Clinical Trials

Bone Neoplasms, Chondrosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT06541262 2026-03-02

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

104 enrolled

CNSSarcoma

Liposarcoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT04851119 2026-02-24

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

CNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

147 enrolled

Carcinoma, Hepatocellular, Lymphoma, Non-Hodgkin, Melanoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Ewing, Osteosarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Hepatoblastoma, Desmoid Tumors

NCT05918640 2026-02-23

LiFFT

63 enrolled

Neoplasms, Sarcoma, Ewing, Desmoplastic Small Round Cell Tumor

NCT06709495 2026-02-19

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

63 enrolled

GastrointestinalGynecologicSarcoma

Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Desmoplastic Small Round Cell Tumor

NCT07197554 2026-02-18

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

Phase 1 Recruiting

171 enrolled

Biliary Tract Neoplasms, Carcinoma, Hepatocellular, Neoplasms, Sarcoma, Ewing, Endometrial Neoplasms

NCT04055220 2026-02-17

REGOSTA

168 enrolled

Pathologic Complete Response, Bone Neoplasms, Chondrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Patient Compliance, Sarcoma, Ewing, Osteosarcoma, Histiocytoma, Malignant Fibrous

NCT04901702 2026-02-09

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

CNSGastrointestinalGenitourinarySarcoma

90 enrolled

Neoplasms, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT06387485 2026-02-06

A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning

150 enrolled

Chondrosarcoma, Fibrosarcoma, Sarcoma, Ewing, Osteosarcoma, Histiocytoma, Benign Fibrous

NCT05734066 2026-02-03

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

60 enrolled

Sarcoma, Sarcoma, Ewing

NCT05779670 2026-02-03

ADER

Recruiting

50 enrolled

Bone Neoplasms, Chondrosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT07172958 2026-01-27

SABRE

Phase 1 Recruiting

18 enrolled

CNSGenitourinarySarcoma

Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing

NCT07188532 2026-01-23

BEAR

141 enrolled

Sarcoma, Ewing

NCT04995003 2026-01-22

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

Phase 1 Recruiting

25 enrolled

Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial

NCT06068075 2026-01-22

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD

340 enrolled

Sarcoma, Ewing, Neuroectodermal Tumors, Primitive, Peripheral

NCT05046314 2026-01-14

A Clinical Study of TK216 in Patients With Relapsed or Refractory Ewing's Sarcoma

Phase 2 Recruiting

30 enrolled

Recurrence, Sarcoma, Ewing

NCT04845893 2026-01-02

EWOss

Recruiting

100 enrolled