Clinical Trials

242 enrolled

Aneurysm, Brain Diseases, Brain Neoplasms, Hydrocephalus, Spinal Cord Neoplasms, Spinal Curvatures, Spinal Diseases, Spinal Stenosis, Trigeminal Neuralgia, Spinal Fractures

NCT06161974 2025-02-21

Study of Olutasidenib and Temozolomide in HGG

Phase 2 Recruiting

60 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Spinal Cord Neoplasms

NCT03839914 2024-12-04

Evaluating the Efficacy and Safety of Intra-wound Vancomycin Powder in High Risk Patients

Phase NA Recruiting

76 enrolled

Spinal Cord Neoplasms, Surgical Wound Infection, Wounds and Injuries

NCT04525014 2024-10-31

PIRATE

Phase 1 Terminated

2 enrolled

Brain Neoplasms, Neoplasms, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT06613295 2024-09-25

SABR-MESCC

Phase NA Recruiting

128 enrolled

Spinal Cord Neoplasms, Spinal Neoplasms

NCT04219969 2024-05-09

FDG PET-MRI for the Diagnosis of Spinal Cord Lesions

11 enrolled

Spinal Cord Neoplasms

NCT01236560 2024-02-20

Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma

Phase 2/3 Completed

101 enrolled 15 charts

Astrocytoma, Spinal Cord Neoplasms

NCT01624220 2023-12-05

A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

41 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasms, Unknown Primary, Prostatic Neoplasms, Sarcoma, Spinal Cord Neoplasms, Thyroid Neoplasms

NCT05096468 2023-07-06

Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.

Phase 2/3 Completed

90 enrolled

Pain, Postoperative, Spinal Cord Neoplasms

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

Phase 2 Completed

118 enrolled 8 charts

CNSSarcoma

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT05678608 2023-01-10

Surgical Outcome of Dorsolumbar Intradural Extramedullary Spinal Cord Tumors

Phase NA Unknown

20 enrolled

Spinal Cord Neoplasms

NCT04578691 2022-11-10

Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery

55 enrolled

Spinal Cord Neoplasms, Spinal Injuries

NCT02085941 2022-08-15

Image-guided Cryoablation of Head, Neck and Spine Tumors

30 enrolled 10 charts

CNSHead & Neck

Head and Neck Neoplasms, Spinal Cord Neoplasms

NCT05493228 2022-08-09

Dexmedetomidine Infusion on Intraoperative Propofol,Fentanyl Requirements in Spine Surgery for Pediatric Cancer Patients

Phase 3 Unknown

38 enrolled

Spinal Cord Neoplasms

NCT02013297 2022-03-08

SBRT

61 enrolled

CNSThoracic

Brain Neoplasms, Ependymoma, Lung Neoplasms, Spinal Cord Neoplasms

NCT05106179 2021-11-03

The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma

Phase 4 Unknown

1,000 enrolled

Spinal Cord Neoplasms

NCT02225223 2021-08-11

STARRT

35 enrolled 12 charts

Pain, Spinal Cord Neoplasms

NCT04968730 2021-07-20

Establishment and Application of Early Postoperative Activity Plan for Patients After Hemi-laminectomy for Lumbar Spinal Tumor Resection

Phase NA Unknown

100 enrolled

Spinal Cord Neoplasms

NCT01637766 2020-08-03

SIAC

12 enrolled

Spinal Cord Compression, Spinal Cord Neoplasms, Spinal Diseases

NCT03893110 2020-04-30

Carbon PEEK Versus Titanium Pedicle Screws in the Treatment of Spinal Tumors

Phase NA Withdrawn

Spinal Cord Neoplasms

NCT04331431 2020-04-02

Outcomes of the Intradural Extramedullary Tumors Resection

24 enrolled

Spinal Cord Neoplasms

NCT01921595 2019-03-29

Impact of Balanced Slat Colloid HES 130/0.42 on Coagulation Profiles in Patients Undergoing Spinal Cord Tumor Surgery

6 enrolled

Spinal Cord Neoplasms, Thrombosis

NCT00826241 2019-03-22

Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma

Phase 2 Completed

58 enrolled 11 charts

Brain Neoplasms, Ependymoma, Spinal Cord Neoplasms

NCT03050203 2019-01-28

kit

37 enrolled 5 charts

Bone Diseases, Spinal Cord Neoplasms, Osteoarthritis, Spine

NCT02613390 2019-01-10

Safety Evaluation of Intra-Operative MRI-Based Guidance for Laser Ablation of Epidural Metastasis

11 enrolled

Phase EARLY_PHASE1 Completed

Spinal Cord Neoplasms

NCT00452868 2018-09-07

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

14 enrolled 7 charts

Familial ependymoma, Astrocytoma, Medulloblastoma, Radiation Injuries, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neurotoxicity Syndromes, Optic Nerve Glioma

NCT03585699 2018-07-19

Percutaneous Fluoroscopic vs CT Guided Core Needle Biopsy for Spinal Infection and Tumor

60 enrolled

Spinal Cord Neoplasms, Discitis

NCT00077207 2018-05-16

Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma

66 enrolled 13 charts

Brain Neoplasms, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT00276640 2018-04-20

SIOP-LGG-2004

3,417 enrolled

Astrocytoma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00381797 2017-11-28

Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma

Phase 2 Completed

97 enrolled 35 charts

Familial ependymoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms

NCT01567787 2017-02-10

NF01

Phase NA Withdrawn

CNSSarcoma

Neurofibroma, Spinal Cord Neoplasms, Nerve Sheath Neoplasms, Neurofibrosarcoma

NCT00326664 2016-03-07

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

55 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT02252185 2015-12-03

A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery

106 enrolled

Spinal Cord Neoplasms, Spinal Stenosis, Spondylolisthesis, Spinal Fractures, Intervertebral Disc Degeneration

NCT02603874 2015-11-13

The Development of a Vertebra Localizing Aid Medical Device

Phase NA Unknown

100 enrolled

Spinal Cord Neoplasms, Spinal Fractures

NCT01308489 2015-06-08

Minimally Invasive Surgery in Treating Patients With Spinal Tumors

7 enrolled

Spinal Cord Neoplasms

NCT01158300 2015-05-04

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

28 enrolled

CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Medulloblastoma, Meningioma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

Phase 1 Terminated

129 enrolled

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT00458744 2014-08-08

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Phase 1 Withdrawn

CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Recurrence, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

NCT00107458 2014-08-07

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

26 enrolled