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Phase 1 × Solid Tumor × Temozolomide × Clear all

Phase

Phase 2 1 Phase 1 1

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Other solid neoplasm 1

Conditions

Glioblastoma 94 Gliosarcoma 42 Glioma 37 Brain Neoplasms 34 Astrocytoma 31 Central Nervous System Neoplasms 26 Oligodendroglioma 21 Neuroblastoma 12 Melanoma 12 Medulloblastoma 12 Ependymoma 10 Neoplasms 8 Unspecified Adult Solid Tumor, Protocol Specific 6 Neoplasm Metastasis 6 Neuroectodermal Tumors, Primitive 5 Familial ependymoma 5 Choroid Plexus Neoplasms 5 Sarcoma, Ewing 4 Sarcoma 4 Recurrence 4 Osteosarcoma 4 Rhabdomyosarcoma 3 Precursor Cell Lymphoblastic Leukemia-Lymphoma 3 Pinealoma 3 Ovarian Neoplasms 3 Optic Nerve Glioma 3 Meningioma 3 Lymphoma 3 Glioma, Subependymal 3 Breast Neoplasms 3

Interventions

Docetaxel 8 pembrolizumab 7 Capecitabine 7 senaparib 6 Paclitaxel 6 Injections 6 Cisplatin 6 Irinotecan 5 Fluorouracil 5 Leucovorin 4 Cyclophosphamide 4 Bevacizumab 4 tislelizumab 3 pertuzumab 3 fludarabine 3 atezolizumab 3 Rifampin 3 Oxaliplatin 3 Itraconazole 3 Gemcitabine 3 fluzoparib 2 durvalumab 2 Trastuzumab 2 Nivolumab 2 Midazolam 2 Hydroxychloroquine 2 Carboplatin 2 130-nm albumin-bound paclitaxel 2 zimberelimab 1 vofatamab 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT00786669 2021-02-10

VITAC

Children's Hospital Medical Center, Cincinnati

Phase 1 Completed

Other solid neoplasm

Solid Tumor

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