Clinical Trials Browser

Mesothelioma, Malignant, Pleural Effusion, Malignant

NCT07332858 2026-01-14

First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion

Phase 1/2 Not yet recruiting

105 enrolled

MyeloidThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Carcinoma, Non-Small-Cell Lung, Pleural Effusion, Malignant

NCT07167992 2026-01-06

Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis

Phase NA Not yet recruiting

160 enrolled

Thoracic

Pneumothorax, Pleural Effusion, Malignant

NCT00761618 2025-10-28

Intrapleural Catheter Daily Versus Three Times a Week Drainage

Phase 2 Active not recruiting

257 enrolled

Thoracic

Pleural Effusion, Pleural Effusion, Malignant

NCT05620329 2025-10-16

UNC Pleural Fluid Registry

Recruiting

9,999 enrolled

BreastThoracic

Breast Neoplasms, Empyema, Infections, Lung Neoplasms, Neoplasms, Pleural Effusion, Malignant

NCT03235999 2025-10-03

The Experiences of Patients Living With Malignant Pleural Effusions

Completed

10 enrolled

Thoracic

Pleural Effusion, Malignant

NCT07147270 2025-08-29

Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound

Phase NA Recruiting

30 enrolled

Thoracic

Pleural Effusion, Malignant

NCT02122185 2025-06-08

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2 Active not recruiting

110 enrolled

GynecologicThoracic

Carcinoma, Ovarian Epithelial, Brenner Tumor, Fallopian Tube Neoplasms, Pleural Effusion, Malignant

NCT06657638 2025-05-29

Cytological Examination of Malignant Pleural Effusion in Breast Cancer

Completed

50 enrolled

BreastThoracic

Breast Neoplasms, Pleural Effusion, Malignant

NCT06016179 2025-05-22

RIOT2

Phase 1 Recruiting

12 enrolled

Thoracic

Pleural Effusion, Malignant

NCT06964321 2025-05-09

Effectiveness of Intercostal Tube Drainage Vs Pigtail Catheter Drainage Vs Ultrasound-Guided Aspiration in Management of Massive Malignant Pleural Effusion

Phase NA Not yet recruiting

66 enrolled

Thoracic

Pleural Effusion, Malignant

NCT06959719 2025-05-07

ARMSTRONG

Phase NA Recruiting

41 enrolled

MyeloidThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Pleural Effusion, Pleural Effusion, Malignant

NCT06946498 2025-04-27

FLAT

Phase NA Recruiting

100 enrolled

Other solid neoplasmThoracic

Mesothelioma, Malignant, Lung Neoplasms, Mesothelioma, Pleural Effusion, Pleural Effusion, Malignant

NCT04669223 2025-03-28

Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion

Phase NA Terminated

52 enrolled

Thoracic

Lung Neoplasms, Pleural Effusion, Malignant

Clinical Trials

RIOT 4B

First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion

Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis

Intrapleural Catheter Daily Versus Three Times a Week Drainage

UNC Pleural Fluid Registry

The Experiences of Patients Living With Malignant Pleural Effusions

Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Cytological Examination of Malignant Pleural Effusion in Breast Cancer

RIOT2

Effectiveness of Intercostal Tube Drainage Vs Pigtail Catheter Drainage Vs Ultrasound-Guided Aspiration in Management of Massive Malignant Pleural Effusion

ARMSTRONG

FLAT

Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion