Clinical Trials Browser

Phase 1 × Solid Tumors × Clear all

NCT05155332 2026-03-17

A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT06892379 2026-03-13

A Study of HS-20110 in Participants With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT04261413 2026-03-11

Phase Ia/Ib Study of RS-0139 in Patients With a Recurrent, Locally Advanced or Metastatic Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT03313778 2026-03-04

KEYNOTE-603

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors

NCT03448042 2026-02-27

A Study of Runimotamab in Participants With Locally Advanced or Metastatic HER2-Expressing Cancers

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors

NCT07176975 2026-02-27

A Study to Test How Well Different Doses of BI 1831169 in Combination With an Anti-PD1 Antibody Are Tolerated in Japanese People With Different Advanced Cancers

Phase 1 Not yet recruiting

Other solid neoplasm

Solid Tumors

NCT07030959 2026-02-25

Study of AUBE00 in Patients With Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT04250155 2026-02-24

An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors

NCT07181681 2026-02-23

A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT07123103 2026-02-17

A Study of XB371 Administered in Participants With Locally Advanced or Metastatic Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT07407985 2026-02-12

GK01IIT-TZ03

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors

NCT07395258 2026-02-09

A Study to Test Different Doses of BI 3923948 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

Phase 1 Not yet recruiting

Other solid neoplasm

Solid Tumors

NCT05372367 2026-02-03

A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT07351903 2026-01-20

GUARDIAN-02

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT00777582 2026-01-13

Phase I Comparative Bioavailability Study

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors

NCT07312903 2026-01-12

DPTX3186 in Wnt Pathway Activated Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT06227377 2025-12-24

QTX3034 in Patients With KRAS G12D Mutation

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT05836324 2025-12-18

A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT06727812 2025-12-18

Multicenter Phase I Study of HRS-6208 in Patients With Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT05471856 2025-12-17

A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT07159126 2025-12-10

A Study of DS3610a in Participants With Advanced Solid Tumor

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT07274085 2025-12-10

A Phase 1 Study of HDM2017 in Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT07231081 2025-11-17

Phase I Study of TX103 CAR-T Cells in Participants With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT05327946 2025-10-28

A Study in People With Advanced Cancer to Test How Well Different Doses of BI 770371 Alone or in Combination With Ezabenlimab Are Tolerated

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors

NCT02597036 2025-10-23

A Study of LY3127804 With Ramucirumab in Participants With Advanced Solid Tumors

Phase 1 Terminated

62 enrolled 25 charts

Other solid neoplasm

Solid Tumors

NCT06066424 2025-10-14

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT05976334 2025-10-06

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

Phase 1 Terminated

3 enrolled 19 charts

Other solid neoplasm

Solid Tumors

NCT06933524 2025-10-01

ATB-320-001A

Phase 1 Not yet recruiting

Other solid neoplasm

Solid Tumors

NCT06082960 2025-09-10

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors

NCT03762447 2025-08-11

A Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT02498912 2025-07-31

Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors

NCT06826313 2025-07-18

A Study of Intravenous VRT106 for Locally Advanced or Metastatic Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT05387265 2025-07-14

A Trial to Find Safe and Active Doses for an Investigational Drug, CX-904, for Patients With Advanced Solid Tumors

Phase 1 Terminated

Other solid neoplasm

Solid Tumors

NCT06410131 2025-07-01

Study in Patients With Advanced Solid Tumors to Evaluate the Safety of FTL008.16

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT04613492 2025-06-24

A Study of MEDI9253 in Combination With Durvalumab in Select Solid Tumors

Phase 1 Terminated

Other solid neoplasm

Solid Tumors

NCT06963281 2025-06-06

Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT04405778 2025-05-29

A Study of TAK-102 in Adult With Previously-Treated Solid Tumors

Phase 1 Terminated

Other solid neoplasm

Solid Tumors

NCT05164666 2025-05-29

A Study of TAK-103 in Adult With Solid Tumors

Phase 1 Terminated

Other solid neoplasm

Solid Tumors

NCT04642365 2025-05-21

A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors.

Phase 1 Terminated

49 enrolled 31 charts

Other solid neoplasm

Solid Tumors

NCT06710379 2025-04-09

A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT06816992 2025-03-20

ORIC-114 in Combination with Subcutaneous Amivantamab in Patients with EGFR Exon20 Insertion Mutant NSCLC

Phase 1 Recruiting

Other solid neoplasmThoracic

Solid Tumors

NCT06873542 2025-03-12

A Study of DC05F01 in Chinese Patients with Advanced or Metastatic Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT01251562 2025-02-19

Safety Study of Sterile Compound C31510 for Injection to Subjects With Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT02667873 2025-02-10

A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT05613036 2025-01-22

A Study in People With Advanced Cancer to Test How BI 907828 is Processed in the Body

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT02610361 2024-12-27

Study of the Safety and Pharmacokinetics of BGB-283 in Patients With Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT00909025 2024-11-21

Safety and Tolerability Study of Claudiximab in Patients With Advanced Gastroesophageal Cancer

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT02699515 2024-11-18

MSB0011359C (M7824) in Participants With Metastatic or Locally Advanced Solid Tumors

Phase 1 Completed

114 enrolled 29 charts

Other solid neoplasm

Solid Tumors

NCT05650242 2024-11-08

A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BA1106 in Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT02038673 2024-10-31

An Open-label Phase I Study of Orally Available Novel Small-molecule Fibroblast Growth Factor Receptors (FGFR) 1,2,3 and 4 Inhibitor, ASP5878 at Single and Multiple Doses in Patients With Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumors