Clinical Trials Browser

Phase 1 × INDUSTRY × Oligodendroglioma × Clear all

Astrocytoma, Oligodendroglioma

NCT04541082 2025-12-18

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Typical Teratoid Rhabdoid Tumor, Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma

NCT02381886 2025-11-10

A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

Phase 1 Active not recruiting

166 enrolled

CNSGastrointestinalMyeloidOther hematologic neoplasm

Astrocytoma, Glioblastoma, Glioma, Leukemia, Myelodysplastic Syndromes, Oligodendroglioma, Leukemia, Myeloid, Acute, Cholangiocarcinoma

NCT05561374 2024-11-29

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma

Phase 1 Active not recruiting

16 enrolled

CNS

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT03043391 2024-04-08

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

Phase 1 Completed

8 enrolled 9 charts

CNSSarcoma

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Oligodendroglioma, Gliosarcoma

NCT02871843 2022-05-16

G-FORCE-1

Phase 1 Completed

19 enrolled

CNS

Glioblastoma, Oligodendroglioma

NCT04327011 2020-03-30

A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511

Phase 1 Terminated

65 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT02764151 2020-01-27

First in Patient Study for PF-06840003 in Malignant Gliomas

Phase 1 Terminated

17 enrolled 35 charts

CNS

Astrocytoma, Glioma, Oligodendroglioma

NCT01156584 2018-05-21

A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma

Phase 1 Completed

54 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT01470794 2018-05-21

Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor

Phase 1 Completed

58 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT01985256 2018-05-21

Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor

Phase 1 Completed

17 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT00539344 2014-07-31

A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Malignant Glioma

Phase 1 Completed

63 enrolled

CNS

Astrocytoma, Glioblastoma, Oligodendroglioma, Recurrence

NCT00006368 2013-05-01

Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer

Phase 1 Completed

60 enrolled

BreastCNSDermatologicEndocrineLymphoidOther hematologic neoplasmSarcomaThoracic

Astrocytoma, Brain Neoplasms, Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Craniopharyngioma, Vipoma, Ependymoma, Glioblastoma, Glucagonoma, Hodgkin Disease, Insulinoma, Adenoma, Islet Cell, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Medulloblastoma, Melanoma, Meningioma, Neoplasms, Oligodendroglioma, Pinealoma, Pituitary Neoplasms, Somatostatinoma, Gastrinoma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Carcinoma, Islet Cell, Glioma, Subependymal, Gliosarcoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Growth Hormone-Secreting Pituitary Adenoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Small Cell Lung Carcinoma

NCT00004212 2012-05-16

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Phase 1 Completed

CNSLymphoidSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Lymphoma, Medulloblastoma, Oligodendroglioma, Recurrence, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Dendritic Cell Sarcoma, Interdigitating

NCT00591058 2009-07-17

Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma

Phase 1 Unknown

36 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT00080054 2009-04-03

A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas

Phase 1 Completed

24 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

Clinical Trials

Study of Vorasidenib and Pembrolizumab Combination in Recurrent or Progressive IDH-1 Mutant Glioma

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

G-FORCE-1

A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511

First in Patient Study for PF-06840003 in Malignant Gliomas

A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma

Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor

Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor

A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Malignant Glioma

Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma

A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas