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1 trials

Recent Start date Enrollment

Phase 1 × Recurrence × MLN 8237 × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Conditions

Lymphoma 6 Lymphoma, Mantle-Cell 3 Lymphoma, Follicular 3 Burkitt Lymphoma 3 Pancreatic Neoplasms 2 Lymphoma, T-Cell 2 Lymphoma, Large B-Cell, Diffuse 2 Lymphoma, B-Cell 2 Hodgkin Disease 2 Head and Neck Neoplasms 2 Gastrointestinal Neoplasms 2 Advanced Solid Tumors 2 Advanced Nonhematologic Malignancies 2 Advanced Malignancies 2 Waldenstrom Macroglobulinemia 1 Small Cell Lung Carcinoma 1 Sezary Syndrome 1 Recurrence 1 Rectal Neoplasms 1 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1 Precursor Cell Lymphoblastic Leukemia-Lymphoma 1 Ovarian Neoplasms 1 Oligodendroglioma 1 Neuroblastoma 1 Mycosis Fungoides 1 Melanoma 1 Malignant Neoplasms of Digestive Organs 1 Lymphoma, T-Cell, Cutaneous 1 Lymphoma, Non-Hodgkin 1 Lymphoma, Large-Cell, Immunoblastic 1

Interventions

Cyclophosphamide 39 fludarabine 28 Dexamethasone 23 venetoclax 19 Cytarabine 17 Rituximab 14 pembrolizumab 12 fludarabine phosphate 12 Filgrastim 12 Etoposide 11 Gemcitabine 10 Lenalidomide 9 Granulocyte Colony-Stimulating Factor 9 carfilzomib 8 Vincristine 8 Topotecan 8 Interleukin-2 8 Decitabine 8 pomalidomide 7 Nivolumab 7 Melphalan 7 Everolimus 7 Doxorubicin 7 Calcium Dobesilate 7 Bortezomib 7 Azacitidine 7 Vorinostat 6 Methotrexate 6 Injections 6 Carboplatin 6

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT02780011 2018-07-27

AD3LE

The Methodist Hospital Research Institute

Phase 1 Withdrawn

Recurrence

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