Clinical Trials

Phase 2/3 Not yet recruiting

Rectal Neoplasms

NCT07134218 2025-08-21

Neoadjuvant Chemoradiotherapy Combined With Immunotherapy and Anti-angiogenesis in Treating Locally Advanced Rectal Cancer

180 enrolled

Rectal Neoplasms

NCT05496491 2024-10-08

Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial

Phase NA Recruiting

84 enrolled

Phase 3 Not yet recruiting

Neoplasms, Rectal Neoplasms

NCT06097416 2023-10-25

Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer

100 enrolled

Rectal Neoplasms

NCT05984485 2023-08-09

TaLaR-02

Phase 3 Recruiting

766 enrolled

Rectal Neoplasms

NCT01444495 2023-02-15

Randomized Clinical Trial on Preoperative Radiotherapy 25 Gy in Rectal Cancer

154 enrolled

Rectal Neoplasms

NCT05592873 2022-10-25

I-ONARC

317 enrolled

Rectal Neoplasms

NCT05496270 2022-08-11

Surgery Alone Versus Neoadjuvant Treatment Followed by Surgery For MRI-defined T3 Mid-low Rectal Cancer

1,509 enrolled

Rectal Neoplasms

NCT05495308 2022-08-10

"Oncologic Results and Risk Factors for Recurrence in Patients With Locally Advanced Rectal Cancer and Pathologic Complete Response After Neoadjuvant Treatment. Results From an Observational Retrospective Multicenter Long-term Follow-up Study".

4 enrolled

Rectal Neoplasms

NCT05339763 2022-04-21

Long Term Bowel Function Following Rectal Cancer Surgery

171 enrolled

Rectal Neoplasms, Irritable Bowel Syndrome

NCT02533271 2021-07-16

STELLAR

Phase 3 Unknown

600 enrolled

Rectal Neoplasms

NCT00227747 2021-02-17

Radiation Therapy and Capecitabine With or Without Oxaliplatin in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Rectal Cancer

Phase 3 Completed

598 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00541112 2020-02-11

Radiation Therapy, Chemotherapy, and Cetuximab Followed by Surgery, Chemotherapy, and Cetuximab in Treating Patients With Locally Advanced or Metastatic Rectal Cancer That Can Be Removed by Surgery

Phase 2 Terminated

19 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT03899870 2019-04-02

Factors Predicting Recurrence in Rectal Cancer After Surgery

188 enrolled

Rectal Neoplasms, Recurrence

NCT00114231 2018-03-29

Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal Cancer

90 enrolled 10 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT00625183 2017-11-17

Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma

Phase 2 Terminated

5 enrolled 6 charts

Rectal Neoplasms, Colorectal Neoplasms

NCT00408772 2017-06-09

Oxaliplatin, Capecitabine, and Bevacizumab Followed By Surgery and/or Radiofrequency Ablation in Patients With Colorectal Cancer

Phase 2 Withdrawn

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT03151759 2017-05-12

MMP-7

77 enrolled

Rectal Neoplasms

NCT01263171 2016-09-21

COPERNICUS

60 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00216086 2016-06-06

Capecitabine + Irinotecan Followed by Combined Modality Capecitabine and Radiation in Locally Advanced Rectal Cancer

Phase 2 Terminated

22 enrolled 10 charts

Rectal Neoplasms

NCT00004891 2015-12-22

PET and CT Scans in Patients With Locally Advanced Primary Rectal Cancer That Can Be Removed During Surgery

149 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00084773 2015-12-22

Neoadjuvant Cetuximab, Fluorouracil, and Pelvic Irradiation in Treating Patients With Locally Advanced or Locally Recurrent Rectal Cancer

28 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00967655 2014-01-10

Capecitabine, Panitumumab, and Radiation Therapy With or Without Irinotecan Hydrochloride in Treating Patients Undergoing Surgery for Localized Rectal Cancer

54 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00003422 2013-12-04

Radiation Therapy Before Surgery Compared With Chemotherapy Plus Radiation After Surgery in Treating Patients With Rectal Cancer That Can Be Surgically Removed

Phase 3 Completed

1,800 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00909987 2013-10-11

Study of Neoadjuvant CT With Selective Radiotherapy in Patients With Intermediate-Risk Cancer Rectum

46 enrolled

Rectal Neoplasms

NCT01086618 2013-08-26

Chemotherapy With or Without Surgery in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Phase 2/3 Completed

500 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00005616 2013-06-19

Monoclonal Antibody Therapy in Treating Patients With Colorectal Cancer

Phase 1 Completed

12 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00960427 2013-04-16

Studying Biomarkers in Tumor Tissue and Blood Samples From Patients Undergoing Chemotherapy and Radiation Therapy for Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery

Phase 1 Withdrawn

Rectal Neoplasms, Colorectal Neoplasms

NCT00086931 2013-03-08

Oxaliplatin, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Rectum

Phase 1/2 Completed

37 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00608595 2013-03-05

Celecoxib in Treating Patients With Early-Stage Rectal Cancer

Phase NA Terminated

10 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00482222 2013-01-23

Combination Chemotherapy With or Without Cetuximab Before and After Surgery in Treating Patients With Resectable Liver Metastases Caused By Colorectal Cancer

Phase 3 Unknown

340 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00438737 2011-09-02

Cetuximab, Leucovorin, Oxaliplatin, and Fluorouracil With or Without Bevacizumab in Treating Patients With Resectable Liver Metastases From Colorectal Cancer

100 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00392470 2011-05-25

Radiation Therapy, Irinotecan, and Cetuximab in Treating Patients Who Are Undergoing Surgery for Stage III or Stage IV Rectal Cancer

Phase 1 Unknown

20 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00006479 2011-04-18

Surgery With or Without Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer

Phase 3 Unknown

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00084591 2010-02-12

Intensity-Modulated Radiation Therapy With Incorporated Boost and Capecitabine Before Surgery in Treating Patients With Locally Advanced Rectal Cancer

Phase 1 Completed

Rectal Neoplasms, Colorectal Neoplasms

NCT00383695 2010-01-13

EXPERT-C

164 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT00513266 2009-08-07

Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Advanced Colorectal Cancer With Liver Metastases or Lung Metastases That Are Potentially Removable by Surgery

35 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00072553 2009-02-09

Celecoxib, Leucovorin, Fluorouracil, and Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00075556 2009-02-09

Neoadjuvant Radiation Therapy and Capecitabine in Treating Patients With Stage III or Stage IV Colorectal Adenocarcinoma

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00268333 2009-02-09

Combination Chemotherapy and Radiation Therapy in Treating Patients With Recurrent Metastatic Colorectal Cancer

39 enrolled