Clinical Trials

90 enrolled

Phase 1 Active not recruiting

Rectal Neoplasms, Colorectal Neoplasms

NCT06704724 2026-03-13

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

30 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT04668872 2026-03-12

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

Recruiting

80 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07467434 2026-03-12

SYNCHRONOX

Not yet recruiting

550 enrolled

Phase NA Not yet recruiting

Rectal Neoplasms

NCT07463261 2026-03-11

RELOAD

442 enrolled

Rectal Neoplasms, Anastomotic Leak

NCT06802172 2026-03-10

Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial

100 enrolled

BreastGastrointestinal

Intermittent Fasting, Breast Neoplasms, Rectal Neoplasms

NCT07460596 2026-03-10

Concentrated Complex Plant Dietary Elements for Chemotherapy-Induced Diarrhea

Phase 2 Completed

30 enrolled

Esophageal Neoplasms, Rectal Neoplasms

NCT00102011 2026-03-09

00-046

Phase 3 Completed

4,952 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06647680 2026-03-06

Neoadjuvant Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer（CONTROL-01）

35 enrolled

BreastCNSGastrointestinalGenitourinaryHead & NeckThoracic

Pathologic Complete Response, Rectal Neoplasms

NCT04075305 2026-03-05

MOMENTUM

Recruiting

8,000 enrolled

Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Genital Neoplasms, Female, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Radiation Injuries, Rectal Neoplasms

NCT05731726 2026-03-05

Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer

50 enrolled

Rectal Neoplasms

NCT06952101 2026-03-05

INTERPRETE

200 enrolled

Rectal Neoplasms

NCT05672524 2026-03-04

A Study of Tucatinib and Trastuzumab in People With Rectal Cancer

37 enrolled

Adenocarcinoma, Rectal Neoplasms

NCT07448662 2026-03-04

COLBRAIN

Active not recruiting

700 enrolled

CNSGastrointestinal

Brain Neoplasms, Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04215731 2026-03-03

FOBEAR

Phase 3 Recruiting

582 enrolled

Rectal Neoplasms

NCT05080673 2026-03-03

FORTE

9,500 enrolled

Phase 3 Active not recruiting

Colonic Neoplasms, Rectal Neoplasms

NCT04928807 2026-02-27

Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer (UNION)

231 enrolled

Phase 2 Not yet recruiting

Rectal Neoplasms

NCT07176182 2026-02-27

Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression

236 enrolled

Phase NA Not yet recruiting

Rectal Neoplasms

NCT07369531 2026-02-27

RC09-FIAS

498 enrolled

Neoplasms, Rectal Neoplasms

NCT06447662 2026-02-25

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Phase 1 Recruiting

330 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT06769061 2026-02-25

AcuCIN

75 enrolled

Phase NA Active not recruiting

Rectal Neoplasms

NCT07432542 2026-02-25

TOWER-1

516 enrolled

Intestinal Obstruction, Rectal Neoplasms, Ileus

NCT07433673 2026-02-25

GAP Cemi

20 enrolled

GastrointestinalGynecologic

Rectal Neoplasms

NCT06625515 2026-02-24

First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers

Phase 1 Terminated

17 enrolled

Colonic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms, Microsatellite Instability

NCT07429110 2026-02-24

ColoSeal™ ICD System Anastomotic Protection Pivotal Study

Phase NA Not yet recruiting

250 enrolled

Rectal Neoplasms

NCT07427901 2026-02-23

Quality Of Life In Colorectal Cancer Survivors

368 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07428239 2026-02-23

Pilot Study of Individualized Comprehensive Rehabilitation in Patients With Colorectal Cancer

Phase NA Completed

150 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT04907643 2026-02-20

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes