Clinical Trials Browser

Mesothelioma, Malignant, Pulmonary Atelectasis, Hemothorax, Lung Diseases, Pericardial Effusion, Pleural Diseases, Pleural Neoplasms, Pneumothorax, Pleural Effusion, Malignant, Empyema, Pleural, Respiratory Aspiration

NCT03597009 2021-04-20

A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion

Phase 1/2 Terminated

1 enrolled 12 charts

Thoracic

Lung Neoplasms, Neoplasm Metastasis, Pleural Effusion, Malignant

NCT01302808 2021-01-20

Romidepsin and Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Phase 1 Completed

17 enrolled 12 charts

Thoracic

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Pleural Effusion, Malignant

NCT01999985 2020-11-27

Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC)

Phase 1 Completed

25 enrolled 10 charts

Thoracic

Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Pleural Diseases, Pleural Effusion, Pleural Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Pleural Effusion, Malignant

NCT00601848 2020-11-24

Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the Pleura

Phase 2 Terminated

9 enrolled 5 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Pleural Effusion, Malignant

NCT04233359 2020-09-28

A Randomised Study Evaluating Diagnostics of Pleural Effusion Among Patients Suspect of Cancer.

Phase NA Terminated

4 enrolled

Thoracic

Pleural Effusion, Pleural Effusion, Malignant

NCT01411202 2020-09-25

OPUS

Phase 2 Unknown

40 enrolled

Thoracic

Pleural Effusion, Malignant

NCT03403855 2020-09-25

Rocket® Pleural Catheters: QOL, Feasibility and Satisfaction in Recurrent MPE Patients

Phase NA Unknown

100 enrolled

Thoracic

Pleural Effusion, Malignant

NCT04236037 2020-09-25

Ultrasound-guided Biopsy of the Pleura as a Supplement to Extraction of Fluid in Patients With One-sided Fluid in the Pleura

Phase NA Terminated

5 enrolled

Thoracic

Pleural Effusion, Malignant

NCT00066404 2020-05-13

Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions

Phase 1 Completed

BreastDermatologicGastrointestinalGenitourinaryGynecologicOther solid neoplasmThoracic

Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thymoma, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Pleural Effusion, Malignant, Endometrial Neoplasms, Breast Neoplasms, Male, Gestational Trophoblastic Disease, Small Cell Lung Carcinoma

NCT03325192 2020-05-08

RAPID

Phase NA Terminated

11 enrolled

Thoracic

Pleural Diseases, Pleural Effusion, Malignant

NCT02674243 2020-01-23

Efficacy of Iodopovidone Versus Talc in Palliative Malignant Pleural Effusion

Phase 3 Completed

60 enrolled

Thoracic

Pleural Effusion, Malignant

NCT04131231 2019-10-18

Safety and Effectiveness of MPCD Therapy on the Treatment of Malignant Pleural Effusion

Phase NA Unknown

248 enrolled

BreastThoracic

Breast Neoplasms, Lung Neoplasms, Pleural Effusion, Malignant

NCT02132884 2019-09-04

Genetic Sequencing-Informed Targeted Therapy in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer

Phase NA Terminated

1 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Pleural Effusion, Malignant

NCT02623959 2019-08-07

Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis

Phase 4 Terminated

3 enrolled 4 charts

Thoracic

Pleural Effusion, Malignant

NCT03973957 2019-06-04

TOPIC

Phase NA Unknown

124 enrolled

Thoracic

Pleural Diseases, Pleural Effusion, Pleural Effusion, Malignant

NCT02054052 2019-03-29

Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer

Phase 2 Completed

22 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Pericardial Effusion, Pleural Effusion, Malignant

NCT02702700 2019-03-20

PDT-lipo

Phase 1 Terminated

1 enrolled

Thoracic

Pleural Effusion, Malignant

NCT03394105 2019-03-08

Intrapleural Docetaxel Administration Using Medical Pleuroscopy in Malignant Effusion With Lung Cancer

Phase 2 Completed

4 enrolled

Thoracic

Pleural Effusion, Malignant

NCT02657460 2019-02-26

Clinical Trial of Tumor Cell-derived Microparticles Packaging Chemotherapeutic Drugs to Treat Malignant Pleural Effusion

Phase 2 Unknown

90 enrolled

Thoracic

Pleural Effusion, Malignant

Clinical Trials

RIOT 4B

First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion

Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis

Intrapleural Catheter Daily Versus Three Times a Week Drainage

Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

RIOT2

Effectiveness of Intercostal Tube Drainage Vs Pigtail Catheter Drainage Vs Ultrasound-Guided Aspiration in Management of Massive Malignant Pleural Effusion

ARMSTRONG

FLAT

Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion

Thoracoscopic Talc Pleurodesis Versus Bleomycin -Tranxemic Acid Mixture Injection in Chest Tube in Malignant Pleural Effusion

The Outcome of Inserting Intercostal Tube or Pleurodesis for Malignant Pleural Effusion

Pleural Bleomycin vs Mechanical Abrasion in Malignant Pleural Effusion

Feasibility of Ambulatory Talc. Pleurodesis

Dual-targeting HER2 and PD-L1 CAR-T for Solid Tumors

Clinical Study on Intraluminal Injection of FOLactis

OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.

IFN-γ Combined With T Cells in the Treatment of Refractory Malignant Pleural Effusion and Ascites

AMPLE-3

OPTIMUM

Efficacy and Safety Study of Medical Thoracoscope Cryotherapy Combined Standard First-line Treatment of Advanced Non-small Cell Lung Cancer and Malignant Pleural Effusion

Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion

MICRO

Intrapleural Instillation of the Nivolumab in Cancer Patients With Pleural Effusion.

A Study to Compare the Efficacy and Safety of Intrapleural Doxycycline Versus Iodopovidone for Performing Pleurodesis in Malignant Pleural Effusion

Safety and Efficacy Study of Virus Activated Killer Immune Cells (VAK) for Malignant Pleural and Peritoneal Effusion

Tunneled Pleural Catheter in Partially Entrapped Lung

Oncodrivers in Malignant Pleural Effusions Associated With Non-small Cell Lung Cancer: A Prospective Study.

A Study of Intrapleural Administration of Bevacizumab and Camrelizumab for Malignant Pleural Effusion

VATS

A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion

Romidepsin and Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC)

Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the Pleura

A Randomised Study Evaluating Diagnostics of Pleural Effusion Among Patients Suspect of Cancer.

OPUS

Rocket® Pleural Catheters: QOL, Feasibility and Satisfaction in Recurrent MPE Patients

Ultrasound-guided Biopsy of the Pleura as a Supplement to Extraction of Fluid in Patients With One-sided Fluid in the Pleura

Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions

RAPID

Efficacy of Iodopovidone Versus Talc in Palliative Malignant Pleural Effusion

Safety and Effectiveness of MPCD Therapy on the Treatment of Malignant Pleural Effusion

Genetic Sequencing-Informed Targeted Therapy in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer

Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis

TOPIC

Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer

PDT-lipo

Intrapleural Docetaxel Administration Using Medical Pleuroscopy in Malignant Effusion With Lung Cancer

Clinical Trial of Tumor Cell-derived Microparticles Packaging Chemotherapeutic Drugs to Treat Malignant Pleural Effusion