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1 trials

Recent Start date Enrollment

Primary Malignant Peripheral Nerve Sheath Tumors × mirdametinib × 90 days × Clear all

Phase

Phase EARLY_PHASE1 1

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Conditions

Vascular Malformations 1 Skin Diseases, Vascular 1 Primary Malignant Peripheral Nerve Sheath Tumors 1 Multiple Myeloma 1 Lymphatic Abnormalities 1 Lymphangioma, Cystic 1 Lymphangioma 1 Liposarcoma, Myxoid 1 Liposarcoma 1 Arteriovenous Malformations 1

Interventions

mirdametinib 1 Vorinostat 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT06693284 2026-02-03

A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]

University of Minnesota

Phase EARLY_PHASE1 Recruiting

Primary Malignant Peripheral Nerve Sheath Tumors

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