Clinical Trials Browser

INDUSTRY × Rectal Neoplasms × Irinotecan × Clear all

NCT06607185 2026-03-13

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

Phase 1 Active not recruiting

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT04607421 2025-08-14

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Phase 3 Active not recruiting

831 enrolled 2 FDA

Gastrointestinal

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT01394939 2021-01-08

Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma

Phase 1/2 Completed

52 enrolled 13 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Vaccinia, Colorectal Neoplasms

NCT01609231 2020-05-04

MK-0646-025

Phase 2 Terminated

11 enrolled 8 charts

Gastrointestinal

Rectal Neoplasms

NCT00418938 2018-10-17

SPIRITT - Second-Line Panitumumab Irinotecan Treatment Trial

Phase 2 Completed

266 enrolled 17 charts

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00816777 2018-09-07

PARAGON

Phase 1/2 Terminated

4 enrolled 5 charts

Gastrointestinal

Carcinoma, Colonic Neoplasms, Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT03607643 2018-07-31

A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies

Phase 1/2 Unknown

CNSGastrointestinalPlasma cell

Colonic Neoplasms, Gallbladder Neoplasms, Glioblastoma, Liver Neoplasms, Multiple Myeloma, Pancreatic Neoplasms, Rectal Neoplasms

NCT00022698 2016-04-15

Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer

Phase 2 Completed

67 enrolled 15 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00332163 2016-02-23

STEPP

Phase 2 Completed

95 enrolled 23 charts

Gastrointestinal

Colonic Neoplasms, Exanthema, Rectal Neoplasms, Colorectal Neoplasms

NCT00026273 2012-08-07

Fluorouracil and Leucovorin With or Without Irinotecan in Treating Patients Following Surgery for Stage III Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00006269 2012-05-25

Octreotide in the Prevention of Diarrhea in Patients Receiving Irinotecan for Metastatic Colon Cancer

Phase 3 Terminated

Gastrointestinal

Colonic Neoplasms, Diarrhea, Rectal Neoplasms, Colorectal Neoplasms