Clinical Trials

Phase 1 Active not recruiting

Small Cell Lung Carcinoma

NCT05599984 2025-10-20

Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors

288 enrolled

CNSEndocrineThoracic

Neoplasms, Central Nervous System Neoplasms, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT04924101 2025-07-23

KEYNOTE-B99

Phase 2 Completed

126 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Small Cell Lung Carcinoma

NCT04774380 2025-05-23

LUMINANCE

152 enrolled 17 charts

Small Cell Lung Carcinoma

NCT04005716 2025-02-28

Study of Platinum Plus Etoposide With or Without Tislelizumab in Participants With Untreated Extensive-Stage Small Cell Lung Cancer

457 enrolled 20 charts

Small Cell Lung Carcinoma

NCT03509012 2025-01-14

CLOVER

Phase 3 Active not recruiting

105 enrolled

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT05566041 2024-10-31

REPLATINUM

292 enrolled

Small Cell Lung Carcinoma

NCT02815592 2024-09-04

Trial of BMS-986012 in Combination With Platinum and Etoposide

12 enrolled

Small Cell Lung Carcinoma

NCT03850067 2024-08-26

A Safety, Tolerability and Preliminary Efficacy Evaluation of CC-90011 Given in Combination With Cisplatin and Etoposide in Subjects With First Line, Extensive Stage Small Cell Lung Cancer

90 enrolled

Small Cell Lung Carcinoma

NCT00791154 2024-08-23

SCLC

Phase 1/2 Terminated

213 enrolled 16 charts

Lung Neoplasms, Pleural Effusion, Malignant, Small Cell Lung Carcinoma

NCT03699956 2024-03-26

REPLATINUM

Phase 3 Terminated

18 enrolled

Classical hematologySarcomaThoracic

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT02797977 2023-06-22

A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects

Phase 1/2 Completed

153 enrolled

Fanconi Anemia, Sarcoma, Small Cell Lung Carcinoma

NCT03066778 2022-10-03

KEYNOTE-604

453 enrolled 23 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Small Cell Lung Carcinoma

NCT03116971 2020-09-16

Phase Ib/II Study of M3814 With Etoposide and Cisplatin in Small Cell Lung Cancer (SCLC) Extensive Disease (ED)

Phase 1 Terminated

2 enrolled

Small Cell Lung Carcinoma

NCT01859741 2020-09-09

PINNACLE

Phase 1/2 Terminated

172 enrolled 17 charts

Small Cell Lung Carcinoma

NCT01450761 2020-07-08

Trial in Extensive-Disease Small Cell Lung Cancer (ED-SCLC) Subjects Comparing Ipilimumab Plus Etoposide and Platinum Therapy to Etoposide and Platinum Therapy Alone

1,351 enrolled 10 charts

Small Cell Lung Carcinoma

NCT02819999 2020-03-12

A Study of Rovalpituzumab Tesirine (SC16LD6.5) in the Frontline Treatment of Patients With Extensive Stage Small Cell Lung Cancer

Phase 1 Terminated

28 enrolled

Small Cell Lung Carcinoma

NCT00388960 2019-11-19

Study of Amrubicin With or Without Cisplatin Versus Etoposide-cisplatin for Extensive Stage Small Cell Lung Cancer

Phase 2 Completed

99 enrolled

Small Cell Lung Carcinoma

NCT02949895 2019-08-12

Study of BMS-986012 in Subjects With Small Cell Lung Caner

7 enrolled

GastrointestinalGynecologicThoracic

Small Cell Lung Carcinoma

NCT01040312 2019-05-23

An Observational Study of CPT-11 Plus Platinum Analogues Regimens and UGT1A1 Genotypes in Solid Tumors

Completed

321 enrolled

Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Ovarian Neoplasms, Recurrence, Stomach Neoplasms, Small Cell Lung Carcinoma

NCT00320359 2017-03-01

Topotecan Plus Cisplatin Versus Etoposide Plus Cisplatin In 1st Line Extensive Disease Small Cell Lung Cancer

700 enrolled

Small Cell Lung Carcinoma

NCT00359359 2014-11-04

A Study of a New Chemotherapy Agent in Combination With Cisplatin to Treat Small Cell Lung Cancer

Phase 1/2 Completed

26 enrolled

Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT01187615 2014-07-08

Determination of Safety, Efficacy, and Pharmacokinetics of "Regorafenib" Combined With Pemetrexed and Cisplatin in Patients With Nonsquamous Non-Small Cell Lung Cancer

Phase 1 Terminated

9 enrolled

Small Cell Lung Carcinoma

NCT00043927 2013-08-21

Extensive Small Cell Lung Cancer Treatment Using An Investigational Drug Plus Chemotherapy In Chemotherapy-Naive Adults

760 enrolled

Small Cell Lung Carcinoma

NCT00977561 2013-02-25

A Study Of Cisplatin (Or Carboplatin) And Etoposide With Or Without Figitumumab (CP-751,871) In Patients With Extensive-Stage Small Cell Lung Cancer

Phase 2 Terminated

9 enrolled 7 charts

GenitourinaryOther solid neoplasmThoracic

Small Cell Lung Carcinoma

NCT01604863 2012-11-01

A Study of HGS1036 in Combination With Chemotherapy in Subjects With Advanced Solid Malignancies

Phase 1 Suspended

54 enrolled

Lung Neoplasms, Mesothelioma, Neoplasms, Prostatic Neoplasms, Small Cell Lung Carcinoma

NCT00143455 2010-02-18

Study Of Irinotecan Hydrochloride (Campto(R)) And Cisplatin Versus Etoposide And Cisplatin In Small Cell Lung Cancer

485 enrolled 14 charts

Small Cell Lung Carcinoma

NCT00447421 2009-10-28

A Study to Treat Small Cell Lung Cancer With a Combination of Cisplatin, Pemetrexed, and Radiotherapy

Phase 1/2 Terminated

9 enrolled 6 charts

Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT00475657 2009-05-29

Pemetrexed and Cisplatin as Treatment in Small Cell Lung Cancer

Phase 2 Terminated

5 enrolled 7 charts