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Phase 2 × Recurrence × binimetinib × Clear all

Phase

Phase 2 1 Phase 1/2 1

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Melanoma 17 Brain Neoplasms 6 Carcinoma, Non-Small-Cell Lung 5 Neoplasms 4 Pancreatic Neoplasms 3 Neoplasm Metastasis 3 Lung Neoplasms 3 Colorectal Neoplasms 3 Ovarian Neoplasms 2 Multiple Myeloma 2 Leukemia, Hairy Cell 2 Hematologic Neoplasms 2 Triple Negative Breast Neoplasms 1 Thyroid Neoplasms 1 Skin Neoplasms 1 Recurrence 1 Peripheral Nervous System Neoplasms 1 Noonan Syndrome 5 1 Neurofibromatosis 1 1 Neurofibromatoses 1 Neurofibroma, Plexiform 1 Neurofibroma 1 Lymphoma 1 Lymphatic Metastasis 1 Leukemia, Myeloid, Acute 1 Hereditary Sensory and Autonomic Neuropathies 1 Gliosarcoma 1 Glioma 1 Glioblastoma 1 Fallopian Tube Neoplasms 1

Interventions

Cyclophosphamide 53 Dexamethasone 40 Rituximab 35 Paclitaxel 25 Lenalidomide 25 Peripheral Blood Stem Cell Transplantation 24 Gemcitabine 23 Etoposide 23 fludarabine phosphate 22 Cytarabine 22 Busulfan 22 Bevacizumab 21 Bortezomib 20 pembrolizumab 19 Radiotherapy 19 Melphalan 18 fludarabine 16 Oxaliplatin 16 Mycophenolic Acid 16 Cisplatin 16 Carboplatin 16 Filgrastim 15 Cyclosporine 15 pomalidomide 14 Antilymphocyte Serum 14 Whole-Body Irradiation 13 Methotrexate 13 Methylprednisolone 12 Bendamustine Hydrochloride 12 Tacrolimus 11

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT02834364 2023-11-24

GMMG-BIRMA

University of Heidelberg Medical Center

Phase 2 Completed

Multiple Myeloma, Recurrence

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