Clinical Trials Browser

Phase 1 × INDUSTRY × Sarcoma, Synovial × Clear all

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioblastoma, Glioma, Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT06946225 2026-01-08

ACTengine® IMA203 Combined With mRNA-4203

Phase 1 Recruiting

15 enrolled

DermatologicSarcoma

Melanoma, Sarcoma, Synovial

NCT05492682 2025-09-05

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

Phase 1 Active not recruiting

15 enrolled

BreastDermatologicGastrointestinalSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma, Sarcoma, Osteosarcoma, Sarcoma, Synovial, Colorectal Neoplasms, Liposarcoma, Myxoid, Triple Negative Breast Neoplasms

NCT06644755 2025-07-24

First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors

Phase 1 Recruiting

150 enrolled

GenitourinarySarcoma

Urinary Bladder Neoplasms, Sarcoma, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT04965753 2025-03-04

FHD-609 in Subjects With Advanced Synovial Sarcoma or Advanced SMARCB1-Loss Tumors

Phase 1 Terminated

55 enrolled

Sarcoma

Sarcoma, Sarcoma, Synovial, Rhabdoid Tumor

NCT04537715 2025-02-19

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

Phase 1 Completed

42 enrolled 39 charts

LymphoidOther hematologic neoplasmOther solid neoplasmSarcomaThoracic

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mesothelioma, Sarcoma, Sarcoma, Synovial, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Hematologic Neoplasms

NCT06748872 2024-12-27

EPITOME-1015-I

Phase 1 Not yet recruiting

55 enrolled

GynecologicSarcoma

Carcinoma, Ovarian Epithelial, Sarcoma, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT05355753 2024-12-17

A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors

Phase 1 Terminated

49 enrolled

Sarcoma

Chondrosarcoma, Extraskeletal Myxoid, Chordoma, Sarcoma, Sarcoma, Synovial

NCT02601937 2024-10-03

EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma

Phase 1 Completed

109 enrolled 25 charts

Sarcoma

Sarcoma, Synovial, Rhabdoid Tumor

NCT03604783 2024-09-19

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

Phase 1 Terminated

74 enrolled

Sarcoma

Liposarcoma, Neoplasm Metastasis, Neoplasms, Sarcoma, Sarcoma, Ewing, Sarcoma, Synovial

NCT04176016 2024-02-02

Phase I Study of Radiolabeled OTSA101-DTPA in Patients With Relapsed or Refractory Synovial Sarcoma

Phase 1 Terminated

12 enrolled

Sarcoma

Recurrence, Sarcoma, Synovial

NCT03132922 2024-01-22

MAGE-A4ᶜ¹º³²T for Multi-Tumor

Phase 1 Active not recruiting

71 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Adenocarcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Sarcoma, Synovial, Liposarcoma, Myxoid

Clinical Trials

CLOVER-2

ACTengine® IMA203 Combined With mRNA-4203

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors

FHD-609 in Subjects With Advanced Synovial Sarcoma or Advanced SMARCB1-Loss Tumors

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

EPITOME-1015-I

A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors

EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

Phase I Study of Radiolabeled OTSA101-DTPA in Patients With Relapsed or Refractory Synovial Sarcoma

MAGE-A4ᶜ¹º³²T for Multi-Tumor