Clinical Trials

442 enrolled

Rectal Neoplasms, Anastomotic Leak

NCT07176182 2026-02-27

Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression

236 enrolled

Rectal Neoplasms

NCT07369531 2026-02-27

RC09-FIAS

498 enrolled

Neoplasms, Rectal Neoplasms

NCT07429110 2026-02-24

ColoSeal™ ICD System Anastomotic Protection Pivotal Study

250 enrolled

Rectal Neoplasms

NCT06123156 2026-02-18

RECTIL

188 enrolled

Rectal Neoplasms

NCT07410767 2026-02-18

Advanced Endoscopic Resections for Rectal Neoplasms

300 enrolled

Rectal Neoplasms

NCT07292285 2026-02-17

SNOWW

200 enrolled

Rectal Neoplasms

NCT07113275 2026-02-12

A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in High-Risk Locally Advanced Rectal Cancer

435 enrolled

Rectal Neoplasms

NCT07397442 2026-02-11

Short-Course Radiotherapy Combined With Chemotherapy and Immunotherapy in Mid-Low Locally Advanced Rectal Cancer

19 enrolled

Pathologic Complete Response, Rectal Neoplasms

NCT07402486 2026-02-11

A Phase II Prospective Study of Maastro Applicator Brachytherapy for Rectal Cancer

20 enrolled

Rectal Neoplasms

NCT07404228 2026-02-11

RESTAGE

115 enrolled

Rectal Neoplasms

NCT07394192 2026-02-06

PKUCH- R11

44 enrolled

Rectal Neoplasms

NCT07381400 2026-02-03

Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally Advanced Rectal Cancer (FIRM02 Study)

128 enrolled

Rectal Neoplasms

NCT07363863 2026-01-23

Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma

100 enrolled

Rectal Neoplasms

NCT07358247 2026-01-22

NOSE

190 enrolled

Rectal Neoplasms

NCT07209215 2026-01-20

ULTIMATE

200 enrolled

Rectal Neoplasms

NCT07346586 2026-01-16

Effect of Individualized Catheter Management on Early Removal After Rectal Cancer Surgery

1,545 enrolled

Rectal Neoplasms, Urinary Retention

NCT07345273 2026-01-15

RADAR

225 enrolled

Phase 2/3 Not yet recruiting

Rectal Neoplasms

NCT07321847 2026-01-07

INJECTABL-3

717 enrolled

Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07306390 2025-12-29

DIAMOND

1,200 enrolled

Colonic Neoplasms, Lymphatic Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT07302126 2025-12-24

Preventive Efficacy of Bergmann Enema for Acute Radiation-induced Rectal Injury in Rectal Cancer Patients Undergoing Short-course Radiotherapy

40 enrolled

Rectal Neoplasms

NCT07297030 2025-12-22

SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer

37 enrolled

Rectal Neoplasms

NCT07283939 2025-12-16

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

420 enrolled

Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT07281768 2025-12-15

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

66 enrolled

Adenocarcinoma, Carcinoma, Rectal Neoplasms, Colorectal Neoplasms

NCT07269912 2025-12-08

Application of Multimodal MRI in Histological Grading and Prognostic Assessment of Rectal Cancer

400 enrolled

Rectal Neoplasms

NCT07258797 2025-12-02

SHOOL

150 enrolled

Rectal Neoplasms

NCT07253298 2025-11-28

BFT in LARS

66 enrolled

Low Anterior Resection Syndrome, Intestinal Diseases, Rectal Neoplasms

NCT07248020 2025-11-25

BCMRECRAD

72 enrolled

Rectal Neoplasms

NCT07239466 2025-11-20

A Pilot Study Evaluating β-hydroxybutyrate Supplementation Concomitant to Short-Course Radiotherapy Followed by Immunotherapy Combined With CAPEOX Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer

48 enrolled

Rectal Neoplasms

NCT07236827 2025-11-19

ESISD vs CESD

60 enrolled

Rectal Neoplasms

NCT07192627 2025-09-25

ESD in Locally Advanced Rectal Cancer Following CRT

20 enrolled

Rectal Neoplasms

NCT07188025 2025-09-23

REACT

103 enrolled

Rectal Neoplasms

NCT07183124 2025-09-19

3D Modeling for Detecting Locally Advanced Rectal Cancer With Positive Circumferential Resection Margin

1,500 enrolled

Neoplasms, Rectal Neoplasms

NCT06929338 2025-09-16

xDRIVE in Metastatic Colorectal Cancer

30 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07143487 2025-09-16

Family Communications After Genetic Testing

4,186 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07175636 2025-09-16

QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer

66 enrolled

Rectal Neoplasms

NCT07161115 2025-09-15

REFIRT

60 enrolled

Rectal Neoplasms

NCT07162714 2025-09-09

STAR

30 enrolled

Rectal Neoplasms

NCT07146334 2025-08-28

OASIS

400 enrolled

Phase 2/3 Not yet recruiting

Rectal Neoplasms, Anastomotic Leak

NCT07134218 2025-08-21

Neoadjuvant Chemoradiotherapy Combined With Immunotherapy and Anti-angiogenesis in Treating Locally Advanced Rectal Cancer

180 enrolled

Rectal Neoplasms

NCT07134296 2025-08-21

Magnetic Resonance Imaging (MRI)-Guided Rectal Cancer Preservation Program

32 enrolled

Rectal Neoplasms

NCT07132463 2025-08-20

Neoadjuvant Chemoradiotherapy Followed by Chemotherapy With or Without Tislelizumab for Resectable Ultra-low Rectal Cancer: The RELIEVE-02 Study

154 enrolled

Rectal Neoplasms

NCT07080411 2025-07-23

the Efficacy of MR-guided Online Adaptive Radiotherapy for Locally Advanced Rectal Cancer

49 enrolled

Rectal Neoplasms

NCT07054047 2025-07-08

MERCURY 3

438 enrolled

Gastrointestinal Neoplasms, Rectal Neoplasms

NCT06936774 2025-07-03

iRECOVER

140 enrolled

Low Anterior Resection Syndrome, Rectal Neoplasms

NCT06823297 2025-06-27

CANO

436 enrolled

Rectal Neoplasms

NCT07041515 2025-06-27

Knowledge-enhanced Digital Intervention to Prevent Low Anterior Resection Syndrome

320 enrolled

Low Anterior Resection Syndrome, Rectal Neoplasms

NCT06850090 2025-06-25

Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial

210 enrolled

Rectal Neoplasms

NCT07035600 2025-06-25

WASA

300 enrolled