Clinical Trials Browser

Mesothelioma, Malignant, Pleural Effusion, Malignant

NCT07332858 2026-01-14

First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion

Phase 1/2 Not yet recruiting

105 enrolled

MyeloidThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Carcinoma, Non-Small-Cell Lung, Pleural Effusion, Malignant

NCT07167992 2026-01-06

Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis

Phase NA Not yet recruiting

160 enrolled

Thoracic

Pneumothorax, Pleural Effusion, Malignant

NCT04914598 2026-01-02

A Phase Ⅲ Clinical Study of Combined Cisplatin Versus Placebo Combined With Intracavitary Cisplatin Injection in the Treatment of Malignant Pleural Effusions

Phase 3 Active not recruiting

290 enrolled

Thoracic

Pleural Effusion, Malignant

NCT02649894 2025-12-11

SWIFT

Phase NA Completed

119 enrolled 16 charts

Thoracic

Pleural Effusion, Malignant

NCT00761618 2025-10-28

Intrapleural Catheter Daily Versus Three Times a Week Drainage

Phase 2 Active not recruiting

257 enrolled

Thoracic

Pleural Effusion, Pleural Effusion, Malignant

NCT07147270 2025-08-29

Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound

Phase NA Recruiting

30 enrolled

Thoracic

Pleural Effusion, Malignant

NCT06210685 2025-08-11

The ACES Study for Aseptic Pleural Effusion

Phase NA Active not recruiting

25 enrolled

Thoracic

Pleural Effusion, Pleural Effusion, Malignant

NCT05543330 2025-07-20

A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC

Phase 1/2 Recruiting

96 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Pleural Effusion, Malignant

NCT02122185 2025-06-08

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2 Active not recruiting

110 enrolled

GynecologicThoracic

Carcinoma, Ovarian Epithelial, Brenner Tumor, Fallopian Tube Neoplasms, Pleural Effusion, Malignant

NCT06016179 2025-05-22

RIOT2

Phase 1 Recruiting

12 enrolled

Thoracic

Pleural Effusion, Malignant

NCT06964321 2025-05-09

Effectiveness of Intercostal Tube Drainage Vs Pigtail Catheter Drainage Vs Ultrasound-Guided Aspiration in Management of Massive Malignant Pleural Effusion

Phase NA Not yet recruiting

66 enrolled

Thoracic

Pleural Effusion, Malignant

NCT06959719 2025-05-07

ARMSTRONG

Phase NA Recruiting

41 enrolled

MyeloidThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Pleural Effusion, Pleural Effusion, Malignant

NCT06946498 2025-04-27

FLAT

Phase NA Recruiting

100 enrolled

Other solid neoplasmThoracic

Mesothelioma, Malignant, Lung Neoplasms, Mesothelioma, Pleural Effusion, Pleural Effusion, Malignant

NCT06740019 2025-04-04

A Phase Ib Study of JMKX000197 Injection in the Treatment of Malignant Pleural Effusion

Phase 1 Recruiting

30 enrolled

MyeloidThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Pleural Effusion, Malignant

NCT04669223 2025-03-28

Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion

Phase NA Terminated

52 enrolled

Thoracic

Lung Neoplasms, Pleural Effusion, Malignant

Clinical Trials

RIOT 4B

First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion

Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis

A Phase Ⅲ Clinical Study of Combined Cisplatin Versus Placebo Combined With Intracavitary Cisplatin Injection in the Treatment of Malignant Pleural Effusions

SWIFT

Intrapleural Catheter Daily Versus Three Times a Week Drainage

Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound

The ACES Study for Aseptic Pleural Effusion

A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

RIOT2

Effectiveness of Intercostal Tube Drainage Vs Pigtail Catheter Drainage Vs Ultrasound-Guided Aspiration in Management of Massive Malignant Pleural Effusion

ARMSTRONG

FLAT

A Phase Ib Study of JMKX000197 Injection in the Treatment of Malignant Pleural Effusion

Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion