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Phase 1 × Solid Tumors × adavosertib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Other solid neoplasm 1

Conditions

Advanced Solid Tumours 4 Squamous Cell Carcinoma of Head and Neck 2 Small Cell Lung Carcinoma 2 Ovarian Neoplasms 2 Leukemia, Myeloid, Acute 2 Glioblastoma 2 Vaginal Neoplasms 1 Uterine Cervical Neoplasms 1 Triple Negative Breast Neoplasms 1 Stomach Neoplasms 1 Solid Tumors 1 Neoplasm Metastasis 1 Myelodysplastic Syndromes 1 Muscle Invasive Bladder Cancer 1 Meningeal Carcinomatosis 1 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1 Laryngeal Neoplasms 1 Head and Neck Neoplasms 1 Gliosarcoma 1 Esophageal Squamous Cell Carcinoma 1 Esophageal Neoplasms 1 Diffuse Intrinsic Pontine Glioma 1 Colorectal Neoplasms 1 Carcinoma, Endometrioid 1 Brain Neoplasms 1 Blast Crisis 1 Astrocytoma 1 Advanced Solid Tumors 1 Adenocarcinoma Of Esophagus 1

Interventions

Paclitaxel 11 Gemcitabine 9 Carboplatin 8 atezolizumab 6 Bevacizumab 6 navitoclax 4 liposomal doxorubicin 4 Irinotecan 4 Erlotinib Hydrochloride 4 Cetuximab 4 Sunitinib 3 Oxaliplatin 3 Leucovorin 3 Injections 3 Fluorouracil 3 Docetaxel 3 Cyclophosphamide 3 tocilizumab 2 tislelizumab 2 temsirolimus 2 ridaforolimus 2 plocabulin 2 pembrolizumab 2 pazopanib 2 olaparib 2 linifanib 2 fludarabine 2 envafolimab 2 darinaparsin 2 brigimadlin 2

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT00648648 2023-09-21

MK-1775-001

Merck Sharp & Dohme LLC

Phase 1 Completed

206 enrolled 40 charts

Other solid neoplasm

Solid Tumors

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