NCT07001995 2026-03-16Limertinib Plus Carboplatin and Etoposide for EGFR-mutant NSCLC With SCLC Transformation After EGFR-TKI ProgressionHunan Province Tumor HospitalPhase 2 Not yet recruiting30 enrolled
NCT07472517 2026-03-16DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard ChemotherapyBoehringer IngelheimPhase 3 Not yet recruiting670 enrolled
NCT06449209 2026-03-12Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With ChemotherapyBioNTech SEPhase 2 Active not recruiting110 enrolled
NCT05091567 2026-03-10IMforteHoffmann-La RochePhase 3 Active not recruiting660 enrolled 23 charts 1 FDA
NCT05068232 2026-03-04Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)University of ChicagoPhase 2 Recruiting49 enrolled
NCT06646276 2026-03-04A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).Bristol-Myers SquibbPhase 3 Recruiting530 enrolled
NCT06047379 2026-03-02Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain MetastasisNeonc Technologies, Inc.Phase 1/2 Recruiting134 enrolled
NCT05815160 2026-02-27Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based TherapyDebiopharm International SAPhase 1 Active not recruiting34 enrolled
NCT05403723 2026-02-19Adaptive SBRT Plus Chemoimmunotherapy for ES-SCLCUniversity of Maryland, BaltimorePhase 1 Suspended50 enrolled