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Pancreatic Neoplasms × adavosertib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 1

Conditions

Ovarian Neoplasms 5 Small Cell Lung Carcinoma 4 Advanced Solid Tumours 4 Neoplasms 3 Leukemia, Myeloid, Acute 3 Glioblastoma 3 Fallopian Tube Neoplasms 3 Uterine Cervical Neoplasms 2 Triple Negative Breast Neoplasms 2 Squamous Cell Carcinoma of Head and Neck 2 Neoplasm Metastasis 2 Lung Neoplasms 2 Advanced Malignant Solid Neoplasm 2 Vaginal Neoplasms 1 Uterine Neoplasms 1 Triple-negative Metastatic Breast Cancer 1 Stomach Neoplasms 1 Solid Tumors 1 Rhabdomyosarcoma 1 Prostatic Neoplasms 1 Platinum Refractory Extensive-Stage Small Cell Lung Carcinoma 1 Pinealoma 1 Pancreatic Neoplasms 1 Ovarian, Fallopian Tube, Peritoneal Cancer, P53 Mutation 1 Neuroectodermal Tumors, Primitive 1 Neuroblastoma 1 Myelodysplastic-Myeloproliferative Diseases 1 Myelodysplastic Syndromes 1 Muscle Invasive Bladder Cancer 1 Multiple Myeloma 1

Interventions

Gemcitabine 616 130-nm albumin-bound paclitaxel 174 Fluorouracil 170 Oxaliplatin 155 Albumin-Bound Paclitaxel 138 Leucovorin 121 Capecitabine 120 Irinotecan 104 Radiotherapy 89 Taxes 77 pembrolizumab 73 Cisplatin 70 Erlotinib Hydrochloride 65 Radiosurgery 61 Bevacizumab 50 Nivolumab 49 Cyclophosphamide 46 Magnetic Resonance Spectroscopy 45 Drug Therapy 44 folfirinox 39 Specimen Handling 37 Docetaxel 37 Cetuximab 36 irinotecan sucrosofate 35 S 1 (combination) 34 Biopsy 33 Blood Specimen Collection 31 Pancreaticoduodenectomy 29 Paclitaxel 29 Radiation 26

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT05212025 2022-06-14

Adavosertib and Gemcitabine in Advanced Pancreatic

Dana-Farber Cancer Institute

Phase 2 Withdrawn

Gastrointestinal

Pancreatic Neoplasms

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