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Osteosarcoma × ceralasertib × Clear all

Phase

Status

Active not recruiting 1

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Carcinoma, Non-Small-Cell Lung 7 Triple Negative Breast Neoplasms 4 Neoplasms 4 Lung Neoplasms 4 Breast Neoplasms 3 Ovarian Neoplasms 2 Melanoma 2 Endometrial Neoplasms 2 Carcinosarcoma 2 Bile Duct Neoplasms 2 Advanced Solid Tumours 2 Uterine Cervical Neoplasms 1 Thoracic Neoplasms 1 Stomach Neoplasms 1 Squamous Cell Carcinoma of Head and Neck 1 Solid Tumour Refractory to Conventional Treatment 1 Small Cell Lung Carcinoma 1 Salivary Gland Neoplasms 1 SCLC 1 Respiratory Tract Neoplasms 1 Respiratory Tract Diseases 1 Prostatic Neoplasms 1 Platinum Refractory Extensive-Stage Small Cell Lung Carcinoma 1 Osteosarcoma 1 Non Small Cell Lung Cancer NSCLC 1 Neoplasms by Site 1 Neoplasm Metastasis 1 Myelodysplastic Syndromes 1 Lymphoma, Non-Hodgkin 1 Lymphoma, Large B-Cell, Diffuse 1

Interventions

Ifosfamide 27 Methotrexate 25 Doxorubicin 22 Cyclophosphamide 20 Cisplatin 19 Filgrastim 15 Etoposide 15 Gemcitabine 14 Leucovorin 12 Magnetic Resonance Spectroscopy 10 Temozolomide 9 Specimen Handling 9 Granulocyte Colony-Stimulating Factor 8 fludarabine 7 Zoledronic Acid 7 X-Rays 7 Sirolimus 7 Nivolumab 7 Neoadjuvant Therapy 7 Irinotecan 7 Drug Therapy 7 Docetaxel 7 Carboplatin 7 Biopsy 7 mifamurtide 6 apatinib 6 Phantoms, Imaging 6 Mesna 6 cabozantinib 5 Vincristine 5

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT04417062 2026-02-25

Olaparib With Ceralasertib in Recurrent Osteosarcoma

Dana-Farber Cancer Institute

Phase 2 Active not recruiting

Osteosarcoma

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