Clinical Trials

30 enrolled

Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT04919382 2026-03-12

Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

56 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04170946 2026-03-05

Talazoparib

Phase 1 Recruiting

24 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04516070 2026-03-05

Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis

Phase 1 Active not recruiting

55 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT03223155 2026-03-04

COSINR

78 enrolled

Small Cell Lung Carcinoma

NCT05068232 2026-03-04

Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)

49 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT07402343 2026-03-04

T-BRAIN

34 enrolled

CNSThoracic

Brain Neoplasms, Small Cell Lung Carcinoma

NCT06719700 2026-03-03

Concurrent Chemoradiotherapy Combined With Toripalimab and Surufatinib in the Treatment of Limited-Stage Small Cell Lung Cancer

47 enrolled

Small Cell Lung Carcinoma

NCT07219251 2026-03-03

EVLC

194 enrolled

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms, Small Cell Lung Carcinoma

NCT05403723 2026-02-19

Adaptive SBRT Plus Chemoimmunotherapy for ES-SCLC

Phase 1 Suspended

50 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT07149363 2026-02-17

Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer

65 enrolled

Phase 1/2 Active not recruiting

Small Cell Lung Carcinoma

NCT03830918 2026-02-12

Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy

59 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT05419076 2026-02-11

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

62 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT05703269 2026-02-10

HYPOGRYPHE

BreastCNSDermatologicGenitourinaryThoracic

244 enrolled

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Small Cell Lung Carcinoma

NCT07398560 2026-02-10

Adebrelimab Combined With Oral Etoposide for Elderly Patients and Patients With Poor Performance Status in Small Cell Lung Cancer: An Exploratory Clinical Study

47 enrolled

Phase NA Enrolling by invitation

Small Cell Lung Carcinoma

NCT07390565 2026-02-09

YSQTG Combined With Immuno-chemotherapy for Extensive-Stage Small Cell Lung Cancer

308 enrolled

Phase EARLY_PHASE1 Recruiting

Small Cell Lung Carcinoma

NCT05620342 2026-02-05

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

24 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT07388875 2026-02-05

SKB264-ANLO

30 enrolled

Phase 1/2 Active not recruiting

Small Cell Lung Carcinoma

NCT05616624 2026-02-04

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

31 enrolled

Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT07242547 2026-02-04

MERLIN

37 enrolled

Phase NA Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Respiratory Tract Neoplasms, Thoracic Neoplasms, Small Cell Lung Carcinoma

NCT07383454 2026-02-03

Lung Cancer Screening in Population Who Had Never Smoked

2,500 enrolled

Carcinoma, Non-Small-Cell Lung, Disease, Lung Neoplasms, Small Cell Lung Carcinoma

NCT07339059 2026-01-30

SG and Immunotherapy as Maintenance Therapy for Extensive-stage Small-cell Lung Cancer

35 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT07376499 2026-01-29

Prospective, Single-arm, Phase II Clinical Study of Irinotecan Hydrochloride Liposome Injection Combined With Platinum and Immune Checkpoint Inhibitors Combined With Anlotinib for the Maintenance of Extensive Small Cell Lung Cancer After First-line Induction

31 enrolled

Small Cell Lung Carcinoma

NCT05223647 2026-01-28

TRIPLEX

Phase 3 Terminated

239 enrolled

Neoplasms, Small Cell Lung Carcinoma

NCT07373964 2026-01-28

A Prospective, Single-Arm, Single-Center Phase II Study Evaluating the Efficacy and Safety of Chidamide Combined With PD-L1 Inhibitor, Carboplatin, and Etoposide as First-Line Treatment in Patients With Extensive-Stage Small-Cell Lung Cancer (ES-SCLC)

36 enrolled

Small Cell Lung Carcinoma

NCT07057791 2026-01-27

PrE0510

60 enrolled

Small Cell Lung Carcinoma

NCT07357532 2026-01-22

Exploration of Treatment Strategies After Concurrent Chemoradiotherapy for LS-SCLC Guided by MRD

44 enrolled

Small Cell Lung Carcinoma

NCT06481813 2026-01-21

BREATHE

730 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT03467360 2026-01-20

ICAR

Phase 1 Recruiting

27 enrolled

Small Cell Lung Carcinoma

NCT06957314 2026-01-20

A Study of Hospital-at-Home for People Receiving Tarlatamab

70 enrolled

Phase 1 Active not recruiting

Small Cell Lung Carcinoma

NCT03923270 2026-01-08

Radiotherapy and Durvalumab/Durvalumab Combo (Tremelimumab/Olaparid) for Small Cell Lung Cancer

25 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04199741 2026-01-07

PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56

Phase 1/2 Recruiting

53 enrolled

Small Cell Lung Carcinoma

NCT00213798 2025-12-22

Detection of Plasma DNA in Non Small Cell and Small Cell Lung Cancer Patients

Phase NA Completed

200 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT07155200 2025-12-22

Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)

Phase 1/2 Recruiting

42 enrolled

Small Cell Lung Carcinoma

NCT03728361 2025-12-18

Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer

Phase 1/2 Not yet recruiting

55 enrolled

EndocrineNETThoracic

Lung Neoplasms, Carcinoma, Neuroendocrine, Neuroendocrine Tumors, Small Cell Lung Carcinoma

NCT07153055 2025-12-18

LOTS

16 enrolled

Small Cell Lung Carcinoma

NCT05450965 2025-12-17

Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

37 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04701307 2025-12-15

Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas

48 enrolled

EndocrineThoracic

Lung Neoplasms, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT06758700 2025-12-05

Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung Cancer

15 enrolled

Lung Diseases, Lung Neoplasms, Thoracic Neoplasms, Small Cell Lung Carcinoma

NCT04010357 2025-12-02

Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC

14 enrolled

Phase 1 Not yet recruiting

Small Cell Lung Carcinoma

NCT07249879 2025-11-25

This Study is an Open-lable, Phase I Study to Evaluate the Safety, Feasibility, Cytokinetics, and Preliminary Efficacy of GC511B in DLL3+ Relapsed/Refractory Small Cell Lung Cancer.

55 enrolled

Small Cell Lung Carcinoma

NCT05588388 2025-11-17

BELIEVE

39 enrolled

Small Cell Lung Carcinoma

NCT03672773 2025-11-10

TRIO-US L-07

35 enrolled

Small Cell Lung Carcinoma

NCT04373369 2025-11-03

Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

Phase 2 Terminated

11 enrolled 10 charts

Small Cell Lung Carcinoma

NCT04397003 2025-10-22

Personalized Neoantigen Vaccine in Combination With Durvalumab (MEDI4736) in Extensive Stage Small Cell Lung Cancer

6 enrolled

Small Cell Lung Carcinoma

NCT06807632 2025-10-20

A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer

Phase 1 Recruiting

24 enrolled

EndocrineGynecologicLymphoidOther solid neoplasmThoracic

Small Cell Lung Carcinoma

NCT05337735 2025-10-09

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

Phase 2 Suspended

140 enrolled

Mesothelioma, Malignant, Uterine Cervical Neoplasms, Hodgkin Disease, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT07206563 2025-10-03

Penfluridol for Relapsed/Refractory Small Cell Cancers

Phase 1/2 Not yet recruiting

33 enrolled

Recurrence, Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT04472949 2025-10-01

Thoracic Radiotherapy Plus Maintenance Durvalumab After First Line Carboplatin and Etoposide Plus Durvalumab in Extensive-stage Disease Small Cell Lung Cancer (ED-SCLC).

46 enrolled

Phase NA Active not recruiting

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04986670 2025-09-30

NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer

299 enrolled