Clinical Trials

50 enrolled

Rectal Neoplasms

NCT06952101 2026-03-05

INTERPRETE

200 enrolled

Rectal Neoplasms

NCT05672524 2026-03-04

A Study of Tucatinib and Trastuzumab in People With Rectal Cancer

37 enrolled

Adenocarcinoma, Rectal Neoplasms

NCT04215731 2026-03-03

FOBEAR

Phase 3 Recruiting

582 enrolled

Rectal Neoplasms

NCT05080673 2026-03-03

FORTE

9,500 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT06447662 2026-02-25

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Phase 1 Recruiting

330 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT06769061 2026-02-25

AcuCIN

75 enrolled

Rectal Neoplasms

NCT07433673 2026-02-25

GAP Cemi

20 enrolled

Rectal Neoplasms

NCT07427901 2026-02-23

Quality Of Life In Colorectal Cancer Survivors

368 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04907643 2026-02-20

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

EndocrineGastrointestinalNET

360 enrolled

Cancer Pain, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Biliary Tract Neoplasms, Carcinoid Tumor, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Stomach Neoplasms, Neuroendocrine Tumors, Visceral Pain

NCT06051695 2026-02-20

EVEREST-2

Phase 1/2 Recruiting

474 enrolled

GastrointestinalGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Colorectal Neoplasms

NCT07292298 2026-02-19

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

44 enrolled

Rectal Neoplasms

NCT07419490 2026-02-19

UOT WPXRT

26 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT03051464 2026-02-17

Morpheus

Phase 2/3 Recruiting

131 enrolled

Rectal Neoplasms

NCT07337876 2026-02-17

MARS

100 enrolled

Rectal Neoplasms

NCT04339374 2026-02-12

Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal Cancer

90 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT07407647 2026-02-12

Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer

GastrointestinalGynecologic

25 enrolled

Anus Neoplasms, Uterine Cervical Neoplasms, Rectal Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms

NCT03516708 2026-02-11

Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

Phase 1/2 Recruiting

49 enrolled

Rectal Neoplasms

NCT06337552 2026-02-09

High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)

54 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Rectal Neoplasms

NCT07227636 2026-02-06

A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy

284 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT07381322 2026-02-06

A Study on the Accurate Evaluation of Pseudoprogression of Rectal Cancer Immunotherapy Based on Multitemporal and Multiparameter MRI

300 enrolled

Rectal Neoplasms

NCT07393048 2026-02-06

ctDNA-MRD-RC

60 enrolled

Rectal Neoplasms

NCT04749108 2026-02-05

GRECCAR14

Phase 2/3 Recruiting

1,075 enrolled

Rectal Neoplasms

NCT04916990 2026-02-05

Improving Care for Rural Patients With Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

320 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Rectal Neoplasms, Thyroid Neoplasms

NCT05652361 2026-02-05

CoBot2

12 enrolled

Rectal Neoplasms

NCT04495088 2026-02-02

Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

Phase 3 Recruiting

550 enrolled

Rectal Neoplasms

NCT07372300 2026-01-28

mEHT

Phase 3 Recruiting

126 enrolled

Hyperthermia, Rectal Neoplasms

NCT04643366 2026-01-27

Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer

54 enrolled

Rectal Neoplasms

NCT06719414 2026-01-27

Application of Amide Proton Transfer-Weighted Imaging in Predicting Pathological Complete Response After Neoadjuvant Therapy of Rectal Cancer

320 enrolled

Rectal Neoplasms

NCT07369830 2026-01-27

The Impact of Probiotic Intervention on the Gut Microbiota and Bowel Function

156 enrolled

Rectal Neoplasms

NCT04165772 2026-01-23

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

200 enrolled

BreastCNSEndocrineGastrointestinalNET

Rectal Neoplasms

NCT05556473 2026-01-23

F-Tryptophan PET/CT in Human Cancers

Phase 1 Recruiting

24 enrolled

Brain Neoplasms, Breast Neoplasms, Rectal Neoplasms, Neuroendocrine Tumors

NCT06914245 2026-01-23

Treatable

150 enrolled

Low Anterior Resection Syndrome, Rectal Neoplasms

NCT02012699 2026-01-22

iCaRe2

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther hematologic neoplasmOther solid neoplasmPlasma cellSarcomaThoracic

999,999 enrolled

Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Duodenal Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Hypopharyngeal Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Leukemia, Lip Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Mouth Neoplasms, Multiple Myeloma, Nasopharyngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Paranasal Sinus Neoplasms, Paraproteinemias, Penile Neoplasms, Peritoneal Neoplasms, Adenomatous Polyposis Coli, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Ureteral Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Central Nervous System Neoplasms, Thyroid Nodule, Endometrial Neoplasms, Neuroendocrine Tumors, Gastrointestinal Stromal Tumors

NCT07359989 2026-01-22

Leucine Plus Radiochemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer

33 enrolled

Rectal Neoplasms

NCT06424522 2026-01-20

A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients

80 enrolled