Clinical Trials Browser

Mast Cell Activation Disorders, Carcinoma, Non-Small-Cell Lung, Glioma, Leukemia, Mast-Cell, Melanoma, Neoplasms, Germ Cell and Embryonal, Penile Neoplasms, Sarcoma, Mastocytosis, Systemic, Gastrointestinal Stromal Tumors, Renal Insufficiency

NCT01575925 2022-11-04

POM Renal

Phase 1 Completed

25 enrolled

Plasma cell

Multiple Myeloma, Renal Insufficiency

NCT03172884 2021-04-28

Study of Copanlisib in Hepatic or Renal Impairment

Phase 1 Completed

30 enrolled 20 charts

Hepatic Insufficiency, Renal Insufficiency

NCT02679131 2019-11-20

To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.

Phase 1 Terminated

18 enrolled

Other hematologic neoplasm

Recurrence, Hematologic Neoplasms, Renal Insufficiency

NCT00652626 2019-11-19

RENAL

Phase 1 Completed

31 enrolled 30 charts

LymphoidPlasma cell

Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Renal Insufficiency

NCT03097016 2018-04-26

A Study to Assess the Pharmacokinetics of CC-122 in Subjects With Mild, Moderate, and Severe Renal Impairment

Phase 1 Completed

48 enrolled

Lymphoid

Lymphoma, Follicular, Renal Insufficiency

NCT00483860 2017-11-13

A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal Function

Phase 1 Completed

59 enrolled

Neoplasms, Renal Insufficiency

NCT01331941 2017-11-06

A Pharmacokinetic Study of AMG 386 in Cancer Subjects With Normal and Impaired Renal Function

Phase 1 Completed

35 enrolled

Genitourinary

Kidney Diseases, Renal Insufficiency

NCT01853046 2017-02-20

Pharmacokinetics and Safety of Regorafenib (BAY73-4506) in Cancer Subjects With Severe Renal Impairment

Phase 1 Completed

24 enrolled 30 charts

Neoplasms, Renal Insufficiency

NCT01569815 2015-10-19

Pharmacokinetics of LCZ696 in Subjects With Mild and Moderate Renal Impairment Compared to Healthy Subjects With Normal Renal Function

Phase 1 Completed

32 enrolled 16 charts

Lymphoid

Lymphoma, Follicular, Renal Insufficiency

NCT00418366 2015-08-19

A Study on the Effect of Kidney Disease on a Diabetes Medication (0431-008)

Phase 1 Completed

24 enrolled

GenitourinaryLymphoid

Kidney Failure, Chronic, Lymphoma, Follicular, Renal Insufficiency

NCT02063204 2015-06-30

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Renal Impaired Subjects and Healthy Subjects

Phase 1 Completed

24 enrolled

Renal Insufficiency

NCT01504165 2014-02-04

Pharmacokinetics in Subjects With Renal Impairment

Phase 1 Completed

32 enrolled

Lymphoid

Lymphoma, Follicular, Renal Insufficiency

NCT00750620 2013-09-05

A Pharmacokinetic Study of YM178 in Normal Subjects and Those With Mild, Moderate, and Severe Renal Impairment

Phase 1 Completed

33 enrolled

Lymphoid

Lymphoma, Follicular, Renal Insufficiency

NCT01374113 2013-03-29

Safinamide Renal Impairment Trial

Phase 1 Completed

24 enrolled

Lymphoid

Lymphoma, Follicular, Renal Insufficiency

Clinical Trials

DREAMM12

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Study of Rubitecan in Cancer Patients With Renal or Hepatic Dysfunction

A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies

POM Renal

Study of Copanlisib in Hepatic or Renal Impairment

To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.

RENAL

A Study to Assess the Pharmacokinetics of CC-122 in Subjects With Mild, Moderate, and Severe Renal Impairment

A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal Function

A Pharmacokinetic Study of AMG 386 in Cancer Subjects With Normal and Impaired Renal Function

Pharmacokinetics and Safety of Regorafenib (BAY73-4506) in Cancer Subjects With Severe Renal Impairment

Pharmacokinetics of LCZ696 in Subjects With Mild and Moderate Renal Impairment Compared to Healthy Subjects With Normal Renal Function

A Study on the Effect of Kidney Disease on a Diabetes Medication (0431-008)

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Renal Impaired Subjects and Healthy Subjects

Pharmacokinetics in Subjects With Renal Impairment

A Pharmacokinetic Study of YM178 in Normal Subjects and Those With Mild, Moderate, and Severe Renal Impairment

Safinamide Renal Impairment Trial