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Phase 3 × Pathologic Complete Response × Chemoradiotherapy × Clear all

Phase

Phase NA 1 Phase 3 1 Phase 2 1

Status

Not yet recruiting 1

Sponsor Class

Study Type

Interventional 1

Sponsor

Conditions

Rectal Neoplasms 11 Esophageal Neoplasms 3 Carcinoma, Non-Small-Cell Lung 3 Uterine Cervical Neoplasms 2 Stomach Neoplasms 2 Squamous Cell Carcinoma of Head and Neck 2 Neoplasms 2 Nasopharyngeal Carcinoma 2 Adenocarcinoma 2 Pathologic Complete Response 1 Overall Survival Comparison Between the 2 Arms 1 Oropharyngeal Neoplasms 1 Nasopharyngeal Neoplasms 1 Mouth Neoplasms 1 Margins of Excision 1 Locally Advanced Malignant Neoplasm 1 Laryngeal Neoplasms 1 Laryngeal Diseases 1 Head and Neck Neoplasms 1 HPV-Related Squamous Cell Carcinoma 1 Gallbladder Neoplasms 1 Esophageal Squamous Cell Carcinoma 1 Colorectal Neoplasms 1 Cholangiocarcinoma 1 Carcinoma, Adenosquamous 1 Anus Neoplasms 1 Anal Canal Carcinoma 1

Interventions

Cyclophosphamide 3 Epirubicin 2 Docetaxel 2 Carboplatin 2 Capecitabine 2 Azacitidine 2 venetoclax 1 tegafur-gimeracil-oteracil 1 taxane 1 sargramostim 1 ruxolitinib 1 rucaparib 1 pirarubicin 1 pertuzumab 1 pembrolizumab 1 olaparib 1 cc-486 1 Trastuzumab 1 Thalidomide 1 Radiotherapy 1 Radiation 1 Platinum 1 Paclitaxel 1 Oxaliplatin 1 Observation 1 Nivolumab 1 Monatide (IMS 3015) 1 Methotrexate 1 Magnetic Resonance Imaging 1 Leucovorin 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT07472868 2026-03-16

MEND-IT II

Catharina Ziekenhuis Eindhoven

Phase 3 Not yet recruiting

Pathologic Complete Response

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