Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer
Phase 1 Terminated
1 enrolled 7 charts
Preoperative CRT With or Without Induction Chemotherapy for Rectal Cancer With Liver Metastases
Phase 2 Completed
38 enrolled 16 charts
CEDAR
Phase 1 Completed
12 enrolled 13 charts
Talimogene Laherparepvec, Chemotherapy, and Radiation Therapy Before Surgery in Treating Patients With Locally Advanced or Metastatic Rectal Cancer
Phase 1 Terminated
3 enrolled 9 charts
Ipilimumab and Local Radiation for Selected Solid Tumors
Phase 1 Terminated
3 enrolled 5 charts
5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer
Phase 2 Completed
66 enrolled 6 charts
A Phase I Study of AZD6244 in Combination With Capecitabine and Radiotherapy in Locally Advanced Adenocarcinoma of the Rectum
Phase 1 Terminated
1 enrolled 7 charts
BRANCH
Phase 2 Completed
62 enrolled 13 charts
Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer
Phase 1/2 Terminated
32 enrolled 18 charts
Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer
Phase 2 Completed
146 enrolled 23 charts
AXEBEAM
Phase 2 Completed
84 enrolled 19 charts
Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer
Phase 2 Completed
57 enrolled 10 charts
Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer
Phase 3 Completed
225 enrolled 12 charts
Combination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer
Phase 2 Completed
79 enrolled 12 charts
S0713: Oxaliplatin, Capecitabine, Cetuximab, and RT Followed By Surgery in Pts W/Stage II or III Rectal Cancer
Phase 2 Completed
83 enrolled 8 charts
Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal Cancer
Phase 2 Completed
90 enrolled 10 charts
ADAPT
Phase 2 Terminated
27 enrolled 10 charts
A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer
Phase 1/2 Terminated
23 enrolled 18 charts
Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma
Phase 2 Terminated
5 enrolled 6 charts
Pre-op Rectal ChemoRad +/- Cetuximab
Phase 2 Completed
139 enrolled 12 charts
Combination Chemotherapy and Bevacizumab With or Without Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer
Phase NA Completed
35 enrolled 6 charts
Neoadjuvant Chemoradiation With RHUMAB VEGF (Avastin) for Rectal Cancer
Phase 2 Completed
25 enrolled 4 charts