Clinical Trials

Oligodendroglioma

NCT04702581 2026-01-29

POLO

Phase 3 Recruiting

280 enrolled

Phase 3 Active not recruiting

Oligodendroglioma

NCT00887146 2026-01-22

Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

305 enrolled

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT04623931 2026-01-14

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Phase 2 Recruiting

40 enrolled

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT05267106 2025-12-30

FIGHT-209

Phase 2 Terminated

83 enrolled 18 charts

Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT04541082 2025-12-18

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Phase 1 Recruiting

102 enrolled

Typical Teratoid Rhabdoid Tumor, Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma

NCT07031765 2025-12-18

Peds CHAMP1ON

12 enrolled

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma

NCT05956821 2025-12-08

Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

Phase 1/2 Recruiting

20 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Oligodendroglioma

NCT06930846 2025-11-21

HOBSCOTCH-CA

125 enrolled

Caregiver Burden, Brain Neoplasms, Memory Disorders, Meningioma, Oligodendroglioma, Cognitive Dysfunction

NCT02192359 2025-11-14

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

18 enrolled 16 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02381886 2025-11-10

A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

CNSGastrointestinalMyeloidOther hematologic neoplasm

166 enrolled

Astrocytoma, Glioblastoma, Glioma, Leukemia, Myelodysplastic Syndromes, Oligodendroglioma, Leukemia, Myeloid, Acute, Cholangiocarcinoma

NCT06439420 2025-10-01

CBT-I in PBT

Phase 2 Completed

70 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Sleep Initiation and Maintenance Disorders, Lymphoma, Meningioma, Oligodendroglioma

NCT06989086 2025-09-09

FearLess in NeuroOncology

112 enrolled

Phase 3 Active not recruiting

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma

NCT00978458 2025-09-08

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

540 enrolled

Phase EARLY_PHASE1 Completed

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT01165632 2025-09-02

Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma

24 enrolled

Phase EARLY_PHASE1 Recruiting

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Glioma, Subependymal, Gliosarcoma

NCT04135807 2025-07-23

Implantable Microdevice In Primary Brain Tumors

12 enrolled

Phase 2 Active not recruiting

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT03180502 2025-07-11

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

120 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT06108206 2025-07-03

Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma

20 enrolled

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT05513859 2025-06-03

Investigational Imaging Technique During Brain Surgery

Phase NA Suspended

24 enrolled

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT05297864 2025-05-23

OU-SCC-PI-4G

Phase 2 Terminated

15 enrolled 13 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT05698524 2025-05-20

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

Phase 1 Recruiting

24 enrolled

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02186509 2025-04-30

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

17 enrolled 11 charts

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT05737212 2025-02-21

Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas

Phase 1/2 Terminated

7 enrolled

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT06161974 2025-02-21

Study of Olutasidenib and Temozolomide in HGG

Phase 2 Recruiting

60 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Spinal Cord Neoplasms

NCT05190172 2025-02-12

PRO-GLIO

225 enrolled

Astrocytoma, Oligodendroglioma

NCT05561374 2024-11-29

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma

16 enrolled

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT02530320 2024-11-22

Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Patients With Oligodendroglioma or Recurrent Oligoastrocytoma Anaplastic With the Activity of the Protein RB Preserved

Phase 2 Completed

34 enrolled 13 charts

Astrocytoma, Oligodendroglioma

NCT02549833 2024-11-22

Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma

28 enrolled

Phase 2 Active not recruiting

Astrocytoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT03969706 2024-11-18

Abemaciclib in Patients with Oligodendroglioma

10 enrolled

Oligodendroglioma

NCT02101905 2024-11-06

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

29 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02372409 2024-11-01

Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

Phase 2 Terminated

6 enrolled 10 charts

Phase EARLY_PHASE1 Terminated

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Optic Nerve Glioma

NCT03796273 2024-09-19

Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases

15 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT00003375 2024-07-09

Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma

Phase 2/3 Completed

370 enrolled

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00114140 2024-07-08

Temozolomide and Radiation Therapy in Treating Patients With Gliomas

Phase 2 Completed

136 enrolled 9 charts

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT02924038 2024-06-14

A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)

Phase 1 Terminated

14 enrolled 10 charts

Astrocytoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

68 enrolled

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT03043391 2024-04-08

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

8 enrolled 9 charts