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Clinical Trials

1 trials

Recent Start date Enrollment

OTHER × Phase IB × defactinib × Clear all

Phase

Status

Not yet recruiting 1

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Pancreatic Neoplasms 6 Glioblastoma 2 Uveal Melanoma 1 Uterine Cervical Neoplasms 1 Thyroid Neoplasms 1 Stomach Neoplasms 1 Phase IB 1 Ovarian Neoplasms 1 Neoplasms 1 Mesothelioma, Malignant 1 Mesothelioma 1 Melanoma 1 Lung Neoplasms 1 Low-Grade Serous Ovarian Cancer 1 Carcinoma, Non-Small-Cell Lung 1 Carcinoma, Endometrioid 1 Brain Neoplasms 1 Advanced Colorectal Cancer 1 Adenocarcinoma of Lung 1

Interventions

defactinib 1 Everolimus 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT07318324 2026-01-06

Phase Ib Study of Avutometinib, Defactinib, and Everolimus in RAS Pathway Mutant Endometrial Cancer

M.D. Anderson Cancer Center

Phase 1 Not yet recruiting

Phase IB

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