Clinical Trials Browser

Interventional × Pancreatic Neoplasms × irinotecan sucrosofate × Clear all

NCT04233866 2026-03-02

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

Phase 2 Active not recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT06998940 2026-02-20

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

Phase 3 Recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT06958328 2026-02-02

LAP100

Phase 3 Recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT04390399 2025-12-15

Combination Immunotherapy Plus Standard-of-Care Chemotherapy Versus Standard-of-Care Chemotherapy for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer

Phase 2 Active not recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT06625320 2025-12-12

RASolute 302

Phase 3 Active not recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT03693677 2025-07-01

FUNGEMAX

Phase 2 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT05277766 2025-07-01

PIPAC-NAL-IRI

Phase 1 Recruiting

GastrointestinalGynecologic

Appendiceal Neoplasms, Bile Duct Neoplasms, Pancreatic Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT03468335 2025-04-17

PREDICT

Phase 3 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT06766019 2025-01-09

Adebrelimab Combined With Irinotecan Liposomal (II), Oxaliplatin, and 5-FU/LV Conversion Therapy for Locally Advanced Pancreatic Cancer

Phase 2 Active not recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT03368963 2025-01-07

TAS102 in Combination With NAL-IRI in Advanced GI Cancers

Phase 1/2 Active not recruiting

Gastrointestinal

Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05859750 2024-12-16

A Study of AK104 With Chemotherapy as First-line Treatment in Patients With Advanced Pancreatic Cancer

Phase 2 Recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT06700603 2024-11-22

Second-line Irinotecan Liposome Combination Regimen for Irinotecan-treated Pancreatic Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT02697058 2024-07-25

Phase II of BAX2398/5-FU/Calcium Levofolinate in Pancreatic Cancer

Phase 2 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT06513455 2024-07-22

Irinotecan Liposome，Albumin Paclitaxel and Gemcitabine First-line Treatment for Pancreatic Cancer

Phase 1/2 Not yet recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT04371224 2024-04-19

NaliCap

Phase 2 Recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT06370754 2024-04-17

FD-IMPACT

Phase 1/2 Not yet recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT06361316 2024-04-11

Irinotecan Liposome Combined With Oxaliplatin and Tegafur as Adjuvant Therapy for Pancreatic Cancer

Phase NA Recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT06259058 2024-03-15

Stereotactic Body Radiation Therapy Followed by NALIRIFOX vs NALIRIFOX for Borderline Resectable Pancreatic Cancer

Phase 1/2 Not yet recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT06210360 2024-01-18

Perioperative Treatment in High-risk Resectable Pancreatic Cancer With NALIRIFOX

Phase 2 Not yet recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT02231723 2023-11-18

A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Pancreatic Cancer

Phase 1 Completed

Gastrointestinal

Pancreatic cancer, adult, Digestive System Neoplasms, Endocrine Gland Neoplasms, Adenoma, Islet Cell, Pancreatic Diseases, Pancreatic Neoplasms, Carcinoma, Islet Cell, Carcinoma, Pancreatic Ductal

NCT05363007 2023-10-16

SINAI

Phase 2 Unknown

Gastrointestinal

Pancreatic Neoplasms

NCT05251038 2023-05-11

Study of Sotorasib Combined With Chemotherapy for Second Line Treatment of Pancreas Cancer

Phase 1/2 Withdrawn

Gastrointestinal

Pancreatic Neoplasms

NCT01926197 2022-10-28

Phase 3 Study of FOLFIRINOX (mFFX) +/- SBRT in Locally Advanced Pancreatic Cancer

Phase 3 Completed

27 enrolled 15 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02551991 2022-10-10

Study of Nanoliposomal Irinotecan (Nal-IRI)-Containing Regimens Versus Nab-paclitaxel Plus Gemcitabine in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma

Phase 2 Completed

56 enrolled 19 charts

Gastrointestinal

Pancreatic Neoplasms

NCT03487016 2022-09-08

FOOTPATH

Phase 2 Unknown

Gastrointestinal

Neoplasm Metastasis, Pancreatic Neoplasms

NCT03703063 2021-01-27

Alternative Neoadjuvant Chemotherapy in Resectable and Borderline Resectable Pancreatic Cancer

Phase 1 Unknown

Gastrointestinal

Pancreatic Neoplasms

NCT03986294 2021-01-15

NAPAN

Phase 2 Unknown

Gastrointestinal

Pancreatic Neoplasms

NCT03207724 2020-12-30

OnFX

Phase 1 Completed

Gastrointestinal

Adenocarcinoma, Cachexia, Disease, Pancreatic Neoplasms, Weight Loss

NCT01770353 2019-11-27

MM-398 (Nanoliposomal Irinotecan, Nal-IRI) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment

Phase 1 Completed

45 enrolled 33 charts

BreastGastrointestinalGynecologicHead & Neck

Head and Neck Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT01494506 2016-06-17

NAPOLI-1

Phase 3 Completed

417 enrolled 20 charts

Gastrointestinal

Pancreatic Neoplasms