemia, Lymphoma, Lymphoproliferative Disorders, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Pain, Neurotoxicity Syndromes, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases

NCT00566852 2017-08-21

Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors

Phase 3 Completed

554 enrolled 12 charts

Brain Neoplasms, Neoplasm Metastasis, Neurotoxicity Syndromes

NCT00775645 2017-08-14

S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing Chemo

Phase 3 Completed

437 enrolled 14 charts

Breast Neoplasms, Fatigue, Neurotoxicity Syndromes

NCT02311907 2017-02-23

Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer

Phase 3 Completed

195 enrolled 12 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms, Pain, Neurotoxicity Syndromes

NCT00316914 2016-08-11

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery

Phase 3 Completed

104 enrolled 15 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00046891 2016-07-06

EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer

Phase 3 Completed

226 enrolled 12 charts

Breast Neoplasms, Neurotoxicity Syndromes

NCT00363129 2016-07-06

Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for Cancer

Phase 3 Completed

207 enrolled 13 charts

Neurotoxicity Syndromes

NCT00027963 2016-07-04

Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy

Phase 3 Completed

Pain, Neurotoxicity Syndromes

NCT01882621 2016-06-01

Monosialoganglioside(GM1) Preventing Neurotoxicity Induced by Cisplatin Contained Chemotherapy in NSCLC Patients

Phase 3 Unknown

Carcinoma, Non-Small-Cell Lung, Neurotoxicity Syndromes

NCT00305188 2016-05-04

Evaluation of the Efficacy of Xaliproden (SR57746A) in Preventing the Neurotoxicity of Oxaliplatin / 5FU/LV Chemotherapy.

Phase 3 Completed

Gastrointestinal

Neoplasm Metastasis, Paresthesia, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00471445 2015-11-09

Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Patients

Phase 3 Completed

462 enrolled 14 charts

Pain, Peripheral Nervous System Diseases, Neurotoxicity Syndromes

NCT02024438 2015-09-28

Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in Advanced Gastric Cancer

Phase 3 Unknown

Gastrointestinal

Stomach Neoplasms, Neurotoxicity Syndromes

NCT01492920 2014-12-31

Acetyl-L-Carnitine Hydrochloride in Preventing Peripheral Neuropathy in Patients With Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer Undergoing Chemotherapy

Phase 3 Withdrawn

Brenner Tumor, Fallopian Tube Neoplasms, Fatigue, Ovarian Neoplasms, Pain, Neurotoxicity Syndromes

NCT00112996 2014-04-08

Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer

Phase 3 Completed

Neurotoxicity Syndromes

NCT00301080 2013-12-02

D-cycloserine in the Management of Chemotherapy-Induced Peripheral Neuropathic Pain

Phase 3 Terminated

7 enrolled 3 charts

Breast Neoplasms, Pain, Neurotoxicity Syndromes

NCT00058071 2013-07-09

Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer

Phase 3 Completed

Hydatidiform Mole, Peripheral Nervous System Diseases, Neurotoxicity Syndromes, Gestational Trophoblastic Disease

NCT00991744 2012-10-10

Liposomal Cytarabine for Central Nervous System (CNS)-Treatment in High-risk Acute Lymphoblastic Leukemia (ALL)

Phase 3 Suspended

LymphoidOther hematologic neoplasm

Leukemia, Neurotoxicity Syndromes, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00272051 2006-09-13

XENOX - Evaluation of the Efficacy of Xaliproden in Reducing the Neurotoxicity of the Oxaliplatin + 5-FU/LV Chemotherapy

Phase 3 Completed

Gastrointestinal

Neoplasm Metastasis, Paresthesia, Colorectal Neoplasms, Neurotoxicity Syndromes