Clinical Trials

240 enrolled 14 charts

Colonic Neoplasms, Rectal Neoplasms

NCT00556413 2026-02-05

Cetuximab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer

42 enrolled

Phase 1/2 Active not recruiting

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04616183 2025-12-23

LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer

46 enrolled

Phase 1/2 Active not recruiting

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04017650 2025-11-20

Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer

38 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Disease Progression

NCT00766142 2025-08-29

COCHISE

GastrointestinalGynecologic

18 enrolled 9 charts

Colonic Neoplasms, Peritoneal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04607421 2025-08-14

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Phase 3 Active not recruiting

831 enrolled 2 FDA

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT06908031 2025-05-14

CRIT

Phase 2 Recruiting

49 enrolled

Phase 3 Active not recruiting

Rectal Neoplasms

NCT04793958 2025-02-11

KRYSTAL-10

461 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT05628038 2024-10-01

TORCH-R

Phase 2 Recruiting

93 enrolled

Phase NA Not yet recruiting

Rectal Neoplasms

NCT06035133 2023-09-13

Treatment of Low Locally Advanced Rectal Cancer With Radiotherapy Removal TNT Plus Neoadjuvant Therapy

213 enrolled

Rectal Neoplasms

NCT00079066 2023-08-04

Cetuximab + Best Supportive Care Compared With Best Supportive Care Alone in Metastatic Epidermal Growth Factor Receptor-Positive Colorectal Cancer

Phase 3 Completed

572 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01079780 2023-06-28

Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy

136 enrolled 13 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01001377 2022-09-21

ASPECCT: A Study of Panitumumab Efficacy and Safety Compared to Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer

Phase 3 Completed

1,010 enrolled 22 charts

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00640081 2021-09-22

Combination Chemotherapy and Cetuximab as First-Line Therapy in Treating Patients With Advanced and/or Metastatic Colorectal Cancer

169 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01280643 2021-03-15

Combination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Phase NA Terminated

3 enrolled 8 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00265850 2020-05-07

Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Completed

2,334 enrolled 9 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01609231 2020-05-04

MK-0646-025

11 enrolled 8 charts

Rectal Neoplasms

NCT00541112 2020-02-11

Radiation Therapy, Chemotherapy, and Cetuximab Followed by Surgery, Chemotherapy, and Cetuximab in Treating Patients With Locally Advanced or Metastatic Rectal Cancer That Can Be Removed by Surgery

19 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00580073 2019-12-13

Phase II Trial of Neoadjuvant FOLFOX4 and Cetuximab for Localized Adenocarcinoma of Rectum

6 enrolled 7 charts

Rectal Neoplasms

NCT01923987 2019-09-20

Short Course Radiotherapy Followed Intensive Chemotherapy With Delayed Surgery for Rectal Cancer With Synchronous Distant Metastasis

Phase 2 Unknown

39 enrolled

Rectal Neoplasms

NCT01310985 2019-03-01

A Trial of Pre-Operative Chemoradiotherapy Using Capecitabine, Radiation & Cetuximab, in Rectal Cancer

Completed

15 enrolled

GastrointestinalHead & Neck

Rectal Neoplasms

NCT02205398 2019-01-22

Study of Safety and Efficacy of INC280 and Cetuximab, in Adult c-MET Positive mCRC and HNSCC Patients After Progression on Cetuximab or Panitumumab Therapy

Phase 1 Terminated

13 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Laryngeal Diseases, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00611858 2019-01-08

Cetuximab, 5-FU and Radiation as Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer

13 enrolled 9 charts

Rectal Neoplasms

NCT00686166 2018-05-18

S0713: Oxaliplatin, Capecitabine, Cetuximab, and RT Followed By Surgery in Pts W/Stage II or III Rectal Cancer

83 enrolled 8 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT00077233 2018-05-16

FOLFIRI or FOLFOX With or Without Cetuximab in Patients With Metastatic Adenocarcinoma of the Colon or Rectum

Phase 3 Terminated

238 enrolled

Phase 2 Active not recruiting

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT03391843 2018-01-05

Neoadjuvant Chemotherapy Combined With Cetuximab for EGFR Wild Type Locally Advanced Rectal Cancer

100 enrolled

Rectal Neoplasms

NCT00226941 2017-12-08

A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer

Phase 1/2 Terminated

23 enrolled 18 charts

Colonic Neoplasms, Rectal Neoplasms

NCT00326495 2017-07-24

BAY 43-9006 Plus Cetuximab to Treat Colorectal Cancer

51 enrolled 11 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00056030 2017-01-24

Combination Chemotherapy Plus Cetuximab in Treating Patients With Liver Metastases From Colorectal Cancer

73 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00527111 2016-11-03

Pre-op Rectal ChemoRad +/- Cetuximab

139 enrolled 12 charts

Rectal Neoplasms

NCT00336856 2016-07-12

Irinotecan and Cetuximab for Colorectal Cancer as Second Line Therapy

35 enrolled 7 charts

Colonic Neoplasms, Rectal Neoplasms

NCT00571740 2016-07-06

Cetuximab and Bevacizumab as First-Line Therapy Followed By Combination Chemotherapy and Bevacizumab With or Without Cetuximab as Second-Line Therapy in Treating Patients With Stage IV Colorectal Cancer

Phase 2 Withdrawn

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00084773 2015-12-22

Neoadjuvant Cetuximab, Fluorouracil, and Pelvic Irradiation in Treating Patients With Locally Advanced or Locally Recurrent Rectal Cancer

Phase NA Completed

28 enrolled

CNSGastrointestinalHead & NeckSarcomaThoracic

Rectal Neoplasms, Colorectal Neoplasms

NCT00397384 2015-09-30

Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer

Phase 1 Completed

43 enrolled

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Pancreatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Tongue Neoplasms, Esthesioneuroblastoma, Olfactory, Gastrointestinal Stromal Tumors

NCT00100841 2015-07-27

Phase II Trial of FOLFOX6, Bevacizumab and Cetuximab in Patients With Colorectal Cancer

66 enrolled 7 charts

Colonic Neoplasms, Rectal Neoplasms

NCT01198535 2015-05-18

Phase I Study of Cetuximab With RO4929097 in Metastatic Colorectal Cancer

Phase 1 Terminated

60 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT00077298 2015-04-15

Bevacizumab and Cetuximab With or Without Irinotecan in Treating Patients With Irinotecan-Refractory Metastatic Colorectal Cancer

70 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT00551421 2015-03-31

Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer

Phase 1/2 Completed

17 enrolled 7 charts

Colonic Neoplasms, Rectal Neoplasms

NCT00538291 2014-08-28

Cetuximab and Capecitabine in Treating Patients With Metastatic Colorectal Cancer That Failed Irinotecan Treatment

13 enrolled 5 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00499369 2014-07-31

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy

Phase 3 Terminated

72 enrolled 15 charts

CNSGastrointestinalGenitourinaryHead & NeckThoracic

Colonic Neoplasms, Rectal Neoplasms

NCT00101348 2014-06-11

Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney, Colorectal, Head and Neck, Pancreatic, or Non-Small Cell Lung Cancer

Phase 1/2 Completed

66 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Esthesioneuroblastoma, Olfactory

NCT01217450 2014-05-29

Selumetinib and Cetuximab in Treating Patients With Refractory Solid Tumors

Phase 1 Completed

33 enrolled

Phase EARLY_PHASE1 Terminated

Colonic Neoplasms, Rectal Neoplasms

NCT00835679 2014-05-23

Cetuximab and/or Dasatinib in Patients With Colorectal Cancer and Liver Metastases That Can Be Removed by Surgery

9 enrolled 3 charts

Colonic Neoplasms, Rectal Neoplasms

NCT00134069 2014-04-16

Sorafenib, Cetuximab, and Irinotecan in Treating Patients With Advanced or Metastatic Colorectal Cancer

Phase 1 Completed

48 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT00795301 2014-01-14

A Study of Radiotherapy in Rectal Cancer Using Oxaliplatin, Capecitabine With or Without Cetuximab

Phase 2 Unknown

74 enrolled

Neoplasms, Rectal Neoplasms

NCT00975897 2013-12-19

Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer

Phase 2/3 Completed

3,240 enrolled