Clinical Trials Browser

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT03172624 2025-12-18

Study of Nivolumab Plus Ipilimumab in Patients With Salivary Gland Cancer

Phase 2 Completed

64 enrolled 9 charts

Head & Neck

Salivary Gland Neoplasms

NCT02576431 2025-11-12

NAVIGATE

Phase 2 Completed

215 enrolled 3 FDA

BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Salivary Gland Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT00559156 2025-02-13

Arginine/Omega-3 Fatty Acids/Nucleotides Nutritional Supplement in Treating Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy

Phase 2 Completed

46 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT01969578 2024-11-05

Androgen Deprivation Therapy in Advanced Salivary Gland Cancer

Phase 2 Completed

149 enrolled

Head & Neck

Adenocarcinoma, Salivary Gland Neoplasms, Bulbo-Spinal Atrophy, X-Linked

NCT01703455 2023-10-19

Activity of Sorafenib in Salivary Gland Cancer

Phase 2 Completed

37 enrolled

Head & Neck

Salivary Gland Neoplasms

NCT00079079 2023-08-04

Cisplatin or Carboplatin Combined With Gemcitabine in Locally Advanced, Recurrent, or Metastatic Malignant Salivary Gland Tumor

Phase 2 Completed

34 enrolled

Head & Neck

Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT00040807 2023-06-18

Irinotecan and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer

Phase 2 Completed

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT00002632 2023-06-15

Paclitaxel in Treating Patients With Metastatic or Recurrent Salivary Gland Cancer

Phase 2 Completed

32 enrolled

Head & Neck

Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT04291300 2023-05-10

LUPSA

Phase 2 Completed

12 enrolled

Head & Neck

Carcinoma, Adenoid Cystic, Salivary Gland Neoplasms

NCT03132038 2022-01-11

NISCAHN

Phase 2 Completed

98 enrolled

Head & Neck

Neoplasm Metastasis, Recurrence, Salivary Gland Neoplasms

NCT01175980 2020-08-03

Vorinostat in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma

Phase 2 Completed

30 enrolled 16 charts

Head & Neck

Salivary Gland Neoplasms, Tongue Neoplasms

NCT00524017 2020-03-12

Cetuximab in Treating Patients With Precancerous Lesions of the Upper Aerodigestive Tract

Phase 2 Completed

35 enrolled 6 charts

Head & NeckOther neoplasm

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Precancerous Conditions, Salivary Gland Neoplasms

NCT02393820 2019-10-29

PACSA-ORL02

Phase 2 Completed

72 enrolled

Head & Neck

Salivary Gland Neoplasms

NCT02857712 2019-08-30

SGC-AX14

Phase 2 Completed

26 enrolled

Head & Neck

Salivary Gland Neoplasms

NCT01604772 2019-05-01

Akt Inhibitor MK2206 in Treating Patients With Progressive, Recurrent, or Metastatic Adenoid Cyst Carcinoma

Phase 2 Completed

16 enrolled 7 charts

Head & Neck

Salivary Gland Neoplasms

NCT02123511 2019-04-30

Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy

Phase 2 Completed

34 enrolled 16 charts

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms, Mucositis

NCT00045669 2019-02-15

Imatinib Mesylate in Treating Patients With Salivary Gland Cancer

Phase 2 Completed

16 enrolled

Head & Neck

Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT01613768 2018-09-28

Eribulin Mesylate in Treating Patients With Recurrent or Metastatic Salivary Gland Cancer

Phase 2 Completed

29 enrolled 12 charts

Head & Neck

Salivary Gland Neoplasms

NCT00509665 2018-07-12

Gemcitabine and Doxorubicin in Treating Patients With Recurrent or Progressive Head and Neck Cancer

Phase 2 Completed

18 enrolled 9 charts

CNSHead & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00859937 2018-04-20

Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland Tumors

Phase 2 Completed

55 enrolled 8 charts

Head & Neck

Salivary Gland Neoplasms

NCT00052611 2018-03-29

Celecoxib in Preventing Cancer in Patients With Oral Leukoplakia and/or Head and Neck Dysplasia

Phase 2 Completed

23 enrolled

Head & Neck

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Salivary Gland Neoplasms

NCT01316757 2018-02-26

Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Head and Neck Squamous Cell Cancer

Phase 2 Completed

24 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT00509002 2017-11-24

Iressa Study in Patients With Salivary Gland Cancer

Phase 2 Completed

37 enrolled 4 charts

Head & Neck

Salivary Gland Neoplasms

NCT00004163 2017-04-18

Trastuzumab in Treating Patients With Advanced Salivary Gland Cancer

Phase 2 Completed

14 enrolled

Head & Neck

Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT00095563 2017-04-18

Lapatinib in Treating Patients With Recurrent and/or Metastatic Adenoid Cystic Cancer or Other Salivary Gland Cancers

Phase 2 Completed

40 enrolled 9 charts

Head & Neck

Salivary Gland Neoplasms

NCT01256385 2017-03-27

MAESTRO HN

Phase 2 Completed

86 enrolled 11 charts

Head & Neck

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT00095628 2017-03-06

SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Phase 2 Completed

21 enrolled 10 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms

NCT00003744 2017-01-19

Gemcitabine in Treating Patients With Advanced Salivary Gland Cancer That Cannot Be Removed During Surgery

Phase 2 Completed

16 enrolled

Head & Neck

Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT00448552 2016-12-15

Oxaliplatin and Capecitabine in Treating Patients With Relapsed or Metastatic Head and Neck Cancer

Phase 2 Completed

30 enrolled

CNSHead & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00003565 2016-07-14

Docetaxel in Treating Patients With Solid Tumors

Phase 2 Completed

109 enrolled

BreastCNSGenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Neoplasms, Nasopharyngeal Neoplasms, Salivary Gland Neoplasms, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT01678105 2015-09-17

DOVE

Phase 2 Completed

21 enrolled

Head & Neck

Salivary Gland Neoplasms

NCT00458978 2015-05-05

Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer

Phase 2 Completed

6 enrolled

Head & Neck

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT00114283 2015-04-15

Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Phase 2 Completed

30 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT00507767 2014-10-01

Dasatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Phase 2 Completed

15 enrolled 8 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT00049140 2014-07-25

EF5 Compared With Other Methods of Detecting Oxygen Levels in Tumor Cells of Patients With Head and Neck Cancer

Phase 2 Completed

8 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT00492089 2014-05-09

Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

Phase 2 Completed

11 enrolled 7 charts

CNSHead & Neck

Hemangiopericytoma, Malignant, Squamous Cell Carcinoma of Head and Neck, Astrocytoma, Brain Neoplasms, Ependymoma, Glioma, Meningioma, Neoplasms, Oligodendroglioma, Pinealoma, Radiation Injuries, Salivary Gland Neoplasms, Choroid Plexus Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00019331 2013-06-20

Vaccine Therapy Plus Biological Therapy in Treating Adults With Metastatic Solid Tumors

Phase 2 Completed

CNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Salivary Gland Neoplasms, Testicular Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Adenocarcinoma, Follicular, Carcinoma, Medullary, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma, Thyroid Carcinoma, Anaplastic

NCT00020189 2013-06-19

Flavopiridol in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Phase 2 Completed

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms, Thromboembolism

NCT00033618 2013-02-27

Ixabepilone in Treating Patients With Metastatic or Recurrent Squamous Cell Cancer of the Head and Neck

Phase 2 Completed

144 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT00077428 2013-01-24

Bortezomib Followed by the Addition of Doxorubicin at Disease Progression in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma (Cancer) of the Head and Neck

Phase 2 Completed

37 enrolled

Head & Neck

Salivary Gland Neoplasms

NCT00017498 2012-09-24

Gemcitabine in Treating Patients With Recurrent or Metastatic Adenoid Cystic Cancer of the Head and Neck

Phase 2 Completed

21 enrolled

Head & Neck

Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT00639769 2012-09-14

Irinotecan and Cisplatin in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Phase 2 Completed

41 enrolled 8 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT00058006 2012-06-11

Celecoxib in Treating Patients With Early-Stage Head and Neck Cancer or Non-Small Cell Lung Cancer

Phase 2 Completed

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Neoplasms, Salivary Gland Neoplasms

NCT00738868 2011-05-13

Cetuximab and Stereotactic Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer That Cannot Be Removed By Surgery

Phase 2 Completed

45 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms

Clinical Trials

Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab

Study of Nivolumab Plus Ipilimumab in Patients With Salivary Gland Cancer

NAVIGATE

Arginine/Omega-3 Fatty Acids/Nucleotides Nutritional Supplement in Treating Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy

Androgen Deprivation Therapy in Advanced Salivary Gland Cancer

Activity of Sorafenib in Salivary Gland Cancer

Cisplatin or Carboplatin Combined With Gemcitabine in Locally Advanced, Recurrent, or Metastatic Malignant Salivary Gland Tumor

Irinotecan and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer

Paclitaxel in Treating Patients With Metastatic or Recurrent Salivary Gland Cancer

LUPSA

NISCAHN

Vorinostat in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma

Cetuximab in Treating Patients With Precancerous Lesions of the Upper Aerodigestive Tract

PACSA-ORL02

SGC-AX14

Akt Inhibitor MK2206 in Treating Patients With Progressive, Recurrent, or Metastatic Adenoid Cyst Carcinoma

Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy

Imatinib Mesylate in Treating Patients With Salivary Gland Cancer

Eribulin Mesylate in Treating Patients With Recurrent or Metastatic Salivary Gland Cancer

Gemcitabine and Doxorubicin in Treating Patients With Recurrent or Progressive Head and Neck Cancer

Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland Tumors

Celecoxib in Preventing Cancer in Patients With Oral Leukoplakia and/or Head and Neck Dysplasia

Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Head and Neck Squamous Cell Cancer

Iressa Study in Patients With Salivary Gland Cancer

Trastuzumab in Treating Patients With Advanced Salivary Gland Cancer

Lapatinib in Treating Patients With Recurrent and/or Metastatic Adenoid Cystic Cancer or Other Salivary Gland Cancers

MAESTRO HN

SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Gemcitabine in Treating Patients With Advanced Salivary Gland Cancer That Cannot Be Removed During Surgery

Oxaliplatin and Capecitabine in Treating Patients With Relapsed or Metastatic Head and Neck Cancer

Docetaxel in Treating Patients With Solid Tumors

DOVE

Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer

Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Dasatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

EF5 Compared With Other Methods of Detecting Oxygen Levels in Tumor Cells of Patients With Head and Neck Cancer

Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

Vaccine Therapy Plus Biological Therapy in Treating Adults With Metastatic Solid Tumors

Flavopiridol in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Ixabepilone in Treating Patients With Metastatic or Recurrent Squamous Cell Cancer of the Head and Neck

Bortezomib Followed by the Addition of Doxorubicin at Disease Progression in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma (Cancer) of the Head and Neck

Gemcitabine in Treating Patients With Recurrent or Metastatic Adenoid Cystic Cancer of the Head and Neck

Irinotecan and Cisplatin in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Celecoxib in Treating Patients With Early-Stage Head and Neck Cancer or Non-Small Cell Lung Cancer

Cetuximab and Stereotactic Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer That Cannot Be Removed By Surgery